anti-Zinc Metalloproteinase, Ste24 (Zmpste24) Antikörper

Zmpste24 encodes a member of the peptidase M48A family. Zusätzlich bieten wir Ihnen Zinc Metalloproteinase, Ste24 Proteine (7) und Zinc Metalloproteinase, Ste24 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Zmpste24 10269 O75844
Zmpste24 313564  
Zmpste24 230709 Q80W54
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Top anti-Zinc Metalloproteinase, Ste24 Antikörper auf antikoerper-online.de

Showing 10 out of 126 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ZMPSTE24 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Detection of ZMPSTE24 in human testis using ABIN250782. Immunocytochemistry/Immunofluorescence: ZMPSTE24 Antibody [ABIN250782] - analysis of ZMPSTE24 in A549 cells using anti-ZMPSTE24 antibody. Image from verified customer review. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-ZMPSTE24 Pab (ABIN389049) is used in Western blot to detect ZMPSTE24 in T-47D cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 11 bis 13 Tage
$468.05
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-ZMPSTE24 Pab (ABIN389048) is used in Western blot to detect ZMPSTE24 in mouse cerebellum tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB ZMPSTE24 Antibody (C-term) (ABIN1882012) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ZMPSTE24 antibody detected the ZMPSTE24 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185713 (0.5µg/ml) staining of Human Skin lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

Zmpste24 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Zinc Metalloproteinase, Ste24 Antikörper

  1. Human Polyclonal Zmpste24 Primary Antibody für ICC, IF - ABIN250782 : Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24. in The Biochemical journal 2005 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Zmpste24 Primary Antibody für WB - ABIN1882012 : Fontaine-Bisson, Alessi, Saut, Fumeron, Marre, Dutour, Badens, Levy, Tichet, Juhan-Vague, Trégouët, Balkau, Morange: Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study. in Journal of molecular medicine (Berlin, Germany) 2010 (PubMed)
    Show all 3 Pubmed References

  3. Polyclonal Zmpste24 Primary Antibody für WB - ABIN540233 : Young, Fong, Michaelis: Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis. in Journal of lipid research 2005 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal Zmpste24 Primary Antibody für IHC (p), WB - ABIN389048 : Kumagai, Kawamura, Yanagisawa, Komano: Identification of a human cDNA encoding a novel protein structurally related to the yeast membrane-associated metalloprotease, Ste24p. in Biochimica et biophysica acta 1999 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal Zmpste24 Primary Antibody für ELISA, WB - ABIN251680 : Fong, Frost, Meta, Qiao, Yang, Coffinier, Young: A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. in Science (New York, N.Y.) 2006 (PubMed)

  6. Human Polyclonal Zmpste24 Primary Antibody für IHC (p), WB - ABIN389049 : Moulson, Go, Gardner, van der Wal, Smitt, van Hagen, Miner: Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. in The Journal of investigative dermatology 2005 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Zinc Metalloproteinase, Ste24 Interaktionspartner

Human Zinc Metalloproteinase, Ste24 (Zmpste24) Interaktionspartner

  1. ZMPSTE24 is a downstream effector of IFITM3 (zeige IFITM3 Antikörper) and is important for interferon (zeige IFNA Antikörper)-induced transmembrane antiviral activity.

  2. ZMPSTE24 is an important element for innate host defense against a broad spectrum of pathogenic viruses.

  3. This case demonstrates that accumulation of prelamin A, independent of the loss of function of ZMPSTE24 metallopeptidase (zeige ECEL1 Antikörper) that catalyzes processing of prelamin A, can cause a progeroid disorder and that a cell biology assay could be used in precision medicine to identify a potential therapy.

  4. used a fluorogenic assay of the activity of purified ZMPSTE24 to demonstrate that HIV protease inhibitors directly inhibit the human enzyme in a manner indicative of a competitive mechanism

  5. the present study suggests that inhibition of ZMPSTE24 by both mutational and expressional pathways might together play a role in tumorigenesis of colorectal cancer and gastric cancer harboring microsatellite instability phenotype.

  6. results establish that the substrate profile of Ste24p is broader than anticipated, being more similar to that of the M16A protease family than that of the Rce1p CAAX protease with which it has been functionally associated

  7. ZMPSTE24 downregulation is a major contributor in VSMC dysfunctions resulting from LMNA (zeige LMNA Antikörper) mutations or PI treatments that could translate in early atherosclerosis at the clinical level.

  8. Here, we report on a familial c.50delA (p.Lys17Serfs*21) mutation of the ZMPSTE24 gene, causing RD in two siblings.

  9. complete loss-of-function of ZMPSTE24 leads to RD, whereas other less severe phenotypes are associated with at least one haploinsufficient allele.

  10. miR (zeige MLXIP Antikörper)-141-3p, which is overexpressed during senescence as a result of epigenetic regulation, is able to decrease ZMPSTE24 expression levels, and leads to an upregulation of prelamin A in human mesenchymal stem cells.

