anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) Antikörper

The protein encoded by TNK1 belongs to the tyrosine protein kinase family. Zusätzlich bieten wir Ihnen TNK1 Kits (4) und TNK1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNK1 83813 Q99ML2
TNK1 8711 Q13470
TNK1 303247  
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Top anti-TNK1 Antikörper auf antikoerper-online.de

Showing 10 out of 128 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB <b>Host: </b>Rabbit<br><b>Target Name: </b>TNK1<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>RPMI-8226 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-TNK1 pab (ABIN392113) in Hela cell line lysate. Dilution of anti-TNK1 was 1:100. dilution of secondary antibody (goat anti-rabbit-HRP) was 1:7000. Data and protocol courtesy of Dr. Richard Lu, Partners HealthCare System at Harvard University. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of TNK1 Antibody (ABIN652385) in T47D cell line lysates (35 µg/lane). TNK1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 10 bis 11 Tage
$428.57
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Phospho-TNK1(Tyr277) Polyclonal Antibody, Unconjugated (ABIN746513) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Human Maus Unkonjugiert IHC (p), WB TNK1 Antibody  western blot analysis in mouse brain cell line lysates (15ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow).(1:500) TNK1 Monoclonal( Ascites)  immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the TNK1 Monoclonal( Ascites) for immunohistochemistry.  Clinical relevance has not been evaluated. 0.1 mL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Maus Unkonjugiert WB TNK1 Antibody  western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert EIA, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: Kos1/Tnk1 Antibody [ABIN152577] - T47D cells expressing GFP/GFP-Kos were lysed in RIPA lysis buffer. 500ug protein from clarified cell lysates was immunoprecipitated with an anti-GFP antibody. The washed immunoprecipitates were electrophoresed on 8% SDS-PAGE gel and the proteins were transferred to nitrocellulose membrane. Panel A indicates GFP and GFP-Kos when probed with anti-GFP antibody. The blot was stripped thereafter, and GFP-Kos was detected with Kos1/Tnk1 antibody (ABIN152577) at a dilution of 1:1000 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$317.63
Details

TNK1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TNK1 Antikörper

  1. Human Monoclonal TNK1 Primary Antibody für ELISA, WB - ABIN1724711 : Hoare, Hoare, Smith, Kalmaz, Small, Stratford May: Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling. in Oncogene 2003 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal TNK1 Primary Antibody für IHC (p), WB - ABIN392113 : Henderson, Gonzales, Arora, Choudhary, Trent, Von Hoff, Mousses, Azorsa: High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells. in Molecular cancer research : MCR 2011 (PubMed)

Weitere Antikörper gegen TNK1 Interaktionspartner

Mouse (Murine) Tyrosine Kinase, Non-Receptor, 1 (TNK1) Interaktionspartner

  1. The activated TNK1 potentiates JAK (zeige JAK3 Antikörper)-STAT (zeige STAT1 Antikörper) signaling through dual phosphorylation of STAT1 (zeige STAT1 Antikörper) at tyrosine 701 and serine 727 amino acid positions.

  2. data support a negative regulatory role for Kos1 in regulating the Ras-Raf1 (zeige RAF1 Antikörper)-MAPK (zeige MAPK1 Antikörper) growth pathway by a mechanism that requires its autotyrosine kinase activity

  3. Tnk1/Kos1 is a tumor suppressor that functions to down-regulate Ras activity

  4. cellular stress reverses the repression of Tnk1/Kos1 and induces its expression through increased high affinity interactions between nuclear proteins Sp1 (zeige SP1 Antikörper), Sp3 (zeige SP3 Antikörper), AP2 (zeige TFAP2A Antikörper) and MED1 (zeige MBD4 Antikörper) for the m-Tnk1 promoter

Human Tyrosine Kinase, Non-Receptor, 1 (TNK1) Interaktionspartner

  1. The activated TNK1 potentiates JAK (zeige JAK3 Antikörper)-STAT (zeige STAT1 Antikörper) signaling through dual phosphorylation of STAT1 (zeige STAT1 Antikörper) at tyrosine 701 and serine 727 amino acid positions.

  2. The application of functional genomics by using high-throughput-RNAi screens has allowed us to identify TNK1 as a growth-associated kinase in pancreatic cancer cells.

  3. Activated Tnk1 kinase is associated with Hodgkin's lymphoma.

  4. TNK1 therefore acts as a novel molecular switch that can determine the properties of TNFalpha (zeige TNF Antikörper) signaling and therefore cell death.

TNK1 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TNK1

  • tyrosine kinase, non-receptor, 1 (TNK1) Antikörper
  • tyrosine kinase, non-receptor, 1 (Tnk1) Antikörper
  • Ack-like Antikörper
  • Kos1 Antikörper
  • Tnk1a Antikörper
  • Tnk1b Antikörper

Bezeichner auf Proteinebene für TNK1

kinase of embryonic stem cells , non-receptor tyrosine kinase , non-receptor tyrosine-protein kinase TNK1 , CD38 negative kinase 1

GENE ID SPEZIES
100061776 Equus caballus
83813 Mus musculus
8711 Homo sapiens
303247 Rattus norvegicus
510356 Bos taurus
489470 Canis lupus familiaris
100735628 Cavia porcellus
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