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Zinc Finger Protein 57 Proteine (ZFP57)

May be involved in transcriptional regulation..

alle Proteine anzeigen Gen GeneID UniProt
Human ZFP57 ZFP57 126295 Q68EA5
Maus ZFP57 ZFP57 22715 Q8C6P8
ZFP57 361783 A0JPK3
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Hefe Ratte His tag 1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.976,98 €
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ZFP57 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus)

Weitere Proteine zu Zinc Finger Protein 57 (ZFP57) Interaktionspartnern

Human Zinc Finger Protein 57 (ZFP57) Interaktionspartner

  1. ZNF424 protein may act as a transcriptional repressor that suppresses NFAT (zeige NFATC1 Proteine) and p21 (zeige CDKN1A Proteine) pathway to mediate cellular functions.

Mouse (Murine) Zinc Finger Protein 57 (ZFP57) Interaktionspartner

  1. another function of ZFP57 in early embryogenesis is to repress cis (zeige CISH Proteine)-acting regulatory elements whose activity is not yet required.

  2. Data show that ZFP57 binding is affected by single nucleotide polymorphism (SNPs) and closely associated TGCCGC motif sequences that are present at the target sites.

  3. Within established mouse imprinted clusters, ZFP57 specifically binds known or predicted imprinting control region elements, but does not interact with secondary somatically differentially methylated regions (DMRs) or germline DMRs that are not imprinting controlling.

  4. ZFP57 may modulate NOTCH (zeige NOTCH1 Proteine) signaling during cardiac development.

  5. Taken together, our results suggest that Nanog positively regulates Zfp57 expression in multiple types of cells.

  6. Mouse and human ZFP57 are orthologs despite relatively low sequence identity.

  7. Data suggest that Glu182 in the DNA binding site in zinc finger motif of Zfp57 plays important role in binding specificity and affinity for 5-carboxylcytosine and other cytosine analogs.

  8. the structure of the DNA-binding domain of Zfp57, consisting of two adjacent zinc fingers, in complex with fully methylated DNA

  9. ZFP57 may recruit DNA methyltransferases to its target regions to maintain DNA methylation (zeige HELLS Proteine) imprint, and this interaction is likely facilitated by KAP1/TRIM28/TIF1beta (zeige TRIM28 Proteine).

  10. In embryonic stem cells, ZFP57/KAP1 (zeige TRIM28 Proteine) recognize a methylated hexanucleotide to affect chromatin and DNA methylation (zeige HELLS Proteine) of imprinting control regions.

ZFP57 Protein Überblick

Protein Überblick

May be involved in transcriptional regulation.

Genbezeichner und Symbole assoziert mit Zinc Finger Protein 57 Proteine (ZFP57)

  • zinc finger protein 57 (ZNF57)
  • zinc finger protein 57 (Zfp57)
  • G19 Protein
  • Zfp-57 Protein
  • ZNF424 Protein

Bezeichner auf Proteinebene für Zinc Finger Protein 57 Proteine (ZFP57)

zinc finger protein 424 , zfp-57

GENE ID SPEZIES
126295 Homo sapiens
22715 Mus musculus
361783 Rattus norvegicus
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