Ubiquitin Fusion Degradation Protein 1 Homolog Proteine (UFD1L)

The protein encoded by UFD1L forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. Zusätzlich bieten wir Ihnen Ubiquitin Fusion Degradation Protein 1 Homolog Antikörper (92) und Ubiquitin Fusion Degradation Protein 1 Homolog Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
UFD1L 22230 P70362
UFD1L 7353 Q92890
UFD1L 84478 Q9ES53
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,817.83
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Hefe Caenorhabditis elegans His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,927.83
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Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$510.36
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Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
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UFD1L Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)
Human , , ,
, ,
Rat (Rattus) ,

Weitere Proteine zu Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Interaktionspartnern

Caenorhabditis elegans (C. elegans) Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Interaktionspartner

  1. These findings identified a role for CDC-48(UFD-1/NPL-4) in DNA replication, which is important for cell cycle progression and genome stability.

Mouse (Murine) Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Interaktionspartner

  1. The study revealed a regulatory role of the p97 (zeige EIF4G2 Proteine)-Npl4-Ufd1 complex in regulating a partial degradation of the NF-kappaB (zeige NFKB1 Proteine) subunit p100 (zeige PATL2 Proteine).

  2. the p97-Ufd1-Npl4 complex couples ubiquitinated IP(3) receptors to proteasomal degradation and, thus, plays a key role in IP(3) receptor processing

  3. structural analysis of the p97 (zeige EIF4G2 Proteine)-Npl4-Ufd1 interface

Human Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Interaktionspartner

  1. The study revealed a regulatory role of the p97 (zeige EIF4G2 Proteine)-Npl4-Ufd1 complex in regulating a partial degradation of the NF-kappaB (zeige NFKB1 Proteine) subunit p100 (zeige CUX1 Proteine).

  2. p97-Ufd1-Npl4 is an integral part of G2/M checkpoint signaling and thereby suppresses chromosome instability.

  3. Data indicate that the p97-UFD1L-NPL4 protein complex specifically associates with ubiquitinated IkappaBalpha via the interactions between p97 and the SCF(beta-TRCP) ubiquitin ligase.

  4. This study demonistrated that UFD1L may participate in the core cognitive deficits observed in schizophrenia.

  5. In coordination with the P97 (zeige EIF4G2 Proteine)-UFD1-NPL4 complex (P97 (zeige EIF4G2 Proteine)(UFD1/NPL4)), NUB1L promotes transfer of NEDD8 (zeige NEDD8 Proteine) to proteasome for degradation.

  6. increased corpus callosum volume in children with 22q11DS is associated with UFD1L polymorphism.

  7. Data indicate that Npl4-Ufd1 heterodimer is required for VCP (zeige vcp Proteine)-FAF1 (zeige FAF1 Proteine) interaction.

  8. Data establish Cdc48/p97 (zeige vcp Proteine)-Ufd1-Npl4 as a crucial negative regulator of Aurora B (zeige AURKB Proteine) early in mitosis of human somatic cells and suggest that the activity of Aurora B (zeige AURKB Proteine) on chromosomes needs to be restrained to ensure faithful chromosome segregation.

  9. Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control

  10. This study suggested that AA genotype of UFD1L gene, which is involved in neurodevelopmental processes, may contribute to early-onset schizophrenia. Therefore, rs5992403 polymorphism may not be a risk factor for schizophrenia.

Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Protein Überblick

Protein Überblick

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Genbezeichner und Symbole assoziert mit UFD1L

  • ubiquitin fusion degradation 1 like (yeast) (UFD1L)
  • ubiquitin recognition factor in ER associated degradation 1 (UFD1)
  • ubiquitin recognition factor in ER associated degradation 1 S homeolog (ufd1.S)
  • ubiquitin recognition factor in ER associated degradation 1 (ufd1)
  • ubiquitin fusion degradation protein 1 homolog (EHI_125920)
  • ubiquitin fusion degradation 1 like (Ufd1l)
  • ubiquitin fusion degradation protein 1 homolog (LOC100166745)
  • ubiquitin fusion degradation protein 1 homolog (LOC100635687)
  • ubiquitin fusion degradation protein 1 homolog (LOC100648660)
  • Ubiquitin Fusion Degradation (yeast UFD homolog) (ufd-1)
  • ubiquitin recognition factor in ER-associated degradation 1 (Ufd1)
  • ubiquitin recognition factor in ER associated degradation 1 (Ufd1)
  • ubiquitin recognition factor in ER associated degradation 1 (ufd1l)
  • UFD1 Protein
  • wu:fc55f04 Protein
  • zgc:92341 Protein

Bezeichner auf Proteinebene für UFD1L

ubiquitin fusion degradation protein 1 homolog , ubiquitin fusion degradation 1-like protein , ubiquitin fusion degradation 1-like , ubiquitin fusion degradation 1 like (yeast) , UB fusion protein 1 , fc55f04

GENE ID SPEZIES
374186 Gallus gallus
608300 Canis lupus familiaris
100153062 Sus scrofa
399034 Xenopus laevis
448516 Xenopus (Silurana) tropicalis
458650 Pan troglodytes
711716 Macaca mulatta
6219427 Entamoeba histolytica HM-1:IMSS
100165679 Acyrthosiphon pisum
100166745 Acyrthosiphon pisum
100409073 Callithrix jacchus
100451821 Pongo abelii
100582577 Nomascus leucogenys
100635687 Amphimedon queenslandica
100648660 Bombus terrestris
3565860 Caenorhabditis elegans
22230 Mus musculus
7353 Homo sapiens
84478 Rattus norvegicus
507124 Bos taurus
436724 Danio rerio
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