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Navigieren Sie durch unsere anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) Antikörper

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anti-Tumor Protein P53 Binding Protein 1 Antikörper (TP53BP1)
Auf antikoerper-online.de finden Sie aktuell 172 Tumor Protein P53 Binding Protein 1 (TP53BP1) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Tumor Protein P53 Binding Protein 1 Kits (9) und Tumor Protein P53 Binding Protein 1 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 185 Tumor Protein P53 Binding Protein 1 Produkte verfügbar.
Synonyme:
53BP1, m53BP1, MGC160112, p202, Tp53bp1, Trp53bp1
Alle Antikörper anzeigen Gen GeneID UniProt
TP53BP1 27223 P70399
TP53BP1 7158 Q12888
TP53BP1 296099  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Tumor Protein P53 Binding Protein 1 Antikörper

  1. Human Polyclonal TP53BP1 Primary Antibody für WB,ChIP - ABIN251421 : Silverman, Takai, Buonomo, Eisenhaber, de Lange: Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. in Genes & development 2004 (PubMed)
    Zeige alle 8 Referenzen für ABIN251421

  2. Human Polyclonal TP53BP1 Primary Antibody für WB,ICC - ABIN407419 : Murga, Jaco, Fan, Soria, Martinez-Pastor, Cuadrado, Yang, Blasco, Skoultchi, Fernandez-Capetillo: Global chromatin compaction limits the strength of the DNA damage response. in The Journal of cell biology 2007 (PubMed)
    Zeige alle 4 Referenzen für ABIN407419

  3. Human Monoclonal TP53BP1 Primary Antibody für WB,BI - ABIN968860 : Iwabuchi, Bartel, Li, Marraccino, Fields: Two cellular proteins that bind to wild-type but not mutant p53. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Zeige alle 3 Referenzen für ABIN968860

  4. Human Polyclonal TP53BP1 Primary Antibody für WB,ChIP - ABIN251419 : Riballo, Kühne, Rief, Doherty, Smith, Recio, Reis, Dahm, Fricke, Krempler, Parker, Jackson, Gennery, Jeggo, Löbrich: A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. in Molecular cell 2004 (PubMed)
    Zeige alle 3 Referenzen für ABIN251419

  5. Human Monoclonal TP53BP1 Primary Antibody für ELISA,WB - ABIN1724821 : Nakada, Yonamine, Matsuo: RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1. in Cancer research 2012 (PubMed)
    Zeige alle 2 Referenzen für ABIN1724821

  6. Human Polyclonal TP53BP1 Primary Antibody für IHC (p),IF (p) - ABIN682993 : Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis. in The Journal of biological chemistry 2015 (PubMed)

  7. Human Polyclonal TP53BP1 Primary Antibody für WB,FACS - ABIN151311 : Kang, Lee, Hoan, Sohn, Chang, You: Protein phosphatase 5 regulates the function of 53BP1 after neocarzinostatin-induced DNA damage. in The Journal of biological chemistry 2009 (PubMed)

Weitere Antikörper gegen Tumor Protein P53 Binding Protein 1 Interaktionspartner

Mouse (Murine) Tumor Protein P53 Binding Protein 1 (TP53BP1) Interaktionspartner

  1. Study showed that mammalian cells use microtubules in the cytoplasm to promote the mobility of sites of DNA damage in the nucleus; molecular details of this process remain to be determined, the main players, including the MOB (zeige SGMS1 Antikörper) domain of 53BP1, the linker of the nucleoskeleton, and cytoskeleton complex, kinesins, and microtubules are now known, allowing further study.

  2. These experiments define a novel requirement for 53BP1 in the fusions of DNA-PKcs (zeige PRKDC Antikörper)-deficient telomeres throughout the cell cycle.

  3. Study concludes that only the 53BP1 status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (zeige LMNA Antikörper) deficiency, which was not observed for heterochromatin-related proteins HP1beta (zeige CBX1 Antikörper) and BMI1 (zeige BMI1 Antikörper).

  4. Binding of 53BP1 to methyl K810 occurs on E2 promoter binding factor (zeige E2F1 Antikörper) target genes and allows pRb (zeige PGR Antikörper) activity to be effectively integrated with the DNA damage response.

  5. study uncovers novel ATM (zeige ATM Antikörper)-independent functions for 53BP1 in the suppression of oncogenic translocations and in radioprotection

  6. Study concludes that 53BP1 promotes productive class switch recombination and suppresses mutagenic DNA repair through distinct phosphodependent interactions with RIF1 (zeige RIF1 Antikörper) and PTIP (zeige PAXIP1 Antikörper).

  7. Thus, RIF1 and 53BP1 cooperate to block DSB resection to promote NHEJ in G1, which is antagonized by BRCA1 in S phase to ensure a switch of DSB repair mode to homologous recombination

  8. loss of 53BP1 alters the translocatome by increasing rearrangements to intergenic regions.

