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The protein encoded by MAF is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Zusätzlich bieten wir Ihnen V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Antikörper (114) und V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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interplay between MATalpha1, c-Myc (zeige MYC ELISA Kits), and Maf proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis
MafB (zeige MAFB ELISA Kits) and c-Maf have different expression patterns in macrophages, suggesting differences in function.
HERC4 (zeige HERC4 ELISA Kits) mediates c-Maf ubiquitination and delays growth of multiple myeloma.
Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin (zeige CRYAA ELISA Kits) both directly and indirectly via up-regulation of c-Maf.
Tec (zeige NR4A3 ELISA Kits) enhances c-Maf-dependent IL-4 (zeige IL4 ELISA Kits) promoter activity. This effect of Tec (zeige NR4A3 ELISA Kits) is counteracted by Ptpn22 (zeige PTPN22 ELISA Kits), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf thereby attenuating its transcriptional activity.
endogenous small-Maf factors negatively regulate beta-cell function by competing for MafA (zeige MAFA ELISA Kits) binding, and thus, the inhibition of small-Maf activity can improve beta-cell function
The melanoma microenvironment contributes to skewing of CD8 (zeige CD8A ELISA Kits) T cell differentiation programs, in part by TGFbeta (zeige TGFB1 ELISA Kits)/IL-6 (zeige IL6 ELISA Kits)-mediated induction of Maf.
Sox5 (zeige SOX5 ELISA Kits) physically associates with c-Maf via the HMG (zeige SSRP1 ELISA Kits) domain of Sox5 (zeige SOX5 ELISA Kits) and DNA-binding domain of c-Maf, and Sox5 (zeige SOX5 ELISA Kits) together with c-Maf directly activates the promoter of RORgammat in CD4 (zeige CD4 ELISA Kits)(+) T cells.
KLF13 (zeige KLF13 ELISA Kits) directly binds to IL-4 (zeige IL4 ELISA Kits) promoter regions and synergizes with c-Maf to positively regulate IL-4 (zeige IL4 ELISA Kits) expression.
The p53 (zeige TP53 ELISA Kits) transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf.
The interaction between c-Maf and RORgammat, and Blimp-1 (zeige PRDM1 ELISA Kits).
Polymorphisms rs9939609 (FTO (zeige FTO ELISA Kits) gene) and rs1424233 (MAF gene) were genotyped using allelic discrimination assays in a prospective multicenter cohort study; these polymorphisms did not show associations with birth weight, BMI and Ponderal Index at discharge, and weight gain, neither testing for a dominant, additive nor for a recessive model.
this study shows that genes associated with MAF-binding enhancers are suppressed in macrophages isolated from rheumatoid-arthritis patients, revealing a disease-associated signature of IFN-gamma (zeige IFNG ELISA Kits)-mediated repression
Our results argued that increased expression of sIL6R from myeloid cells and subsequent c-Maf induction were adverse events for counteracting tumor-specific Th1 (zeige TH1L ELISA Kits) generation. Overall, this work provides a mechanistic rationale for sIL6R targeting to improve the efficacy of T-cell-mediated cancer immunotherapy
These results define the role of MAF and GSK3 (zeige GSK3b ELISA Kits) in the resistance of t(14;16) multiple myeloma to proteasome inhibitors.
Epidermal differentiation gene regulatory networks are controlled by MAF and MAFB (zeige MAFB ELISA Kits).
Findings implicate the strong effects of ROS (zeige ROS1 ELISA Kits) on multiple stem cell functions with a central role for c-Maf in stem cell senescence.
Data suggest miR (zeige MLXIP ELISA Kits)-1290 as the new oncomiR involved in laryngeal squamous cell carcinoma pathogenesis probably through downregulation of its target genes MAF and ITPR2 (zeige ITPR2 ELISA Kits).
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
, V-maf musculoaponeurotic fibrosarcoma oncogene homolog
, c-Maf long form
, proto-oncogene c-maf
, transcription factor Maf
, Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
, T lymphocyte c-maf long form
, c-maf proto-oncogene
, proto-oncogene c-Maf
, transcription factor Maf-2
, Proto-oncogene c-maf