Williams Beuren Syndrome Chromosome Region 22 Proteine (WBSCR22)

WBSCR22 encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. Zusätzlich bieten wir Ihnen WBSCR22 Antikörper (43) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
WBSCR22 114049 O43709
Maus WBSCR22 WBSCR22 66138 Q9CY21
Ratte WBSCR22 WBSCR22 368084  
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,90 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.606,83 €
Details

WBSCR22 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,

Weitere Proteine zu Williams Beuren Syndrome Chromosome Region 22 (WBSCR22) Interaktionspartnern

Human Williams Beuren Syndrome Chromosome Region 22 (WBSCR22) Interaktionspartner

  1. The localization of the TRMT112 (zeige TRMT112 Proteine) protein is determined by WBSCR22, and the WBSCR22-TRMT112 (zeige TRMT112 Proteine) complex is localized in the cell nucleus.

  2. DIMT1L (zeige DIMT1 Proteine) and WBSCR22-TRMT112 (zeige TRMT112 Proteine) are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity.

  3. Knockdown of Merm1/Wbscr22 attenuates sensitivity of H460 non-small cell lung cancer cells to SN-38 and 5-FU without alteration to p53 (zeige TP53 Proteine) expression levels.

  4. The key role of WBSCR22 in 40S subunit (zeige RPS21 Proteine) biogenesis is independent of its function as an RNA methyltransferase.

  5. WBSCR22 protein level is decreased in lymphoblastoid cell lines.

  6. Merm1 is a novel regulator of chromatin structure affecting GR recruitment and function

  7. Characterization of two novel genes, WBSCR20 (zeige NSUN5 Proteine) and WBSCR22, deleted in Williams-Beuren syndrome

WBSCR22 Protein Überblick

Protein Überblick

This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found.

Genbezeichner und Symbole assoziert mit WBSCR22

  • Williams Beuren syndrome chromosome region 22 (WBSCR22)
  • Williams Beuren syndrome chromosome region 22 (wbscr22)
  • williams Beuren syndrome chromosome region 22 (CpipJ_CPIJ001394)
  • williams Beuren syndrome chromosome region 22 (PAAG_00857)
  • williams Beuren syndrome chromosome region 22 (MCYG_07273)
  • williams Beuren syndrome chromosome region 22 (PGTG_07527)
  • williams Beuren syndrome chromosome region 22 (PGTG_12505)
  • Williams Beuren syndrome chromosome region 22 (LOC100226152)
  • Williams Beuren syndrome chromosome region 22 protein (LOC100341475)
  • Williams Beuren syndrome chromosome region 22 (Wbscr22)
  • 1110003N24Rik Protein
  • HASJ4442 Protein
  • HUSSY-3 Protein
  • MERM1 Protein
  • MGC82375 Protein
  • PP3381 Protein
  • WBMT Protein
  • zgc:162306 Protein

Bezeichner auf Proteinebene für WBSCR22

Williams Beuren syndrome chromosome region 22 protein , Williams Beuren syndrome chromosome region 22 , hypothetical protein LOC496966 , williams Beuren syndrome chromosome region 22 , Williams-Beuren candidate region putative methyltransferase , Williams-Beuren syndrome chromosomal region 22 protein , metastasis-related methyltransferase 1 , uncharacterized methyltransferase WBSCR22 , Williams-Beuren syndrome chromosomal region 22 protein homolog

GENE ID SPEZIES
431053 Gallus gallus
443795 Xenopus laevis
496966 Xenopus (Silurana) tropicalis
572367 Danio rerio
6032746 Culex quinquefasciatus
9100585 Paracoccidioides sp. 'lutzii' Pb01
9226796 Arthroderma otae CBS 113480
10534661 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10535199 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100226152 Taeniopygia guttata
100341475 Oryctolagus cuniculus
114049 Homo sapiens
66138 Mus musculus
513878 Bos taurus
368084 Rattus norvegicus
Ausgewählte Anbieter für WBSCR22 Proteine (WBSCR22)
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