anti-U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Antikörper

U2AF1 belongs to the splicing factor SR family of genes. Zusätzlich bieten wir Ihnen U2AF1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
U2AF1 108121 Q9D883
U2AF1 7307 Q01081
U2AF1 687575  
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Top anti-U2AF1 Antikörper auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-U2AF1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human Stomach 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with U2AF1 antibody (Center S70), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-U2AF1 Antibody (Center S70) (ABIN389304) in Ramos cell line lysates (35 µg/lane).U2AF1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of anti-U2AF1 Antibody (Center Y114) (ABIN389305) in Ramos cell line lysates (35 µg/lane).U2AF1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with NRP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: U2AF35 Antibody [NBP1-19120] - FFPE section of mouse colon carcinoma. Antibody used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert ICC, IF, IP, IHC (p), WB WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 12% SDS PAGE antibody diluted at 1:1000 IP Image Immunoprecipitation of U2AF35 protein from 293T whole cell extracts using 5 μg of U2AF35 antibody, Western blot analysis was performed using U2AF35 antibody, EasyBlot anti-Rabbit IgG  was used as a secondary reagent. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert WB U2AF1 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: U2AF35 Antibody [NBP1-32515] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution. Immunohistochemistry-Paraffin: U2AF35 Antibody [NBP1-32515] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
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U2AF1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine) ,


Human , ,
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Rat (Rattus) ,


Am meisten referenzierte anti-U2AF1 Antikörper

  1. Human Polyclonal U2AF1 Primary Antibody für ICC, IF - ABIN438948 : Wang, Wilson-Berry, Schedl, Hansen: TEG-1 CD2BP2 regulates stem cell proliferation and sex determination in the C. elegans germ line and physically interacts with the UAF-1 U2AF65 splicing factor. in Developmental dynamics : an official publication of the American Association of Anatomists 2012 (PubMed)

  2. Human Polyclonal U2AF1 Primary Antibody für ICC, IF - ABIN4363831 : Stadler, Fagerberg, Sivertsson, Oksvold, Zwahlen, Hallström, Lundberg, Uhlén: RNA- and antibody-based profiling of the human proteome with focus on chromosome 19. in Journal of proteome research 2014 (PubMed)

Weitere Antikörper gegen U2AF1 Interaktionspartner

Mouse (Murine) U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Interaktionspartner

  1. The U2AF35(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 (zeige ATG7 Antikörper) pre-mRNA, decreasing levels of ATG7 (zeige ATG7 Antikörper) protein and defective autophagy, ultimately leading to transformation.

  2. data support the impact of genes from the Abcg1 (zeige ABCG1 Antikörper)-U2af1 region as modifiers of Tc1 (zeige C8orf4 Antikörper)-dependent memory and locomotor phenotypes in Tc1 (zeige C8orf4 Antikörper) mouse model of Down syndrome.

  3. findings support the hypothesis that mutant U2AF1 alters downstream gene isoform expression, thereby contributing to abnormal hematopoiesis in patients with MDS (zeige MECOM Antikörper)

  4. this study establishes definitely the contribution of the Abcg1 (zeige ABCG1 Antikörper)-U2af1 orthologous region to the DS etiology and suggests new modulatory pathways for learning and memory.

Human U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Interaktionspartner

  1. infer that U2AF1 S34 mutations characterize a distinct subgroup of myelodysplastic syndrome

  2. The U2AF35(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 (zeige ATG7 Antikörper) pre-mRNA, decreasing levels of ATG7 (zeige ATG7 Antikörper) protein and defective autophagy, ultimately leading to transformation.

  3. Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons controlled by SRF3.

  4. Our results provide mechanistic explanations of the magnitude of splicing changes observed in U2AF1-mutant cells and why tumors harboring U2AF1 mutations always retain an expressed copy of the wild-type allele

  5. Mutations in ASXL1 (zeige ASXL1 Antikörper), U2AF1, and SF3B1 (zeige SF3B2 Antikörper) are common in Chinese patients with myelodysplastic syndromes.

  6. in primary myelofibrosis, anemia was significantly associated with U2AF1 mutation; study confirms previous observation regarding the association of mutant U2AF1 with anemia supporting its role in hematopoiesis and in the pathogenesis of PMF-associated anemia

  7. In multivariate analysis, U2AF1 and TP53 (zeige TP53 Antikörper) mutations retained independent prognostic significance across 93 cases of acute myeloid leukemia (zeige BCL11A Antikörper)

  8. The mutational status of the SRSF2 (zeige SRSF2 Antikörper), U2AF1 and ZRSR2 (zeige ZRSR2 Antikörper) did not affect the response rate or survival in MDS (zeige PAFAH1B1 Antikörper) patients who had received first-line decitabine treatment.

  9. A mutant U2AF1 (S34F) found in a variety of cancer types results in delayed splicing and disruption of kinetic competition during transcription.

  10. The S34F mutation alters U2AF1 function in the context of specific RNA sequences, leading to aberrant alternative splicing of target genes, some of which may be relevant for myelodysplastic syndromes pathogenesis.

U2AF1 Antigen-Profil

Protein Überblick

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit U2AF1

  • U2 small nuclear RNA auxiliary factor 1 (U2AF1) Antikörper
  • CCHC-type zinc finger-containing protein (u2af1) Antikörper
  • U2 small nuclear RNA auxiliary factor 1 (u2af1) Antikörper
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 (U2af1) Antikörper
  • U2 small nuclear RNA auxiliary factor 1 (U2af1) Antikörper
  • U2(RNU2) small nuclear RNA auxiliary factor 1 (u2af1) Antikörper
  • 35kDa Antikörper
  • 2010107D16Rik Antikörper
  • CHUNP6860 Antikörper
  • DDBDRAFT_0218665 Antikörper
  • DDBDRAFT_0233354 Antikörper
  • DDB_0218665 Antikörper
  • DDB_0233354 Antikörper
  • FP793 Antikörper
  • RN Antikörper
  • RNU2AF1 Antikörper
  • U2AF35 Antikörper
  • U2AFBP Antikörper
  • zgc:111896 Antikörper

Bezeichner auf Proteinebene für U2AF1

U2 small nuclear RNA auxiliary factor 1 , RNA recognition motif-containing protein RRM , RNA-binding region RNP-1 domain-containing protein , U2 snRNP auxiliary factor small subunit , U2(RNU2) small nuclear RNA auxiliary factor 1 , U2 auxiliary factor 35 kDa subunit , U2 small nuclear ribonucleoprotein auxiliary factor (U2AF),35 kDa , splicing factor U2AF 35 kDa subunit , U2 small nuclear RNA auxillary factor 1 , U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit , U2(RNU2) small nuclear RNA auxiliary factor binding protein , splicing factor U2AF 35kDa subunit , U2snRNP auxiliary factor small subunit , uncharacterized protein LOC687575 , U2(RNU2) small nuclear RNA auxillary factor 1

GENE ID SPEZIES
478422 Canis lupus familiaris
8624909 Dictyostelium discoideum AX4
733934 Xenopus (Silurana) tropicalis
737227 Pan troglodytes
108121 Mus musculus
7307 Homo sapiens
734926 Xenopus laevis
395370 Gallus gallus
512680 Bos taurus
687575 Rattus norvegicus
192328 Danio rerio
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