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Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine (TNFRSF11B)

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Receptor Superfamily, Member 11b Antikörper (117) und Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (70) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 25341 O08727
Maus TNFRSF11B TNFRSF11B 18383 O08712
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Showing 10 out of 27 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_HEK-293 Cells Human Fc Tag Human Osteoprotegerin, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
234,29 €
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HOST_Hi-5 Human His tag 30 μg Anmelden zum Anzeigen 11 bis 15 Tage
387,62 €
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HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
188,57 €
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HOST_HEK-293 Cells Human His tag   20 μg Anmelden zum Anzeigen 6 bis 8 Tage
226,98 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
273,54 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 10 bis 13 Tage
403,06 €
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HOST_HEK-293 Human His tag   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
407,27 €
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HOST_HEK-293 Human Fc Tag   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
407,27 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.900,16 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.903,65 €
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TNFRSF11B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
,
Rat (Rattus)

Am meisten referenzierte Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine

  1. Human TNFRSF11B Protein expressed in HEK-293 Cells - ABIN2181849 : Tsuda, Goto, Mochizuki, Yano, Kobayashi, Morinaga, Higashio: Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. in Biochemical and biophysical research communications 1997 (PubMed)
    Zeige alle 4 Referenzen für ABIN2181849

  2. Human TNFRSF11B Protein expressed in Hi-5 - ABIN666742 : Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Zeige alle 3 Referenzen für ABIN666742

Weitere Proteine zu Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartnern

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. measurement of serum osteoprotegerin concentration might be useful as a surrogate marker for determining bone loss in patients with chronic kidney disease, especially for women, although not so much for men.

  2. In patients with tightly controlled rheumatoid arthritis, serum OPG was inversely associated with progression of joint destruction.

  3. estrogen may post-transcriptionally regulate OPG expression through suppression of miR (zeige MLXIP Proteine)-145 expression.

  4. TNFRSF11B mutation is associated with Juvenile Paget's disease.

  5. Review: OPG, RANKL (zeige TNFSF11 Proteine) and TRAIL are involved in vascular calcification.

  6. we report the involvement of OPG in cellular and molecular changes in MVP (zeige MVP Proteine) isolated cells. In addition, we detected elevated circulating OPG levels in MVP (zeige MVP Proteine) patients when compared to controls, which supports the hypothesis that OPG is involved in MVP (zeige MVP Proteine) development and progression.

  7. Our results suggest that the polymorphism of the RANKL (zeige TNFSF11 Proteine), RANK, and OPG genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

  8. The study results showed that people carrying the CC genotype of rs2073618 were more likely to have peri (zeige PLIN1 Proteine)-implantitis than GG genotype carriers (OR=2.18). Patients with the C allele had 1.47 times the risk of suffering from peri (zeige PLIN1 Proteine)-implantitis (OR=1.47), but not rs2073617 polymorphism. The G-C haplotype frequency of rs2073618-rs2073617 in OPG was significantly correlated to the increased susceptibility of peri (zeige PLIN1 Proteine)-implantitis.

  9. OPG rs2073618, RANK rs75404003, and RANKL (zeige TNFSF11 Proteine) rs9594782 single nucleotide poymorphisms may predispose LVH in thalassemia patients.

  10. The expression for RANKL (zeige TNFSF11 Proteine) and OPG and the RANKL/OPG (zeige TNFSF11 Proteine) ratio were not significantly different between symptomatic and asymptomatic periapical lesions.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. The OPG (zeige TNFSF11 Proteine) expression levels decreased while those of RANKL (zeige TNFSF11 Proteine) and RUNX2 (zeige RUNX2 Proteine) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (zeige TNFSF11 Proteine) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. endocortical resorption is driven by reduced OPG (zeige TNFSF11 Proteine) rather than elevated RANKL (zeige TNFSF11 Proteine) expression

  2. Diabetes significantly increased OPG (zeige TNFSF11 Proteine) and the OPG (zeige TNFSF11 Proteine)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Proteine) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Proteine)/TRAIL ratio.

  3. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (zeige TNFSF11 Proteine) interaction and osteoclastogenesis.

  4. OPG (zeige TNFSF11 Proteine) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  5. These data suggested that OPG (zeige TNFSF11 Proteine) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  6. Data show that p38alpha (zeige MAPK14 Proteine) mitogen-activated protein kinase (zeige MAPK1 Proteine) (MAPK (zeige MAPK1 Proteine)) in paired related homeobox 1 (zeige PRRX1 Proteine) protein (Prx1 (zeige PRDX1 Proteine)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  7. OPG (zeige TNFSF11 Proteine) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  8. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  9. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  10. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Genbezeichner und Symbole assoziert mit TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b)
  • osteoprotegerin (LOC100037695)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • OCIF Protein
  • Opg Protein
  • TR1 Protein

Bezeichner auf Proteinebene für TNFRSF11B

osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like , osteoclastogenesis inhibitory factor , tumor necrosis factor receptor superfamily member 11B

GENE ID SPEZIES
464351 Pan troglodytes
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100037695 Ovis aries
4982 Homo sapiens
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
100860896 Capra hircus
100049688 Sus scrofa
523822 Bos taurus
100065885 Equus caballus
18383 Mus musculus
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