anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) Antikörper

The protein encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. Zusätzlich bieten wir Ihnen UBA1 Kits (11) und UBA1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBA1 7317 P22314
UBA1 22201 Q02053
UBA1 314432 Q5U300
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Top anti-UBA1 Antikörper auf antikoerper-online.de

Showing 10 out of 86 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-UBA1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of UBA1 expression in rat liver extract (lane 1), mouse liver extract (lane 2), mouse testis extract (lane 3) and HELA whole cell lysates (lane 4). UBA1 at 117KD was detected using rabbit anti- UBA1 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB UBA1 Antibody (N-term) (ABIN658476) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the UBA1 antibody detected the UBA1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Hund Kaninchen Unkonjugiert EIA, IHC (p), WB   0.5 mg Anmelden zum Anzeigen 12 bis 15 Tage
$728.64
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$476.15
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with E1 Ubiquitin Activating Enzyme Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Maus Unkonjugiert ELISA, IP, WB Human UBE1 / UBA1 Western blot (WB) 14049 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$218.90
Details

UBA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-UBA1 Antikörper

  1. Cow (Bovine) Polyclonal UBA1 Primary Antibody für WB - ABIN2774233 : Ramser, Ahearn, Lenski, Yariz, Hellebrand, von Rhein, Clark, Schmutzler, Lichtner, Hoffman, Meindl, Baumbach-Reardon: Rare missense and synonymous variants in UBE1 are associated with X-linked infantile spinal muscular atrophy. in American journal of human genetics 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen UBA1 Interaktionspartner

Human Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) Interaktionspartner

  1. recent findings put UBA1 at the center of cellular homeostasis and neurodegeneration [review]

  2. A ubiquitin shuttle DC-UbP reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 (zeige USP5 Antikörper) enzymes.

  3. Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 (zeige UBD Antikörper) targets it for proteasomal degradation

  4. Ubiquitin-activating enzyme is necessary for 17beta-estradiol-induced breast cancer cell proliferation and migration.

  5. Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 and Uba6 (zeige UBA6 Antikörper).

  6. Decrease in free ubiquitin levels under stress allows NEDD8 (zeige NEDD8 Antikörper) to be conjugated through Ube1.

  7. UBA1 knockdown impairs formation of ubiquitin conjugates at DNA double-strand breaks.

  8. Data show that largazole and ester/keto analogs inhibit ubiquitin E1 activation.

  9. Ubiquitin and UBE1 are upregulated in tic epilepsy.

  10. In conclusion, nUBE1L is a novel human E1 like gene highly expressed in adult testis, which plays key role in ubiquitin system, and accordingly influences spermatogenesis and male fertility.

Mouse (Murine) Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) Interaktionspartner

  1. Inhibition of ubiquitin-activating enzyme E1 (Ube1) increases the levels of high- molecular weight mouse Htt (zeige HTT Antikörper) in relatively unaffected tissues, declining in the nuclear fraction with age.

  2. Dysregulation of UBA1 and subsequent ubiquitination pathways led to beta-catenin (zeige CTNNB1 Antikörper) accumulation in a model of spinal muscular atrophy.

  3. These data suggest that Cys (zeige DNAJC5 Antikörper)-278 can affect Ub charging through a change in the structural conformation of UBA1, not through direct interaction at the UBA1-Ub interface.

  4. biochemical and crystallographic characterization of the two half-domains and the crystal structure of the larger, second catalytic cysteine half-domain of mouse ubiquitin-activating enzyme

UBA1 Antigen-Profil

Protein Überblick

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.

Genbezeichner und Symbole assoziert mit UBA1

  • ubiquitin activating enzyme E1 (uae1) Antikörper
  • ubiquitin-like modifier activating enzyme 1 S homeolog (uba1.S) Antikörper
  • ubiquitin-like modifier activating enzyme 1 L homeolog (uba1.L) Antikörper
  • ubiquitin-like modifier activating enzyme 1 (uba1) Antikörper
  • Ubiquitin-conjugating enzyme E1 (GL50803_4083) Antikörper
  • Ubiquitin-conjugating enzyme E1 (GL50803_10661) Antikörper
  • ubiquitin like modifier activating enzyme 1 (UBA1) Antikörper
  • ubiquitin-like modifier activating enzyme 1 (Uba1) Antikörper
  • ubiquitin-like modifier activating enzyme 2 (Uba2) Antikörper
  • A1S9 Antikörper
  • A1S9T Antikörper
  • A1ST Antikörper
  • AA986091 Antikörper
  • AMCX1 Antikörper
  • Arx Antikörper
  • DDBDRAFT_0190927 Antikörper
  • DDBDRAFT_0220497 Antikörper
  • DDB_0190927 Antikörper
  • DDB_0220497 Antikörper
  • GXP1 Antikörper
  • POC20 Antikörper
  • Sae2 Antikörper
  • Sbx Antikörper
  • SMAX2 Antikörper
  • UBA1 Antikörper
  • UBA1A Antikörper
  • uba1b Antikörper
  • ube Antikörper
  • Ube-1 Antikörper
  • UBE1 Antikörper
  • Ube1x Antikörper
  • Ubl1a2 Antikörper
  • Uble1b Antikörper
  • wu:fa01e08 Antikörper
  • wu:fb30f01 Antikörper
  • wu:fi21c11 Antikörper
  • wu:fj14g11 Antikörper
  • zgc:66143 Antikörper

Bezeichner auf Proteinebene für UBA1

ubiquitin-activating enzyme E1 , ubiquitin activating enzyme , fb30f01 , ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) , ubiquitin-like modifier-activating enzyme 1 , Ubiquitin-conjugating enzyme E1 , A1S9T and BN75 temperature sensitivity complementing , POC20 centriolar protein homolog , UBA1, ubiquitin-activating enzyme E1 homolog A , ubiquitin-activating enzyme E1, Chr X , SUMO-activating enzyme subunit 2 , SUMO1 activating enzyme subunit 2 , Sumo-1 activating enzyme subunit 2 , anthracycline-associated resistance ARX , ubiquitin-like 1 (sentrin) activating enzyme E1B , ubiquitin-like 1 (sentrin) activating enzyme subunit 2 , ubiquitin-like 1-activating enzyme E1B

GENE ID SPEZIES
8617637 Dictyostelium discoideum AX4
379877 Xenopus laevis
398370 Xenopus laevis
406335 Danio rerio
5700601 Giardia lamblia ATCC 50803
5700939 Giardia lamblia ATCC 50803
7317 Homo sapiens
22201 Mus musculus
480896 Canis lupus familiaris
314432 Rattus norvegicus
282869 Bos taurus
100009225 Oryctolagus cuniculus
50995 Mus musculus
Ausgewählte Anbieter für anti-UBA1 (UBA1) Antikörper
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