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Uroplakin 2 Proteine (UPK2)

UPK2 encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. Zusätzlich bieten wir Ihnen Uroplakin 2 Antikörper (13) und Uroplakin 2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
UPK2 7379 O00526
Maus UPK2 UPK2 22269  
Ratte UPK2 UPK2 689093  
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Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
523,81 €
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HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
285,71 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
457,14 €
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UPK2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,

Am meisten referenzierte Uroplakin 2 Proteine

  1. Human Uroplakin 2 Protein expressed in Escherichia coli (E. coli) - ABIN1098745 : Jenkins, Bitner-Glindzicz, Malcolm, Allison, de Bruyn, Flanagan, Thomas, Belk, Feather, Bingham, Southgate, Woolf: Mutation analyses of Uroplakin II in children with renal tract malformations. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 (PubMed)

Weitere Proteine zu Uroplakin 2 (UPK2) Interaktionspartnern

Human Uroplakin 2 (UPK2) Interaktionspartner

  1. These results suggest that whereas GATA-3 and uroplakin II may be most useful in the diagnosis of urothelial carcinoma metastasis, p40 may be additionally suited as a prognostic marker.

  2. UPII, GATA3, and p40, when used in combination, are highly sensitive in the differential diagnosis of invasive urothelial carcinoma.

  3. UPII was highly specific/moderately sensitive for urothelial carcinoma. May be a potentially useful marker to identify urothelial lineage and help distinguish UC from prostate cancer or, in conjunction with GATA3 (zeige GATA3 Proteine), from metastatic breast cancer.

  4. UPII demonstrates a significantly higher sensitivity than UPIII (zeige UPK3A Proteine) in conventional and variant urothelial carcinomas

  5. Uroplakin II antibody BC21 demonstrated superior sensitivity and specificity in urothelial carcinoma, compared with uroplakin III (zeige UPK3A Proteine), suggesting an advantage in differential diagnosis of urothelial carcinoma and in the detection of tumors of unknown origin.

  6. combination of prostate stem cell antigen (zeige PSCA Proteine) enhancer and uroplakin II promoter is feasible in constructing bladder cancer-specific vectors

  7. study offers no definitive support for uroplakin II mutations causing human renal tract malformations

Mouse (Murine) Uroplakin 2 (UPK2) Interaktionspartner

  1. The despites a lower level of expression, UPII maintain its plaque association in urothelial preneoplastic lesions.

  2. Bladder-specific autoimmune response sufficient to induce inflammation and interstitial cystitis occurs in mice following immunization with recombinant murine UPK2.

  3. The UPII knockout abolished plaque formation, indicating that both uroplakin heterodimers (UPIa (zeige UPK1A Proteine)/II and UPIb (zeige UPK1B Proteine)/III or IIIb) are required for plaque assembly.

Pig (Porcine) Uroplakin 2 (UPK2) Interaktionspartner

  1. HNF4 (zeige HNF4A Proteine) positively regulates pUPII gene promoter activity.

Uroplakin 2 (UPK2) Protein Überblick

Protein Überblick

This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.

Genbezeichner und Symbole assoziert mit Uroplakin 2 Proteine (UPK2)

  • uroplakin 2 (UPK2)
  • uroplakin 2 (upk2)
  • uroplakin 2 (Upk2)
  • AW491716 Protein
  • UP2 Protein
  • UPII Protein
  • UPK2 Protein

Bezeichner auf Proteinebene für Uroplakin 2 Proteine (UPK2)

uroplakin 2 , uroplakin II , uroplakin-2 , UP2 , UPII

GENE ID SPEZIES
610673 Canis lupus familiaris
707184 Macaca mulatta
100216448 Xenopus (Silurana) tropicalis
7379 Homo sapiens
22269 Mus musculus
689093 Rattus norvegicus
281569 Bos taurus
397075 Sus scrofa
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