alpha Hemoglobin Stabilizing Protein (aHSP) ELISA Kits

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Zusätzlich bieten wir Ihnen aHSP Antikörper (46) und aHSP Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
aHSP 51327 Q9NZD4
aHSP 170812 Q9CY02
Anti-Ratte aHSP aHSP 293522  
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Top aHSP ELISA Kits auf antikoerper-online.de

Showing 10 out of 19 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.055 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
$832.83
Details
Human 13.3 pg/mL 31.2 pg/mL - 2000 pg/mL   96 Tests Anmelden zum Anzeigen 8 bis 12 Tage
$693.25
Details
Maus 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Huhn 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Meerschweinchen 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Schwein 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Kaninchen 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Affe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Maus 0.188 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$475.20
Details
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details

Weitere ELISA Kits für aHSP Interaktionspartner

Human alpha Hemoglobin Stabilizing Protein (aHSP) Interaktionspartner

  1. Findings indicate that alpha-hemoglobin-stabilizing protein (AHSP) expression is a biomarker of hemoglobin (zeige HBB ELISA Kits) H (HbH (zeige HBA1 ELISA Kits)) disease severity and infer an important role of AHSP in modulating the pathophysiology of this disease.

  2. AHSP is predominantly expressed in erythroid precursors in bone marrow biopsy specimens from patients with hematologic malignancies.

  3. AHSP expression was higher in patients with sickle cell anemia versus thalassemia, with no significant difference between BTM and BTI. Expression was higher in patients with NTDT and on hydroxyurea therapy.

  4. In maturing RBC (zeige CACNA1C ELISA Kits) progenitors AHSP bind to free alpha-globin (zeige HBA1 ELISA Kits) chains to increase the HbA (zeige SCN2A ELISA Kits) production. (Review)

  5. analysis showed binding of STAT3 (zeige STAT3 ELISA Kits) to AHSP promoter and binding was significantly augmented with IL6 (zeige IL6 ELISA Kits) stimulation and upon alpha-globin (zeige HBA1 ELISA Kits) overexpression

  6. The relationship between AHSP gene expression, disease severity, and the beta/alpha globin (zeige HBA1 ELISA Kits) mRNA ratio was studied among different homozygote beta-thalassemia patients.

  7. alpha-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy (zeige GCG ELISA Kits)-alpha-hemoglobin and weakens the iron-oxygen bond.

  8. alpha-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of alpha-subunits of human HbA (zeige SCN2A ELISA Kits) with hydrogen peroxide.

  9. AHSP acts as a molecular chaperone (zeige HSP90AA1 ELISA Kits) by rapidly binding and stabilizing met-alpha hemichrome folding intermediates

  10. AHSP could be a secondary compensatory mechanism in red blood cells to counterbalance the excess of alpha-globin (zeige HBA1 ELISA Kits) chains in HbE (zeige HBe1 ELISA Kits)/beta-thalassaemia individuals.

Mouse (Murine) alpha Hemoglobin Stabilizing Protein (aHSP) Interaktionspartner

  1. role of alpha-hemoglobin stabilizing protein in hemoglobin assembly

  2. Endogenous AHSP is not limiting for alpha-globin (zeige HBA-A1 ELISA Kits) detoxification in beta-thalassemic mice.

  3. activin A (zeige INHBA ELISA Kits) does not appear to affect the exocrine or endocrine components of the pancreas, but promotes differentiation of pancreatic tissue into intestine via a Shh (zeige SHH ELISA Kits)-dependent mechanism

  4. Loss of AHSP impairs erythropoiesis and exacerbates beta-thalassemia.

  5. These results support the hypothesis that EKLF (zeige KLF1 ELISA Kits) acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin (zeige HBB ELISA Kits) genes and indicate that EKLF (zeige KLF1 ELISA Kits) may play similar roles for other erythroid genes.

  6. developmental stage- and differentiation state-specific regulation of the nuclear transport of EKLF (zeige KLF1 ELISA Kits) might be one of the steps necessary for the switch-on of the mammalian adult beta globin (zeige HBB ELISA Kits) gene transcription

  7. AHSP also acts as a molecular chaperone to stabilize nascent alpha-globin for hemoglobin A assembly

  8. The expression of AHSP in a subclone of murine erythroleukemia cells in relationship to prion protein (zeige PRNP ELISA Kits) on the cell surface is reported.

aHSP Antigen-Profil

Beschreibung des Gens

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity).

Genbezeichner und Symbole assoziert mit aHSP

  • alpha hemoglobin stabilizing protein (AHSP) Antikörper
  • alpha hemoglobin stabilizing protein (Ahsp) Antikörper
  • alpha-hemoglobin-stabilizing protein-like (LOC100620111) Antikörper
  • AHSP Antikörper
  • EDRF Antikörper
  • Eraf Antikörper

Bezeichner auf Proteinebene für aHSP

alpha hemoglobin stabilizing protein , erythroid associated factor , alpha hemoglobin stabilising protein , alpha-hemoglobin-stabilizing protein , erythroid differentiation associated factor , erythroid differentiation-related factor , erythroid-associated factor

GENE ID SPEZIES
454073 Pan troglodytes
714392 Macaca mulatta
100127218 Ovis aries
100340962 Oryctolagus cuniculus
51327 Homo sapiens
170812 Mus musculus
338381 Bos taurus
293522 Rattus norvegicus
100712877 Cavia porcellus
100620111 Sus scrofa
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