anti-WD Repeat and FYVE Domain Containing 3 (WDFY3) Antikörper

WDFY3 encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
WDFY3 23001 Q8IZQ1
WDFY3 72145 Q6VNB8
WDFY3 305164  
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Top anti-WDFY3 Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-WDFY3 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-WDFY3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>Human Muscle 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EM, ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: WDFY3 Antibody [NBP1-03332] - FFPE section of human ovarian carcinoma. Immunohistochemistry-Paraffin: WDFY3 Antibody [NBP1-03332] - FFPE section of human glioblastoma dilution of 1:5,000 (0.2ug/ml). Detection: DAB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Maus Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged WDFY3 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (71.94 KDa) . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert WB WDFY3 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 10 bis 13 Tage
460,89 €
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Details

WDFY3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-WDFY3 Antikörper

  1. Human Polyclonal WDFY3 Primary Antibody für EM, ICC - ABIN315857 : Sommi, Necchi, Vitali, Montagna, De Luigi, Salmona, Ricci, Solcia: PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors. in PLoS ONE 2013 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal WDFY3 Primary Antibody für ELISA, WB - ABIN949075 : Orosco, Ross, Cates, Scott, Wu, Sohn, Pleasure, Pleasure, Adamopoulos, Zarbalis: Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. in Nature communications 2014 (PubMed)

  3. Cow (Bovine) Polyclonal WDFY3 Primary Antibody für WB - ABIN2784358 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen WDFY3 Interaktionspartner

Human WD Repeat and FYVE Domain Containing 3 (WDFY3) Interaktionspartner

  1. we demonstrate that normally ALFY attenuates the canonical Wnt (zeige WNT2 Antikörper) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 (zeige DVL3 Antikörper) and not of Dvl1 (zeige DVL1 Antikörper) or Dvl2 (zeige DVL2 Antikörper).

  2. ALFY binds selectively to LC3C (zeige MAP1LC3C Antikörper) and the GABARAPs through a LC3 (zeige MAP1LC3A Antikörper)-interacting region in its WD40 domain (zeige DCAF12L2 Antikörper).

  3. increasing Alfy-mediated protein degradation may be beneficial in some organs, but may be detrimental in others

  4. Data suggest that p62 (zeige GTF2H1 Antikörper) and ALFY interact to organize misfolded, ubiquitinated proteins into protein bodies that become degraded by autophagy.

  5. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.

  6. Alfy might target cytosolic protein aggregates for autophagic degradation.

Mouse (Murine) WD Repeat and FYVE Domain Containing 3 (WDFY3) Interaktionspartner

  1. Alfy translocalization likely is involved in the pathogenesis of amyotrophic lateral sclerosis.

  2. Wdfy3 is important in regulating neural progenitor divisions, neural migration, cerebral expansion and functional organization in the developing brain. Loss-of-function leads to pathological changes characteristic of autism spectrum disorders.

  3. gene expression profiling; in situ hybridization analysis revealed that the expressed BWF1 mRNA was restricted to the marginal region both in E14 (zeige NPAT Antikörper) and E16 (zeige SLC7A5 Antikörper) embryonic brain, but became diffuse after birth

WDFY3 Antigen-Profil

Protein Überblick

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Genbezeichner und Symbole assoziert mit WDFY3

  • WD repeat and FYVE domain containing 3 (WDFY3) Antikörper
  • WD repeat and FYVE domain-containing protein 3 (MGYG_03998) Antikörper
  • WD repeat and FYVE domain containing 3 (Wdfy3) Antikörper
  • 2610509D04Rik Antikörper
  • ALFY Antikörper
  • AW319683 Antikörper
  • B930017C24 Antikörper
  • Bchs Antikörper
  • BWF1 Antikörper
  • D5Ertd66e Antikörper
  • Ggtb3 Antikörper
  • mKIAA0993 Antikörper
  • ZFYVE25 Antikörper

Bezeichner auf Proteinebene für WDFY3

WD repeat and FYVE domain containing 3 , WD repeat and FYVE domain-containing protein 3 , autophagy-linked FYVE protein , beach domain, WD repeat and FYVE domain-containing protein 1 , galactosyltransferase 3 beta 1, 4

GENE ID SPEZIES
100157904 Sus scrofa
461201 Pan troglodytes
10029110 Arthroderma gypseum CBS 118893
422613 Gallus gallus
23001 Homo sapiens
487841 Canis lupus familiaris
537096 Bos taurus
72145 Mus musculus
305164 Rattus norvegicus
Ausgewählte Anbieter für anti-WDFY3 (WDFY3) Antikörper
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