anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) Antikörper

alphaKGDHC encodes one subunit of the 2-oxoglutarate dehydrogenase complex. Zusätzlich bieten wir Ihnen alpha Ketoglutarate Dehydrogenase Kits (31) und alpha Ketoglutarate Dehydrogenase Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
alphaKGDHC 4967 Q02218
alphaKGDHC 18293 Q60597
alphaKGDHC 360975 Q5XI78
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Top anti-alpha Ketoglutarate Dehydrogenase Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: OGDH Sample Tissue: Human DLD1 Antibody Dilution: 1.0ug/ml WB Suggested Anti-OGDH Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB OGDH Antibody (C-term) (ABIN657365) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the OGDH antibody detected the OGDH protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image OGDH antibody [C2C3], C-term detects OGDH protein at Mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in -20℃ 100% MeOH for 5 min. Green: OGDH protein stained by OGDH antibody [C2C3], C-term , diluted at 1:500. Blue: Hoechst 33343 staining. IHC-P Image OGDH antibody [C2C3], C-term detects OGDH protein at mitochondria on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. OGDH antibody [C2C3], C-term , dilution: 1:500. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: OGDH Antibody [NBP2-19622] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 7. 5% SDS PAGE gel, diluted at 1:5000. Western Blot: OGDH Antibody [NBP2-19622] - Sample (30ug whole cell lysate) A: 293T B: A431 C: H1299 D: HeLa S3 E: Hep G2 F: MOLT4 G: Raji 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of OGDH staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Western blot analysis of OGDH expression in mouse heart (A), mouse brain (B), rat kidney (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various tissues, using OGDH antibody. Immunofluorescence analysis of U2OS cell using OGDH antibody. Blue: DAPI for nuclear staining. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert WB OGDH antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details

alphaKGDHC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen alpha Ketoglutarate Dehydrogenase Interaktionspartner

Human alpha Ketoglutarate Dehydrogenase (alphaKGDHC) Interaktionspartner

  1. oxoglutarate dehydrogenase (OGDH) and lipoic acid synthase (LIAS (zeige LIAS Antikörper)), which when mutated stabilize HIF1alpha (zeige HIF1A Antikörper) in a non-hydroxylated form.

  2. Tissue-specific expression of OGDH splice variants may thus provide a mechanism that tunes the control of the enzyme to the specialized metabolic and signalling needs of individual cell types

  3. Acute inhibition of alpha-ketoglutarate dehydrogenase produces effects on calcium opposite to those in Alzheimer's disease (AD), while the chronic or long-term inhibition of alpha-KGDHC mimicked the AD-related changes in calcium.

  4. 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability is regulated by the RING finger ubiquitin ligase Siah

  5. Reduction in the E2k (zeige DLST Antikörper) subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.

Mouse (Murine) alpha Ketoglutarate Dehydrogenase (alphaKGDHC) Interaktionspartner

  1. Taken together, our results indicate that the redox sensing and ROS (zeige ROS1 Antikörper) forming properties of Pdh (zeige PDP Antikörper) and Ogdh are linked to S-glutathionylation

  2. pre-incubation of permeabilized liver mitochondria from mouse depleted of GSH showed an approximately ~3.5-fold increase in Ogdh-mediated O2(-)/H2O2 production that was matched by a significant decrease in NADH formation which could be reversed by Grx2 (zeige GRX2 Antikörper). Taken together, our results demonstrate GSH and GSSG modulate ROS (zeige ROS1 Antikörper) production by Ogdh through S-glutathionylation of different subunits

  3. The nitration degree of alpha-OGDH for diabetic mouse is higher than that for control mouse, indicating that alpha-OGDH of the diabetic mouse suffered from more intense oxidative damage.

  4. Alpha-ketoglutarate dehydrogenase is a primary site of ROS (zeige ROS1 Antikörper) production in normally functioning mitochondria.

  5. In the postnatal mouse brain,high mRNA levels of d1401/Ogdh were observed in the olfactory bulb, hippocampus, cerebellum, and pons.

alpha Ketoglutarate Dehydrogenase (alphaKGDHC) Antigen-Profil

Protein Überblick

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit alphaKGDHC

  • oxoglutarate dehydrogenase (OGDH) Antikörper
  • oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (Ogdh) Antikörper
  • oxoglutarate dehydrogenase (Ogdh) Antikörper
  • 2210403E04Rik Antikörper
  • 2210412K19Rik Antikörper
  • AA409584 Antikörper
  • AKGDH Antikörper
  • d1401 Antikörper
  • E1k Antikörper
  • mKIAA4192 Antikörper
  • OGDC Antikörper

Bezeichner auf Proteinebene für alphaKGDHC

2-oxoglutarate dehydrogenase, mitochondrial , 2-oxoglutarate dehydrogenase complex component E1 , OGDC-E1 , oxoglutarate decarboxylase , oxoglutarate dehydrogenase (succinyl-transferring) , 2-oxoglutarate dehydrogenase E1 component, mitochondrial , alpha-ketoglutarate dehydrogenase , oxoglutarate dehydrogenase (lipoamide)

GENE ID SPEZIES
426429 Gallus gallus
4967 Homo sapiens
475499 Canis lupus familiaris
534599 Bos taurus
18293 Mus musculus
360975 Rattus norvegicus
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