Twisted Gastrulation Homolog 1 (Drosophila) Proteine (TWSG1)

May be involved in dorsoventral axis formation. Zusätzlich bieten wir Ihnen TWSG1 Antikörper (42) und TWSG1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TWSG1 65960 Q9EP52
TWSG1 57045 Q9GZX9
Ratte TWSG1 TWSG1 363294  
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Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
429,52 €
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HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
238,10 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
407,41 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 50 μg Anmelden zum Anzeigen 8 bis 11 Tage
218,90 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 10 bis 13 Tage
322,10 €
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HOST_HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
438,90 €
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.362,38 €
Details

TWSG1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , , , ,
,

Am meisten referenzierte TWSG1 Proteine

  1. Human TWSG1 Protein expressed in Wheat germ - ABIN1324209 : Tanno, Bhanu, Oneal, Goh, Staker, Lee, Moroney, Reed, Luban, Wang, Eling, Childs, Ganz, Leitman, Fucharoen, Miller: High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. in Nature medicine 2007 (PubMed)

Weitere Proteine zu Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartnern

Zebrafish Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Twisted (zeige POMT2 Proteine) gastrulation enhances BMP signaling through chordin (zeige CHRD Proteine) dependent and independent mechanisms

Mouse (Murine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Our results show that BMP binding is required for TWSG1-mediated inhibition of osteoclast formation and function, and validate the critical functional regions within the TWSG1 protein for these interactions

  2. The goal of this study was to examine whether mice carrying a mutation in a gene encoding Twsg1, which is associated with a low penetrance of holoprosencephaly, are sensitized to retinoic acid teratogenesis.

  3. BMP-binding protein twisted (zeige POMT2 Proteine) gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

  4. Data show that Bmp4 (zeige BMP4 Proteine), Bmp7 (zeige BMP7 Proteine), Gremlin (zeige GREM1 Proteine) and Twisted (zeige POMT2 Proteine) gastrulation (Twsg1) are all expressed in the thymus and expression was clearly different for each gene investigated.

  5. suggesting that Twsg1 expression in B cells serves to interpret BMP signals on a per-cell basis

  6. These results demonstrate that phenotypic variability in Twsg1-/- mice is associated with differential expression of certain developmentally regulated genes, and that craniofacial defects can be partially rescued by reduced p53 (zeige TP53 Proteine) levels.

  7. TWSG1 overexpression inhibits RANKL (zeige TNFSF11 Proteine)-induced osteoclast differentiation

  8. TWSG1 appears to be the main regulator of BMP present in CP.

  9. Cv2 (zeige BMPER Proteine) enhances pro-BMP activity of Tsg.

  10. The developmentally regulated expression of Twisted (zeige POMT2 Proteine) gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.

Human Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Data suggest CHRD (chordin) cleavage by tolloid-like metalloproteinases is insufficient to regulate BMP(bone morphogenetic protein)/BMPR signaling; CHRD fragments and TSG (twisted gastrulation protein) contribute to inhibition of BMP/BMPR signaling.

  2. these results suggest that BMPER and Tsg maintain a fine-tuned equilibrium that controls BMP pathway activity and is necessary for vascular cell homeostasis.

  3. mutations in the twisted gastrulation homolog 1 gene are neither a common direct cause nor a frequent modifying factor for human holoprosencephaly pathologies

  4. Tsg functions as an agonist synergizing with TGF-beta (zeige TGFB1 Proteine) to inhibit T-cell activation.

  5. interferes with BMP-mediated hepcidin (zeige HAMP Proteine) expression and may act with GDF15 (zeige GDF15 Proteine) to dysregulate iron homeostasis in thalassemia syndromes.

Cow (Bovine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation

TWSG1 Protein Überblick

Protein Überblick

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).

Genbezeichner und Symbole assoziert mit TWSG1

  • twisted gastrulation homolog 1a (Drosophila) (twsg1a)
  • twisted gastrulation homolog 1 (Drosophila) (TWSG1)
  • twisted gastrulation homolog 1 (Drosophila) (Twsg1)
  • 1810013J15Rik Protein
  • 9030422N06Rik Protein
  • AW552143 Protein
  • D17Ertd403e Protein
  • DKFZp469J051 Protein
  • fi23f01 Protein
  • Tsg Protein
  • tsga Protein
  • Twg Protein
  • TWSG1 Protein
  • wu:fi23f01 Protein

Bezeichner auf Proteinebene für TWSG1

twisted gastrulation 1 , twisted gastrulation a , twisted gastrulation protein homolog 1-A , twisted gastrulation homolog 1 (Drosophila) , twisted gastrulation homolog 1 , Twisted gastrulation protein homolog 1 , twisted gastrulation protein homolog 1

GENE ID SPEZIES
84037 Danio rerio
455294 Pan troglodytes
705804 Macaca mulatta
100172557 Pongo abelii
65960 Mus musculus
57045 Homo sapiens
374024 Gallus gallus
490546 Canis lupus familiaris
537290 Bos taurus
363294 Rattus norvegicus
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