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anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Antikörper

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002. Zusätzlich bieten wir Ihnen V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAFA 50928 O88713
MAFA 58975 Q64335
MAFA 389692 Q8NHW3
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Top anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of MAFA Antibody (C-term) (ABIN653391) in WiDr cell line lysates (35 µg/lane). MAFA (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of MAFA Antibody (C-term) in WiDr cell line lysates (35ug/lane). MAFA (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of MAFA Antibody (Center) in mouse spleen tissue lysates (35ug/lane). MAFA (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of MAFA Antibody (C-term) in K562 cell line lysates (35ug/lane). This demonstrates the MAFA antibody detected the MAFA protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of MAFA Antibody (Center) (ABIN653392) in mouse spleen tissue lysates (35 µg/lane). MAFA (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ChIP, GS, ICC, IHC (fro), IF, IHC (p), IHC, WB Electrophoretic Mobility Shift of MafA, MafB and c-Maf. Samples: Nuclear extract (6 ug) from HeLa cells transfected with MafA, MafB or c-Maf expression constructs. Antibodies: Affinity purified anti-MafA antibody ABIN152904, anti-MafB antibody NB 600-266 or anti-c-Maf antibody ABIN153206. Binding of MafA to the enhancer region of the endogenous insulin gene. Samples: Immunoprecipitated cross-linked DNA from betaTC-3 cells was analyzed by PCR. As controls, reactions were run with no DNA, with input chromatin, with DNA obtained after precipitation with rabbit IgG or without antibody (lanes 1 through 5, respectively). Antibody: Affinity purified rabbit anti-MafA antibody (ABIN152904). 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
463,75 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunofluorescence: MafA Antibody [NBP1-00121] - analysis of MafA in 8-week old mouse pancretic cryosection using anti-MafA antibody (red). Image from verified customer review. Immunohistochemistry: MafA Antibody [NBP1-00121] - Sample: FFPE section of mouse pancreatic islet. Antibody: Affinity purified rabbit anti-MafA (Cat. No. NBP1-00121) used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
512,50 €
Details
Maus Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details

MAFA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,


Rat (Rattus)


Human ,
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Am meisten referenzierte anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Antikörper

  1. Human Polyclonal MAFA Primary Antibody für ChIP, GS - ABIN152904 : Wang, Torres-Gonzalez, Tripathy, Botolin, Christian, Jump: Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition. in Journal of lipid research 2008 (PubMed)
    Zeige alle 38 Referenzen für ABIN152904

  2. Human Polyclonal MAFA Primary Antibody für EIA, WB - ABIN953282 : Garin, Martinez, de las Heras, Perez-Nanclares, Castano, Perez de Nanclares: Mutations in MAFA and IAPP are not a common cause of monogenic diabetes. in Diabetic medicine : a journal of the British Diabetic Association 2009 (PubMed)
    Zeige alle 5 Referenzen für ABIN953282

  3. Human Polyclonal MAFA Primary Antibody für EIA, WB - ABIN953280 : Lecoin, Rocques, El-Yakoubi, Ben Achour, Larcher, Pouponnot, Eychène: MafA transcription factor identifies the early ret-expressing sensory neurons. in Developmental neurobiology 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN953280

  4. Human Polyclonal MAFA Primary Antibody für EIA, WB - ABIN953281 : Martin, Flemming, Wang, Oeser, OBrien: Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression. in Journal of molecular endocrinology 2008 (PubMed)
    Zeige alle 3 Referenzen für ABIN953281

  5. Human Polyclonal MAFA Primary Antibody für WB - ABIN2783128 : Matsuoka, Kaneto, Stein, Miyatsuka, Kawamori, Henderson, Kojima, Matsuhisa, Hori, Yamasaki: MafA regulates expression of genes important to islet beta-cell function. in Molecular endocrinology (Baltimore, Md.) 2007 (PubMed)

  6. Human Polyclonal MAFA Primary Antibody für WB - ABIN653392 : Kondo, El Khattabi, Nishimura, Laybutt, Geraldes, Shah, King, Bonner-Weir, Weir, Sharma: p38 MAPK is a major regulator of MafA protein stability under oxidative stress. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

Weitere Antikörper gegen V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Interaktionspartner

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Interaktionspartner

  1. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in type 2 diabetes.

  2. These findings demonstrate that regulation of monoamine levels by Mao (zeige MAO Antikörper) activity in beta cells is pivotal for physiological insulin (zeige INS Antikörper) secretion and that loss of MaoB (zeige MAOB Antikörper) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  3. is necessary for the maintenance of normal insulin (zeige INS Antikörper) levels even in embryos.

  4. endogenous small-Maf (zeige MAF Antikörper) factors negatively regulate beta-cell function by competing for MafA binding, and thus, the inhibition of small-Maf (zeige MAF Antikörper) activity can improve beta-cell function

  5. Data, including data from studies using transgenic/knockout mice, confirm the expression of Mafa and Mafb (zeige MAFB Antikörper) is specific to insulin (zeige INS Antikörper)-secreting cells of the pancreas.

