Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine (TNFRSF11B)

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Receptor Superfamily, Member 11b Antikörper (173) und Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (80) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 18383 O08712
TNFRSF11B 25341 O08727
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Showing 10 out of 41 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293 Maus Unkonjugiert 25 μg Anmelden zum Anzeigen 6 bis 8 Tage
129,41 €
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HOST_Human Cells Rhesusaffen Fc Tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293 Cells Human His tag Human Osteoprotegerin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
234,29 €
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HOST_Human Cells Maus Fc Tag SDS-PAGE 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
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HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Anmelden zum Anzeigen 7 bis 8 Tage
841,60 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
119,05 €
Details

TNFRSF11B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , , , , , ,
, , ,
Mouse (Murine) , ,
,
Rat (Rattus)

Am meisten referenzierte Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine

  1. Mouse (Murine) TNFRSF11B Protein expressed in HEK-293 - ABIN2666866 : Boyce, Xing: Biology of RANK, RANKL, and osteoprotegerin. in Arthritis research & therapy 2007 (PubMed)
    Zeige alle 7 Referenzen für 2666866

  2. Human TNFRSF11B Protein expressed in HEK-293 Cells - ABIN2181847 : Tsuda, Goto, Mochizuki, Yano, Kobayashi, Morinaga, Higashio: Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. in Biochemical and biophysical research communications 1997 (PubMed)
    Zeige alle 4 Referenzen für 2181847

  3. Human TNFRSF11B Protein expressed in Human Cells - ABIN2002484 : Simonet, Lacey, Dunstan, Kelley, Chang, Lüthy, Nguyen, Wooden, Bennett, Boone, Shimamoto, DeRose, Elliott, Colombero, Tan, Trail, Sullivan, Davy, Bucay, Renshaw-Gegg, Hughes, Hill, Pattison, Campbell et al.: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. ... in Cell 1997 (PubMed)
    Zeige alle 4 Referenzen für 2002484

  4. Rhesus Monkey TNFRSF11B Protein expressed in Human Cells - ABIN2009907 : Yasuda, Shima, Nakagawa, Mochizuki, Yano, Fujise, Sato, Goto, Yamaguchi, Kuriyama, Kanno, Murakami, Tsuda, Morinaga, Higashio: Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. in Endocrinology 1998 (PubMed)
    Zeige alle 4 Referenzen für 2009907

Weitere Proteine zu Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartnern

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. Physical activity does not increase circulating osteoprotegerin level.

  2. OPG may be a potential driver of lung cancer cells and therefore might have potential in therapy and diagnostics.

  3. our findings suggest OPG is a downstream effector of IL1B (zeige IL1B Proteine)-mediated invasion in breast cancer cells.

  4. measurement of serum osteoprotegerin concentration might be useful as a surrogate marker for determining bone loss in patients with chronic kidney disease, especially for women, although not so much for men.

  5. In patients with tightly controlled rheumatoid arthritis, serum OPG was inversely associated with progression of joint destruction.

  6. estrogen may post-transcriptionally regulate OPG expression through suppression of miR (zeige MLXIP Proteine)-145 expression.

  7. TNFRSF11B mutation is associated with Juvenile Paget's disease.

  8. Review: OPG, RANKL (zeige TNFSF11 Proteine) and TRAIL are involved in vascular calcification.

  9. we report the involvement of OPG in cellular and molecular changes in MVP (zeige MVP Proteine) isolated cells. In addition, we detected elevated circulating OPG levels in MVP (zeige MVP Proteine) patients when compared to controls, which supports the hypothesis that OPG is involved in MVP (zeige MVP Proteine) development and progression.

  10. Our results suggest that the polymorphism of the RANKL (zeige TNFSF11 Proteine), RANK, and OPG genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. RANK/RANKL (zeige TNFSF11 Proteine) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.

  2. endocortical resorption is driven by reduced OPG (zeige TNFSF11 Proteine) rather than elevated RANKL (zeige TNFSF11 Proteine) expression

  3. Diabetes significantly increased OPG (zeige TNFSF11 Proteine) and the OPG (zeige TNFSF11 Proteine)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Proteine) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Proteine)/TRAIL ratio.

  4. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (zeige TNFSF11 Proteine) interaction and osteoclastogenesis.

  5. OPG (zeige TNFSF11 Proteine) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  6. These data suggested that OPG (zeige TNFSF11 Proteine) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  7. Data show that p38alpha (zeige MAPK14 Proteine) mitogen-activated protein kinase (zeige MAPK1 Proteine) (MAPK (zeige MAPK1 Proteine)) in paired related homeobox 1 (zeige PRRX1 Proteine) protein (Prx1 (zeige PRDX1 Proteine)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  8. OPG (zeige TNFSF11 Proteine) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  9. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  10. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. The OPG (zeige TNFSF11 Proteine) expression levels decreased while those of RANKL (zeige TNFSF11 Proteine) and RUNX2 (zeige RUNX2 Proteine) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (zeige TNFSF11 Proteine) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Protein Überblick

Protein Überblick

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).

Genbezeichner und Symbole assoziert mit TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • basic transcription factor 3 pseudogene 11 (BTF3P11)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • osteoprotegerin (LOC100037695)
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b)
  • BTF3L1 Protein
  • HUMBTFB Protein
  • ocif Protein
  • opg Protein
  • TNFRSF11B Protein
  • tr1 Protein

Bezeichner auf Proteinebene für TNFRSF11B

osteoclastogenesis inhibitory factor , osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like

GENE ID SPEZIES
4982 Homo sapiens
690 Homo sapiens
18383 Mus musculus
25341 Rattus norvegicus
464351 Pan troglodytes
523822 Bos taurus
100037695 Ovis aries
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100348133 Oryctolagus cuniculus
100049688 Sus scrofa
100860896 Capra hircus
100065885 Equus caballus
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