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The protein encoded by MAF is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Zusätzlich bieten wir Ihnen V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Kits (22) und V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 115 products:
Mouse (Murine) Polyclonal MAF Primary Antibody für ChIP, ICC - ABIN4285662
Nishimura, Kondo, Salameh, El Khattabi, Dodge, Bonner-Weir, Sharma: A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. in Developmental biology 2006
Show all 5 Pubmed References
Cow (Bovine) Polyclonal MAF Primary Antibody für IHC, IHC (p) - ABIN4285665
Hansen, Henderson, Lagos, Nikitenko, Coulter, Roberts, Gratrix, Plaisance, Renne, Bower, Kellam, Boshoff: KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. in Genes & development 2010
Show all 2 Pubmed References
Human Monoclonal MAF Primary Antibody für ELISA, WB - ABIN517678
Moreaux, Hose, Jourdan, Reme, Hundemer, Moos, Robert, Moine, De Vos, Goldschmidt, Klein: TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines. in Haematologica 2007
c-Maf is a critical transcription factor regulating T-cell specialization in mice, essential for generation of both RORgammat(+) Tregs and T follicular regulatory cells, but not for adipose-resident Tregs. c-Maf is induced in Tregs by IL-6 (zeige IL6 Antikörper) and TGF-beta (zeige TGFB1 Antikörper).
interplay between MATalpha1, c-Myc (zeige MYC Antikörper), and Maf proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis
MafB (zeige MAFB Antikörper) and c-Maf have different expression patterns in macrophages, suggesting differences in function.
HERC4 (zeige HERC4 Antikörper) mediates c-Maf ubiquitination and delays growth of multiple myeloma.
Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin (zeige CRYAA Antikörper) both directly and indirectly via up-regulation of c-Maf.
Tec (zeige NR4A3 Antikörper) enhances c-Maf-dependent IL-4 (zeige IL4 Antikörper) promoter activity. This effect of Tec (zeige NR4A3 Antikörper) is counteracted by Ptpn22 (zeige PTPN22 Antikörper), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf thereby attenuating its transcriptional activity.
endogenous small-Maf factors negatively regulate beta-cell function by competing for MafA (zeige MAFA Antikörper) binding, and thus, the inhibition of small-Maf activity can improve beta-cell function
The melanoma microenvironment contributes to skewing of CD8 (zeige CD8A Antikörper) T cell differentiation programs, in part by TGFbeta (zeige TGFB1 Antikörper)/IL-6 (zeige IL6 Antikörper)-mediated induction of Maf.
Sox5 (zeige SOX5 Antikörper) physically associates with c-Maf via the HMG (zeige SSRP1 Antikörper) domain of Sox5 (zeige SOX5 Antikörper) and DNA-binding domain of c-Maf, and Sox5 (zeige SOX5 Antikörper) together with c-Maf directly activates the promoter of RORgammat in CD4 (zeige CD4 Antikörper)(+) T cells.
KLF13 (zeige KLF13 Antikörper) directly binds to IL-4 (zeige IL4 Antikörper) promoter regions and synergizes with c-Maf to positively regulate IL-4 (zeige IL4 Antikörper) expression.
The interaction between c-Maf and RORgammat, and Blimp-1 (zeige PRDM1 Antikörper).
Polymorphisms rs9939609 (FTO (zeige FTO Antikörper) gene) and rs1424233 (MAF gene) were genotyped using allelic discrimination assays in a prospective multicenter cohort study; these polymorphisms did not show associations with birth weight, BMI and Ponderal Index at discharge, and weight gain, neither testing for a dominant, additive nor for a recessive model.
this study shows that genes associated with MAF-binding enhancers are suppressed in macrophages isolated from rheumatoid-arthritis patients, revealing a disease-associated signature of IFN-gamma (zeige IFNG Antikörper)-mediated repression
Our results argued that increased expression of sIL6R from myeloid cells and subsequent c-Maf induction were adverse events for counteracting tumor-specific Th1 (zeige TH1L Antikörper) generation. Overall, this work provides a mechanistic rationale for sIL6R targeting to improve the efficacy of T-cell-mediated cancer immunotherapy
These results define the role of MAF and GSK3 (zeige GSK3b Antikörper) in the resistance of t(14;16) multiple myeloma to proteasome inhibitors.
Epidermal differentiation gene regulatory networks are controlled by MAF and MAFB (zeige MAFB Antikörper).
Findings implicate the strong effects of ROS (zeige ROS1 Antikörper) on multiple stem cell functions with a central role for c-Maf in stem cell senescence.
Data suggest miR (zeige MLXIP Antikörper)-1290 as the new oncomiR involved in laryngeal squamous cell carcinoma pathogenesis probably through downregulation of its target genes MAF and ITPR2 (zeige ITPR2 Antikörper).
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
, V-maf musculoaponeurotic fibrosarcoma oncogene homolog
, c-Maf long form
, proto-oncogene c-maf
, transcription factor Maf
, Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
, T lymphocyte c-maf long form
, c-maf proto-oncogene
, proto-oncogene c-Maf
, transcription factor Maf-2
, Proto-oncogene c-maf