U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 Proteine (U2AF1L4)

RNA-binding protein that function as a pre-mRNA splicing factor.

alle Proteine anzeigen Gen GeneID UniProt
Human U2AF1L4 U2AF1L4 199746 Q8WU68
Maus U2AF1L4 U2AF1L4 233073 Q8BGJ9
Ratte U2AF1L4 U2AF1L4 361542 Q7TP17
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Weitere Proteine zu U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Interaktionspartnern

Human U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Interaktionspartner

  1. U2AF1L4 (zeige TMEM149 Proteine) gene expression is regulated by cytokines in activated T cells.

  2. a 269 bp region located between the PSENEN (zeige PSENEN Proteine) and U2AF1L4 (zeige TMEM149 Proteine) human genes is a genuine bidirectional promoter regulating a concerted divergent transcription of these genes.

  3. Differential isoform expression and interaction with the P32 (zeige C1QBP Proteine) regulatory protein controls the subcellular localization of the splicing factor (zeige SLU7 Proteine) U2AF26

Mouse (Murine) U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Interaktionspartner

  1. Data suggest light-induced U2af26 alternative splicing to be a buffering mechanism that limits PERIOD1 induction, thus stabilizing the circadian clock against abnormal changes in light:dark conditions.

  2. Differential isoform expression and interaction with the P32 (zeige C1QBP Proteine) regulatory protein (zeige TGFB1 Proteine) controls the subcellular localization of the splicing factor (zeige SLU7 Proteine) U2AF26

U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Protein Überblick

Protein Überblick

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation\; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity).

Genbezeichner und Symbole assoziert mit U2AF1L4

  • U2 small nuclear RNA auxiliary factor 1-like 4 (U2AF1L4)
  • U2 small nuclear RNA auxiliary factor 1-like 4 (LOC100347194)
  • U2 small nuclear RNA auxiliary factor 1-like 4 (U2af1l4)
  • AA407033 Protein
  • AF419339 Protein
  • AI451269 Protein
  • AW553050 Protein
  • TMEM149 Protein
  • U2AF1-RS3 Protein
  • U2AF1L3 Protein
  • U2AF1L3V1 Protein
  • U2AF1RS3 Protein
  • U2af26 Protein

Bezeichner auf Proteinebene für U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4 , transmembrane protein 149 , U2 auxiliary factor 26 , U2 small nuclear RNA auxiliary factor 1-like 3 , U2 small nuclear RNA auxiliary factor 1-like protein 3 , U2 small nuclear RNA auxiliary factor 1-like protein 4 , U2(RNU2) small nuclear RNA auxiliary factor 1-like 3 , U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 , U2AF1-like protein 3 , splicing factor U2AF 26 kDa subunit , auxiliary factor 26 , Cb2-807 , liver regeneration-related protein LRRG157/LRRG158

GENE ID SPEZIES
455961 Pan troglodytes
100347194 Oryctolagus cuniculus
199746 Homo sapiens
476480 Canis lupus familiaris
233073 Mus musculus
361542 Rattus norvegicus
615198 Bos taurus
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