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Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Proteine (TNFRSF11B)

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Antikörper (49) und Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFRSF11B 690  
Ratte TNFRSF11B TNFRSF11B 25341 O08727
TNFRSF11B 18383 O08712
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Top Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Proteine auf antikoerper-online.de

Showing 10 out of 13 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_HEK-293 Maus Unkonjugiert 25 μg Anmelden zum Anzeigen 6 bis 8 Tage
129,41 €
Details
HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_Human Cells Rhesusaffen Fc Tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Anmelden zum Anzeigen 7 bis 8 Tage
841,60 €
Details
HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
119,05 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,50 €
Details
HOST_Human Cells Maus Fc Tag SDS-PAGE 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
Details

TNFRSF11B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, ,
Mouse (Murine) , ,
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Am meisten referenzierte Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Proteine

  1. Mouse (Murine) TNFRSF11B Protein expressed in HEK-293 - ABIN2666866 : Boyce, Xing: Biology of RANK, RANKL, and osteoprotegerin. in Arthritis research & therapy 2007 (PubMed)
    Zeige alle 7 Referenzen für ABIN2666866

  2. Rhesus Monkey TNFRSF11B Protein expressed in Human Cells - ABIN2009907 : Simonet, Lacey, Dunstan, Kelley, Chang, Lüthy, Nguyen, Wooden, Bennett, Boone, Shimamoto, DeRose, Elliott, Colombero, Tan, Trail, Sullivan, Davy, Bucay, Renshaw-Gegg, Hughes, Hill, Pattison, Campbell et al.: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. ... in Cell 1997 (PubMed)
    Zeige alle 4 Referenzen für ABIN2009907

  3. Human TNFRSF11B Protein expressed in Human Cells - ABIN2002484 : Yasuda, Shima, Nakagawa, Mochizuki, Yano, Fujise, Sato, Goto, Yamaguchi, Kuriyama, Kanno, Murakami, Tsuda, Morinaga, Higashio: Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. in Endocrinology 1998 (PubMed)
    Zeige alle 4 Referenzen für ABIN2002484

Weitere Proteine zu Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Interaktionspartnern

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Interaktionspartner

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Interaktionspartner

  1. The OPG (zeige TNFSF11 Proteine) expression levels decreased while those of RANKL (zeige TNFSF11 Proteine) and RUNX2 (zeige RUNX2 Proteine) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (zeige TNFSF11 Proteine) mRNA expression.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Interaktionspartner

  1. endocortical resorption is driven by reduced OPG (zeige TNFSF11 Proteine) rather than elevated RANKL (zeige TNFSF11 Proteine) expression

  2. Diabetes significantly increased OPG (zeige TNFSF11 Proteine) and the OPG (zeige TNFSF11 Proteine)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Proteine) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Proteine)/TRAIL ratio.

  3. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (zeige TNFSF11 Proteine) interaction and osteoclastogenesis.

  4. OPG (zeige TNFSF11 Proteine) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  5. These data suggested that OPG (zeige TNFSF11 Proteine) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  6. Data show that p38alpha (zeige MAPK14 Proteine) mitogen-activated protein kinase (zeige MAPK1 Proteine) (MAPK (zeige MAPK1 Proteine)) in paired related homeobox 1 (zeige PRRX1 Proteine) protein (Prx1 (zeige PRDX1 Proteine)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  7. OPG (zeige TNFSF11 Proteine) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  8. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  9. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  10. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Protein Überblick

Protein Überblick

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).

Genbezeichner und Symbole assoziert mit TNFRSF11B

  • basic transcription factor 3 pseudogene 11 (BTF3P11)
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • BTF3L1 Protein
  • HUMBTFB Protein
  • OCIF Protein
  • Opg Protein
  • TNFRSF11B Protein
  • TR1 Protein

Bezeichner auf Proteinebene für TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , osteoprotegerin , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , osteoclastogenesis inhibitory factor

GENE ID SPEZIES
690 Homo sapiens
482025 Canis lupus familiaris
100049688 Sus scrofa
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
18383 Mus musculus
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