  6. These results suggest that MafA regulates the postnatal proliferation of beta-cells via prolactin (zeige PRL Antikörper) signaling.

  7. This finding provides a rationale for the reciprocal expression of KLRG1 (zeige KLRG1 Antikörper) and CD103 (zeige ITGAE Antikörper) in different CD8 (zeige CD8A Antikörper)(+) T-cell subsets.

  8. results illustrate how consequential the reduction in Mafa activity is to islet beta-cell function under pathophysiological conditions.

  9. Cytotoxic KLRG1 (zeige KLRG1 Antikörper)-expressed CD8 (zeige CD8A Antikörper) effector cells and defective T regulatory cells cause murine autoimmune cholangitis.

  10. KLRG1 (zeige KLRG1 Antikörper)(+) iNKT cells coexpressing CD49d and granzyme A (zeige GZMA Antikörper) persisted for several months and displayed a potent secondary response to cognate antigen.

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Interaktionspartner

  1. Pdx1 (zeige PDX1 Antikörper) and MafA (zeige KLRG1 Antikörper) play crucial roles in the pancreas and maintain mature beta-cell function. Our results showed that the expression of Pdx1 (zeige PDX1 Antikörper) and MafA (zeige KLRG1 Antikörper) were significantly upregulated after a sleeve gastrectomy for morbid obesity.

  2. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in patients with type 2 diabetes.

  3. These findings demonstrate that regulation of monoamine levels by Mao (zeige MAO Antikörper) activity in beta cells is pivotal for physiological insulin (zeige INS Antikörper) secretion and that loss of MaoB (zeige MAOB Antikörper) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  4. MAFA (zeige KLRG1 Antikörper), MAFB (zeige MAFB Antikörper), NKX6.1 (zeige NKX6-1 Antikörper), and PDX1 (zeige PDX1 Antikörper) activity provides a gauge of islet beta cell function, with loss of MAFA (zeige KLRG1 Antikörper) (and/or MAFB (zeige MAFB Antikörper)) representing an early indicator of beta cell inactivity

  5. Loss of MAFA (zeige KLRG1 Antikörper) expression is associated with insulinoma (zeige RPS15 Antikörper).

  6. MAFA (zeige KLRG1 Antikörper) nuclear expression in pancreatic alpha and beta cells, and the percentage of alpha cells expressing PAX4 (zeige PAX4 Antikörper) are altered in patients with type 2 diabetes.

  7. under oxidative and nonoxidative conditions p38 MAPK (zeige MAPK14 Antikörper) directly binds to MafA (zeige KLRG1 Antikörper) and triggers MafA (zeige KLRG1 Antikörper) degradation via ubiquitin proteasomal pathway.

  8. Beta cell nuclear MafA (zeige KLRG1 Antikörper) is markedly decreased in humans with type 2 diabetes, which may contribute to impaired beta cell dysfunction.

  9. Combined transfection of the three transcriptional factors, PDX-1 (zeige PDX1 Antikörper), NeuroD1 (zeige NEUROD1 Antikörper), and MafA (zeige KLRG1 Antikörper), causes differentiation of bone marrow mesenchymal stem cells into insulin (zeige INS Antikörper)-producing cells

  10. Data suggest that MafA (zeige KLRG1 Antikörper) plays a novel role in the reprogramming of stem cells into pancreatic beta-progenitors, promotes the islet-like characteristics of PDMSCs, as well as functionally regulation of blood glucose levels in transplanted grafts.

V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Antigen-Profil

Protein Überblick

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS\; MIM 176730) (Olbrot et al., 2002

Genbezeichner und Symbole assoziert mit MAFA

  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1) Antikörper
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (mafa) Antikörper
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene A (Mafa) Antikörper
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) Antikörper
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) (Mafa) Antikörper
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) Antikörper
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) (mafa) Antikörper
  • 2F1-Ag Antikörper
  • hMafA Antikörper
  • L-MAF Antikörper
  • MAFA Antikörper
  • MAFA-L Antikörper
  • mafl Antikörper
  • RGD1562627 Antikörper
  • RIPE3b1 Antikörper
  • SMaf1 Antikörper

Bezeichner auf Proteinebene für MAFA

killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , mast cell function-associated antigen , v-maf musculoaponeurotic fibrosarcoma oncogene homolog A , Transcription factor MafA , leucine zipper transcription factor , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A , pancreatic beta-cell-specific transcriptional activator , transcription factor MafA , transcription factor RIPE3b1 , Mafa homolog , V-maf musculoaponeurotic fibrosarcoma oncogene homolog A , bZIP transcription factor L-Maf , lens-specific Maf , somite Maf1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein L

GENE ID SPEZIES
50928 Mus musculus
58975 Rattus norvegicus
613050 Xenopus (Silurana) tropicalis
366949 Rattus norvegicus
389692 Homo sapiens
378435 Mus musculus
395881 Gallus gallus
100000492 Danio rerio
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