Mouse (Murine) Zinc Metalloproteinase, Ste24 (Zmpste24) Interaktionspartner

  1. ZMPSTE24 is a downstream effector of IFITM3 (zeige IFITM3 Antikörper) and is important for interferon (zeige IFNA Antikörper)-induced transmembrane antiviral activity.

  2. ZMPSTE24 is an important element for innate host defense against a broad spectrum of pathogenic viruses.

  3. we identified the abnormal lamin A (zeige LMNA Antikörper) (prelamin A), accompanied by a down-regulation of a lamin A (zeige LMNA Antikörper) processing enzyme (Zmpste24) in the kidney of the GMF (zeige GMFB Antikörper) transgenic mice

  4. In Zmpste24(-/-) mice, histone H4 (zeige HIST1H4H Antikörper) was hypoacetylated at a lysine 16 residue (H4K16), and this defect was attributed to the reduced association of a histone acetyltransferase (zeige HAT Antikörper), Mof (zeige KAT8 Antikörper), to the nuclear matrix.

  5. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

  6. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

  7. Zmpste24 has a role in processing of prelamin A and lack of Zmpste24 results in a brittle bone phenotype

  8. the progeria-like phenotypes caused by the lack of Zmpste24 in knockout mice is eliminated by heterozygosity for Lmna (zeige LMNA Antikörper)

  9. Lack of functional Zmpste24, a metalloproteinase responsible for the maturation of prelamin A, also results in progeroid phenotypes in mice

  10. Zmpste24 deficiency elicits a stress signalling pathway that is evidenced by a marked upregulation of p53 (zeige TP53 Antikörper) target genes, and accompanied by a senescence phenotype at the cellular level and accelerated ageing at the organismal level

Zinc Metalloproteinase, Ste24 (Zmpste24) Antigen-Profil

Protein Überblick

This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.

Genbezeichner und Symbole assoziert mit Zmpste24

  • zinc metallopeptidase STE24 (ZMPSTE24) Antikörper
  • zinc metallopeptidase STE24 L homeolog (zmpste24.L) Antikörper
  • zinc metallopeptidase STE24 (zmpste24) Antikörper
  • CAAX prenyl protease (zmpste24) Antikörper
  • Peptidase family M48 family protein (ATSTE24) Antikörper
  • zinc metallopeptidase STE24 (Zmpste24) Antikörper
  • zinc metallopeptidase, STE24 (Zmpste24) Antikörper
  • zinc metallopeptidase, STE24 homolog (zmpste24) Antikörper
  • A530043O15Rik Antikörper
  • D030046F19 Antikörper
  • DDBDRAFT_0189115 Antikörper
  • DDBDRAFT_0237846 Antikörper
  • DDB_0189115 Antikörper
  • DDB_0237846 Antikörper
  • F2N1.21 Antikörper
  • F2N1_21 Antikörper
  • Face-1 Antikörper
  • FACE1 Antikörper
  • fi45a02 Antikörper
  • HGPS Antikörper
  • MADB Antikörper
  • PRO1 Antikörper
  • STE24 Antikörper
  • Ste24p Antikörper
  • wu:fi45a02 Antikörper
  • zgc:55655 Antikörper

Bezeichner auf Proteinebene für Zmpste24

zinc metallopeptidase (STE24 homolog, S. cerevisiae) , zinc metallopeptidase (STE24 homolog) , zinc metallopeptidase STE24 homolog , zinc metalloproteinase STE24 homolog , CAAX prenyl protease 1 homolog , STE24 endopeptidase , zinc metalloproteinase , zinc metallopeptidase STE24 , CAAX prenyl protease 1 homolog-like , farnesylated proteins-converting enzyme 1 , prenyl protein-specific endoprotease 1 , zinc metalloproteinase Ste24 homolog , zinc metallopeptidase, STE24 homolog , zinc metalloproteinase, STE24 homolog , farnesylated-proteins converting enzyme 1 , zinc metalloproteinase (STE24 homolog, yeast)

GENE ID SPEZIES
419572 Gallus gallus
447784 Xenopus laevis
456790 Pan troglodytes
482460 Canis lupus familiaris
550009 Xenopus (Silurana) tropicalis
693765 Macaca mulatta
8627861 Dictyostelium discoideum AX4
100032108 Monodelphis domestica
100339077 Oryctolagus cuniculus
100404786 Callithrix jacchus
100445390 Pongo abelii
100475834 Ailuropoda melanoleuca
100557771 Anolis carolinensis
100580430 Nomascus leucogenys
828209 Arabidopsis thaliana
538104 Bos taurus
10269 Homo sapiens
313564 Rattus norvegicus
230709 Mus musculus
334380 Danio rerio
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