  9. A mutant lacking the oligomerization domain (53BP1(oligo)) was only modestly impaired in promoting NHEJ of dysfunctional telomeres and showed no defect with regard to the repression of CtIP (zeige RBBP8 Antikörper).

  10. data establish Rif1 (zeige RIF1 Antikörper) as an important contributor to the control of double-strand break repair by 53BP1

Human Tumor Protein P53 Binding Protein 1 (TP53BP1) Interaktionspartner

  1. After nanogold treatment, an inverse correlation between the formation of 53BP1 foci and micronuclei generation was observed. The robust 53BP1 recruitment resulted in reduced micronuclei production

  2. Studies performed genotyping analyses of eight functional CDKN1A p21 (zeige CDKN1A Antikörper), oncoprotein p53 (zeige TP53 Antikörper), TP53BP1 protein and tumor protein p73 (zeige TP73 Antikörper) single nucleotide polymorphisms (SNPs) in 330 gastric cardia adenocarcinoma (GCA (zeige NPR1 Antikörper)) cases and 608 controls in a Chinese population.

  3. we generated two HEP (zeige EPHB6 Antikörper)-2 cell lines with a stable knockdown of MDC1 (zeige MDC1 Antikörper) or 53BP1 with short hairpin RNA (shRNA), respectively, and investigated the effect of MDC1 (zeige MDC1 Antikörper) and 53BP1 on cell radiosensitivity

  4. 53BP1 binds to lamins A/C via its Tudor domain, and this is abrogated by DNA damage. Lamins A/C regulate 53BP1 levels and consequently lamin A/C (zeige LMNA Antikörper)-null HDF (zeige Vcan Antikörper) display a 53BP1 null-like phenotype.

  5. CK2 (zeige CSNK2A1 Antikörper)/WIP1 (zeige PPM1D Antikörper)-mediated modulation of LSD1 (zeige KDM1A Antikörper) phosphorylation facilitates RNF168 (zeige RNF168 Antikörper)-dependent ubiquitination and recruitment of 53BP1 to the DNA damage sites.

  6. 53BP1 functioned as a tumor suppressor gene by its novel negative control of Epithelial-mesenchymal transition through regulating the expression of miR (zeige MLXIP Antikörper)-200b/429 and their target gene ZEB1 (zeige ZEB1 Antikörper).

  7. ATMIN (zeige ATMIN Antikörper) is required for the ATM (zeige ATM Antikörper)-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.

  8. Depletion of RNF8 (zeige RNF8 Antikörper) or RNF168 (zeige RNF168 Antikörper) blocks the degradation of diffusely localized nuclear 53BP1.

  9. Depletion of both 53BP1 and BRCA1 increases repair needing microhomology usage and augments loss of DNA sequence, suggesting that MMEJ is a highly regulated DSB repair process

  10. UbcH7 (zeige UBE2L3 Antikörper) has a role in regulating 53BP1 stability and DSB repair

Tumor Protein P53 Binding Protein 1 (TP53BP1) Antigen-Profil

Beschreibung des Gens

May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Binds to sites of DNA damage. Plays a role in the response to DNA damage (By similarity).

Alternative names and synonyms associated with Tumor Protein P53 Binding Protein 1 (TP53BP1)

  • tumor protein p53 binding protein 1 (TP53BP1) Antikörper
  • tumor protein p53 binding protein 1 (tp53bp1) Antikörper
  • tumor protein p53 binding protein 1 (predicted), 5 prime (TP53BP1) Antikörper
  • transformation related protein 53 binding protein 1 (Trp53bp1) Antikörper
  • tumor protein p53 binding protein 1 (Tp53bp1) Antikörper
  • 53BP1 Antikörper
  • m53BP1 Antikörper
  • MGC160112 Antikörper
  • p202 Antikörper
  • Tp53bp1 Antikörper
  • Trp53bp1 Antikörper

Bezeichner auf Proteinebene für TP53BP1

tumor protein p53 binding protein 1 , tumor protein p53 binding protein, 1 , tumor suppressor p53-binding protein 1-like , tumor protein p53 binding protein 1 (predicted), 5 prime , tumor protein p53 binding protein 1 (predicted), 3 prime , murine p53-binding protein , p53-binding protein 1 , p53BP1 , transformation related protein 53 binding-protein 1 , tumor suppressor p53-binding protein 1 , tumor protein 53-binding protein, 1 , tumor protein p53-binding protein, 1 , transformation related protein 53 binding protein 1

GENE ID SPEZIES
415589 Gallus gallus
467668 Pan troglodytes
478274 Canis lupus familiaris
509111 Bos taurus
100137429 Papio anubis
100468474 Ailuropoda melanoleuca
100490124 Xenopus (Silurana) tropicalis
100550605 Meleagris gallopavo
100607698 Nomascus leucogenys
100328680 Oryctolagus cuniculus
27223 Mus musculus
7158 Homo sapiens
296099 Rattus norvegicus
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