Vaccinia Related Kinase 2 Proteine (VRK2)

VRK2 encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Zusätzlich bieten wir Ihnen VRK2 Antikörper (50) und VRK2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
VRK2 7444 Q86Y07
Maus VRK2 VRK2 69922 Q8BN21
Ratte VRK2 VRK2 360991  
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Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Baculovirus infected Insect Cells Human GST tag   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
413,60 €
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Insektenzellen Human GST tag   5 μg Anmelden zum Anzeigen 7 bis 8 Tage
537,60 €
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Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 7 bis 9 Tage
304,76 €
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VRK2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,

Weitere Proteine zu Vaccinia Related Kinase 2 (VRK2) Interaktionspartnern

Human Vaccinia Related Kinase 2 (VRK2) Interaktionspartner

  1. Reduced VRK2 mRNA levels are involved in the underlying mechanisms in schizophrenia spectrum disorders.

  2. These data support a model in which vaccinia virus B1 and human VRK2 share additional substrates important for the replication of cytoplasmic poxviruses.

  3. we replicated one known signal in PAX8 (zeige PAX8 Proteine) (2.6 minutes per allele, 95% CI [1.9, 3.2], P = 5.7x10-16) and identified and replicated two novel associations at VRK2 (2.0 minutes per allele, 95% CI [1.3, 2.7], P = 1.2x10-9; and 1.6 minutes per allele, 95% CI [1.1, 2.2], P = 7.6x10-9)

  4. The data provides further evidence for the genetic contributions of VRK2 rs2312147 to schizophrenia susceptibility especially in Europeans, while further replication analyses in Asian populations are still needed. [meta-analysis]

  5. Our data provide preliminary evidence that the VRK2 gene might play a major role in the development of SCZ in the Northwest Chinese Han population.

  6. data may provide evidence for the effect of VRK2 on WM connectivity in patients with schizophrenia

  7. Findings suggest that ubiquitin-specific protease 25 (USP25 (zeige USP25 Proteine)) as a VRK2 substrate that acts on TRiC (zeige MARVELD2 Proteine) deubiquitination.

  8. VRK2 is crucial to regulate the ubiquitination-proteosomal degradation of eukaryotic chaperonin TCP-1 ring complex

  9. Data from molecular dynamic simulations suggest that bivalent cations play key structural roles in stabilization of VRK1/VRK2; bivalent cations have no obvious effects on VRK3. These kinases are targets in search for antineoplastic agents. [REVIEW]

  10. Low levels of VRK2A causes an increase in mitochondrial Bax (zeige BAX Proteine) protein level, leading to an increase in the release of cytochrome C (zeige CYCS Proteine) and caspase (zeige CASP3 Proteine) activation, detected by PARP processing.

Mouse (Murine) Vaccinia Related Kinase 2 (VRK2) Interaktionspartner

VRK2 Protein Überblick

Protein Überblick

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit VRK2

  • vaccinia related kinase 2 (LOC100345223)
  • vaccinia related kinase 2 (VRK2)
  • vaccinia related kinase 2 (Vrk2)
  • 2810003O05Rik Protein
  • AI447698 Protein

Bezeichner auf Proteinebene für VRK2

vaccinia related kinase 2 , serine/threonine-protein kinase VRK2 , vaccinia virus B1R-related kinase 2 , vaccinia virus BIR kinase related kinase 2 , vaccinia-related kinase 2

GENE ID SPEZIES
100345223 Oryctolagus cuniculus
7444 Homo sapiens
69922 Mus musculus
360991 Rattus norvegicus
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