anti-alpha Hemoglobin Stabilizing Protein (aHSP) Antikörper

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Zusätzlich bieten wir Ihnen aHSP Kits (19) und aHSP Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
aHSP 51327 Q9NZD4
aHSP 170812 Q9CY02
aHSP 293522  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-aHSP Antikörper auf antikoerper-online.de

Showing 10 out of 46 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert FM, IHC (fp), ELISA, WB Immunohistochemistry of Rabbit anti-AHSP antibody. Tissue: A. Normal bone marrow, H&E. B. CD235a stains both nucleated EPs and mature, anucleate RBCs. C. AHSP stains nucleated EPs, but not mature, anucleate RBCs. D. CD71 stains nucleated EPs, but not mature, anucleate RBCs. Fixation: acetic acid-zinc-formalin and formalin fixation, embedded in paraffin Antigen retrieval: TRIS-EDTA pH9.0 Primary antibody: AHSP antibody at 1:8,000 for overnight at 4°C Secondary antibody: anti-rabbit secondary at (1:10,000 for 45 min at RT) Localization: Anti-AHSP is cytoplasmic Staining: AHSP antibody as precipitated brown signal with a purple nuclear counterstain using Bond-max™ – fully automated for IHC. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$379.00
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged ERAF is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.96 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of AHSP expression in mouse liver (A), rat liver (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$324.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$316.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$342.00
Details
Human Kaninchen Unkonjugiert IC, IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$600.29
Details
Human Kaninchen Unkonjugiert IHC, WB   50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various tissues, using AHSP antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details

aHSP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
,
,
, , , , , , , , , , , , ,
Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-aHSP Antikörper

  1. Mouse (Murine) Polyclonal aHSP Primary Antibody für FM, IHC (fp) - ABIN1043695 : Nasimuzzaman, Khandros, Wang, Kong, Zhao, Weiss, Rivella, Weiss, Persons: Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia. in American journal of hematology 2010 (PubMed)

  2. Human Monoclonal aHSP Primary Antibody für ELISA, WB - ABIN526641 : Wang, Fang, Guo, Ren, Zhang: Transgenic human alpha-hemoglobin stabilizing protein could partially relieve betaIVS-2-654-thalassemia syndrome in model mice. in Human gene therapy 2010 (PubMed)

Weitere Antikörper gegen aHSP Interaktionspartner

Human alpha Hemoglobin Stabilizing Protein (aHSP) Interaktionspartner

  1. Findings indicate that alpha-hemoglobin-stabilizing protein (AHSP) expression is a biomarker of hemoglobin (zeige HBB Antikörper) H (HbH (zeige HBA1 Antikörper)) disease severity and infer an important role of AHSP in modulating the pathophysiology of this disease.

  2. AHSP is predominantly expressed in erythroid precursors in bone marrow biopsy specimens from patients with hematologic malignancies.

  3. AHSP expression was higher in patients with sickle cell anemia versus thalassemia, with no significant difference between BTM and BTI. Expression was higher in patients with NTDT and on hydroxyurea therapy.

  4. In maturing RBC (zeige CACNA1C Antikörper) progenitors AHSP bind to free alpha-globin (zeige HBA1 Antikörper) chains to increase the HbA (zeige SCN2A Antikörper) production. (Review)

  5. analysis showed binding of STAT3 (zeige STAT3 Antikörper) to AHSP promoter and binding was significantly augmented with IL6 (zeige IL6 Antikörper) stimulation and upon alpha-globin (zeige HBA1 Antikörper) overexpression

  6. The relationship between AHSP gene expression, disease severity, and the beta/alpha globin (zeige HBA1 Antikörper) mRNA ratio was studied among different homozygote beta-thalassemia patients.

  7. alpha-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy (zeige GCG Antikörper)-alpha-hemoglobin and weakens the iron-oxygen bond.

  8. alpha-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of alpha-subunits of human HbA (zeige SCN2A Antikörper) with hydrogen peroxide.

  9. AHSP acts as a molecular chaperone (zeige HSP90AA1 Antikörper) by rapidly binding and stabilizing met-alpha hemichrome folding intermediates

  10. AHSP could be a secondary compensatory mechanism in red blood cells to counterbalance the excess of alpha-globin (zeige HBA1 Antikörper) chains in HbE (zeige HBe1 Antikörper)/beta-thalassaemia individuals.

Mouse (Murine) alpha Hemoglobin Stabilizing Protein (aHSP) Interaktionspartner

  1. role of alpha-hemoglobin stabilizing protein in hemoglobin assembly

  2. Endogenous AHSP is not limiting for alpha-globin (zeige HBA-A1 Antikörper) detoxification in beta-thalassemic mice.

  3. activin A (zeige INHBA Antikörper) does not appear to affect the exocrine or endocrine components of the pancreas, but promotes differentiation of pancreatic tissue into intestine via a Shh (zeige SHH Antikörper)-dependent mechanism

  4. Loss of AHSP impairs erythropoiesis and exacerbates beta-thalassemia.

  5. These results support the hypothesis that EKLF (zeige KLF1 Antikörper) acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin (zeige HBB Antikörper) genes and indicate that EKLF (zeige KLF1 Antikörper) may play similar roles for other erythroid genes.

  6. developmental stage- and differentiation state-specific regulation of the nuclear transport of EKLF (zeige KLF1 Antikörper) might be one of the steps necessary for the switch-on of the mammalian adult beta globin (zeige HBB Antikörper) gene transcription

  7. AHSP also acts as a molecular chaperone to stabilize nascent alpha-globin for hemoglobin A assembly

  8. The expression of AHSP in a subclone of murine erythroleukemia cells in relationship to prion protein (zeige PRNP Antikörper) on the cell surface is reported.

aHSP Antigen-Profil

Protein Überblick

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity).

Genbezeichner und Symbole assoziert mit aHSP

  • alpha hemoglobin stabilizing protein (AHSP) Antikörper
  • alpha hemoglobin stabilizing protein (Ahsp) Antikörper
  • alpha-hemoglobin-stabilizing protein-like (LOC100620111) Antikörper
  • AHSP Antikörper
  • EDRF Antikörper
  • Eraf Antikörper

Bezeichner auf Proteinebene für aHSP

alpha hemoglobin stabilizing protein , erythroid associated factor , alpha hemoglobin stabilising protein , alpha-hemoglobin-stabilizing protein , erythroid differentiation associated factor , erythroid differentiation-related factor , erythroid-associated factor

GENE ID SPEZIES
454073 Pan troglodytes
714392 Macaca mulatta
100127218 Ovis aries
100340962 Oryctolagus cuniculus
51327 Homo sapiens
170812 Mus musculus
338381 Bos taurus
293522 Rattus norvegicus
100712877 Cavia porcellus
100620111 Sus scrofa
Ausgewählte Anbieter für anti-aHSP (aHSP) Antikörper
Haben Sie etwas anderes gesucht?