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The protein encoded by TNFRSF8 is a member of the TNF-receptor superfamily. Zusätzlich bieten wir Ihnen TNFRSF8 Antikörper (696) und TNFRSF8 Kits (34) und viele weitere Produktgruppen zu diesem Protein an.
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This study demonstrated the amelioration of MOG35-55 peptide-induced active EAE in CD30 KO mice. CD30 was expressed limitedly on CD4 (zeige CD4 Proteine) T cells at the induction phase of experimental autoimmune encephalomyelitis.
Data indicate that CD30L (zeige TNFSF8 Proteine)/CD30 axis plays a modulatory role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE).
role in the maintenance and activation of IL-17A (zeige IL17A Proteine)-producing gammadelta T cells
These results suggest that CD30 signaling plays an important role in the activation of IL-17A (zeige IL17A Proteine)-producing Vgamma1(-) Vgamma4(-) gammadelta T cells bearing Vgamma6 at an early stage of BCG (zeige SLC11A1 Proteine) infection.
Interference of the CD30-CD30L (zeige TNFSF8 Proteine) pathway reduces atherosclerosis development.
CD30L (zeige TNFSF8 Proteine)/CD30 pathway acts as an accelerator of enteritis in a murine disease model
role of CD30L (zeige TNFSF8 Proteine)/CD30 interactions in allergic rhinitis; results suggest that CD30L (zeige TNFSF8 Proteine) plays an important role in allergic rhinitis
Abrogation of CD30 and OX40 (zeige TNFRSF4 Proteine) signals prevents autoimmune disease in FoxP3 (zeige FOXP3 Proteine)-deficient mice.
Studies demonstrate that CD30L (zeige TNFSF8 Proteine)/CD30 signaling executed by the T-T cell interaction plays a critical role in Th17 cell differentiation.
CD30 can signal in a completely TCR-independent fashion to induce IL-13 (zeige IL13 Proteine) production by effector T cells.
Expression of CD30 in patients with both DLBCL and other aggressive B-cell lymphomas and the absence of MYC (zeige MYC Proteine) oncogene (zeige RAB1A Proteine)-driven proliferation in the majority of these tumors suggests that brentuximab may be a particularly effective form of targeted therapy in the subset of patients with high CD30 expression.
Prevalence of the CD30 (Ki-1) antigen in human solid tumors was summarized.
CD30 expression was detected in up to 25% of cases of diffuse large B-cell lymphoma and was more frequent in tumors without MYC (zeige MYC Proteine) rearrangement. CD30 expression was not associated with overall survival in R-EPOCH-treated de novo DLBCL patients.
CD30 facilitates phosphorylation of heat shock factor 1, activates heat shock promoter element, and induces heat shock protein (HSP) 90 (zeige HSP90AA1 Proteine).
this study shows that polyclonal and allogeneic stimulation induced higher levels of CD30 transcripts in end-stage renal disease patients compared to control patients
CD30 expression was not associated with prognosis in our cohort of de novoDLBCL, including in patients who received aggressive chemotherapy. CD30 expression and MYC (zeige MYC Proteine) rearrangement were mutually exclusive in de novoDLBCL.
Case Report: CD30 positive lymphomatoid papulosis arising in association with cutaneous amyloidosis in a patient with multiple myeloma.
The heterogeneity of CD30 expression in refractory or relapsed peripheral T-cell lymphoma patients indicates the likelihood for better response for patients with strong CD30 expression by tumor cells.
CD30 may be useful as a prognostic marker in rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP (zeige DDIT3 Proteine)) treated DLBCLs, indicating favorable outcomes in a Chinese population.
this review is focused on the role of CD30 receptor and p53 as novel targets for therapy in ALK+ ALCL, and also provides an update on their potential involvement in ALK+ ALCL pathogenesis
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
, Ki-1 antigen
, cytokine receptor CD30
, lymphocyte activation antigen CD30
, tumor necrosis factor receptor superfamily member 8
, Tumor necrosis factor superfamily member 8
, tumor necrosis factor superfamily, member CD30
, tumor necrosis factor receptor superfamily, member 8
, tumor necrosis factor ligand superfamily member 8
, tumor necrosis factor receptor superfamily member 8-like