Zinc Fingers and Homeoboxes 1 Proteine (ZHX1)

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. Zusätzlich bieten wir Ihnen ZHX1 Antikörper (47) und ZHX1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ZHX1 11244 Q9UKY1
Maus ZHX1 ZHX1 22770 P70121
Ratte ZHX1 ZHX1 171159 Q8R515
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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ZHX1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,

Weitere Proteine zu Zinc Fingers and Homeoboxes 1 (ZHX1) Interaktionspartnern

Human Zinc Fingers and Homeoboxes 1 (ZHX1) Interaktionspartner

  1. ZHX1 expression is correlated with renal cell carcinoma (zeige MOK Proteine) progression and poor survival.

  2. ZHX1 was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1 (zeige EGR1 Proteine).

  3. together, this study demonstrates that ZHX1 plays crucial roles in the progression of glioblastoma, and its findings suggest that ZHX1 be viewed as a potential prognostic maker and therapeutic target of glioblastoma.

  4. High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved.

  5. miR (zeige MLXIP Proteine)-199a-3p may function as a novel tumor promoter in gastric cancer and its oncogenic activity may involve the direct targeting and inhibition of ZHX1

  6. Low expression of ZHX1 may be responsible for hepatocarcinogenesis.

  7. Study showed that ZHX1 is SUMOylated by Ubc9 (zeige UBE2I Proteine) with SUMO1 (zeige SUMO1 Proteine) at the sites K159, K454, and K626 and that the SUMOylation of ZHX1 regulated the stability, ubiquitination and transcriptional activity of ZHX1.

  8. This study characterized features of ZHX-1 involved in nuclear localization, dimerization, and transcriptional activity, and mapped these domains.

  9. a search of ZHX1-interacting proteins using a yeast two-hybrid system

  10. ZHX1 enhanced the transcriptional repression mediated by DNMT3B (zeige DNMT3B Proteine) when DNMT3B (zeige DNMT3B Proteine) is directly targeted to DNA. These results showed for the first the direct linkage between DNMT (zeige DNMT1 Proteine) and zinc-fingers homeoboxes protein, leading to enhanced gene silencing by DNMT3B (zeige DNMT3B Proteine)

Mouse (Murine) Zinc Fingers and Homeoboxes 1 (ZHX1) Interaktionspartner

ZHX1 Protein Überblick

Protein Überblick

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.

Genbezeichner und Symbole assoziert mit ZHX1

  • zinc fingers and homeoboxes 1 (ZHX1)
  • zinc fingers and homeoboxes 1 (zhx1)
  • zinc fingers and homeoboxes 1 (Zhx1)
  • 3110006I21Rik Protein
  • mKIAA4149 Protein
  • ZHX1 Protein

Bezeichner auf Proteinebene für ZHX1

zinc finger and homeodomain protein 1 , zinc fingers and homeoboxes 1 , zinc fingers and homeoboxes protein 1 , zinc fingers and homeobox 1 , zinc-fingers and homeoboxes 1 , Zinc fingers and homeoboxes protein 1

GENE ID SPEZIES
100442425 Pongo abelii
420347 Gallus gallus
475089 Canis lupus familiaris
704254 Macaca mulatta
782847 Bos taurus
100126068 Xenopus (Silurana) tropicalis
100558335 Anolis carolinensis
11244 Homo sapiens
22770 Mus musculus
171159 Rattus norvegicus
100984802 Pan paniscus
464368 Pan troglodytes
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