Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Proteine (TNFSF8)

The protein encoded by TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Antikörper (148) und Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Kits (45) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFSF8 54313  
TNFSF8 21949 P32972
TNFSF8 944 P32971
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Top Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Proteine auf antikoerper-online.de

Showing 10 out of 23 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_Human Cells Cynomolgus His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
HOST_Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_CHO Cells Maus Unkonjugiert   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
77,65 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Anmelden zum Anzeigen 7 bis 8 Tage
841,60 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_CHO Cells Human His tag   10 μg Anmelden zum Anzeigen 8 bis 11 Tage
438,90 €
Details

TNFSF8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus) ,
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Mouse (Murine) ,
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Human , , , , , , , ,
, , , , ,

Am meisten referenzierte Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Proteine

  1. Mouse (Murine) TNFSF8 Protein expressed in CHO Cells - ABIN2666787 : Croft, Benedict, Ware: Clinical targeting of the TNF and TNFR superfamilies. in Nature reviews. Drug discovery 2013 (PubMed)
    Zeige alle 6 Referenzen für 2666787

  2. Human TNFSF8 Protein expressed in Human Cells - ABIN2001944 : Gruss, Boiani, Williams, Armitage, Smith, Goodwin: Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines. in Blood 1994 (PubMed)
    Zeige alle 5 Referenzen für 2001944

  3. Rat (Rattus) TNFSF8 Protein expressed in Human Cells - ABIN2009208 : Croager, Abraham: Characterisation of the human CD30 ligand gene structure. in Biochimica et biophysica acta 1997 (PubMed)
    Zeige alle 5 Referenzen für 2009208

  4. Cynomolgus TNFSF8 Protein expressed in Human Cells - ABIN2009821 : Wendtner, Schmitt, Gruss, Druker, Emmerich, Goodwin, Hallek: CD30 ligand signal transduction involves activation of a tyrosine kinase and of mitogen-activated protein kinase in a Hodgkin's lymphoma cell line. in Cancer research 1995 (PubMed)
    Zeige alle 5 Referenzen für 2009821

Weitere Proteine zu Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) Interaktionspartnern

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) Interaktionspartner

  1. Data indicate that CD30L/CD30 (zeige TNFRSF8 Proteine) axis plays a modulatory role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE).

  2. Altered expression of CD30L and IL-3 (zeige IL-3 Proteine) may be potential biomarkers for hepatotoxicity induced by D. bulbifera.

  3. role in the maintenance and activation of IL-17A (zeige IL17A Proteine)-producing gammadelta T cells

  4. Interference of the CD30 (zeige TNFRSF8 Proteine)-CD30L pathway reduces atherosclerosis development.

  5. It is shown here that CD30L knock out (KO) mice are highly susceptible to primary infection with Listeria monocytogenes as assessed by the survival rate.

  6. role of CD30L/CD30 (zeige TNFRSF8 Proteine) interactions in allergic rhinitis; results suggest that CD30L plays an important role in allergic rhinitis

  7. Modulation of CD30L/CD30 (zeige TNFRSF8 Proteine) signaling by soluble CD30 (zeige TNFRSF8 Proteine) could be a novel biological therapy for inflammatory diseases associated with Th17 responses.

  8. Studies demonstrate that CD30L/CD30 (zeige TNFRSF8 Proteine) signaling executed by the T-T cell interaction plays a critical role in Th17 cell differentiation.

  9. Characterization of the murine CD30 ligand (CD153) gene: gene structure and expression.

  10. CD30L is required for generation of long-lived memory CD8 (zeige CD8A Proteine)+ T cells; CD30L signaling triggers homing receptors for T(central memory) cells.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) Interaktionspartner

  1. circulant sCD30L is functionally active and that it may favor persistence of active inflammation by inducing apoptosis of CD30 (zeige TNFRSF8 Proteine)(+)T cells, known to down-modulate inflammation in rheumatoid synovitis.

  2. TNFSF8 is an important leprosy T1R susceptibility gene.

  3. The heritability of IgA levels is moderate and can partly be attributable to common variation in the CD30L locus.

  4. soluble apoptosis markers as sFas-L, Caspase-9 (zeige CASP9 Proteine), Caspase-8 (zeige CASP8 Proteine) and sCD153 were significantly higher in stage III obesity patients compared obese patients without food allergy

  5. a novel and unexpected role for CD30 (zeige TNFRSF8 Proteine)/CD30L that contributes to proinflammatory immune responses

  6. The TNFSF8 polymorphisms rs927374 and rs2295800 were associated with neutrophil count. This finding suggests that post-MI inflammatory response is genetically modulated.

  7. Positional candidate gene screening in the SPA2 locus allowed us to identify and replicate an association between a rare SNP located in TNFSF8 and spondylarthritis.

  8. a possible role of novel TNFSF8 variants in susceptibility to lung cancer.

  9. capability to up-regulate expression of CD30 (zeige TNFRSF8 Proteine), release of soluble CD30 (zeige TNFRSF8 Proteine) and production of IL-4 (zeige IL4 Proteine) in pre-activated T cells upon co-culture

  10. only in a subset of both benign and malignant thyroid nodules the interleukin-6/interleukin-6 (zeige IL6 Proteine) receptor (zeige IL6ST Proteine) signal could be induced by the CD30 ligand/CD30 (zeige TNFRSF8 Proteine)

Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TNFSF8

  • tumor necrosis factor (ligand) superfamily, member 8 (Tnfsf8)
  • tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8)
  • CD30L Protein
  • CD30LG Protein
  • CD153 Protein
  • TNFSF8 Protein

Bezeichner auf Proteinebene für TNFSF8

tumor necrosis factor (ligand) superfamily, member 8 , CD30 antigen ligand , CD30 ligand , tumor necrosis factor ligand superfamily member 8 , CD30-L , CD153 antigen

GENE ID SPEZIES
54313 Rattus norvegicus
464686 Pan troglodytes
612608 Canis lupus familiaris
702944 Macaca mulatta
21949 Mus musculus
944 Homo sapiens
683163 Rattus norvegicus
378930 Gallus gallus
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