Tumor Necrosis Factor (Ligand) Superfamily, Member 18 Proteine (TNFSF18)

The protein encoded by TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor (Ligand) Superfamily, Member 18 Antikörper (209) und Tumor Necrosis Factor (Ligand) Superfamily, Member 18 Kits (16) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFSF18 240873 Q7TS55
TNFSF18 8995 Q9UNG2
Ratte TNFSF18 TNFSF18 364031  
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Top Tumor Necrosis Factor (Ligand) Superfamily, Member 18 Proteine auf antikoerper-online.de

Showing 10 out of 37 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,041.49
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
HEK-293 Cells Human DYKDDDDK Tag Flag-tagged GITRL bound to GITR transfected cells. HEK-293 cells were transiently transfected with a construct encoding human GITR full length. At 48hr after transfection, the transfectants were incubated with 5μg/ml of human FLAG-tagged GITRL  protein and followed by flow cytometric analysis with anti-FLAG M2-FITC. 50 μg Anmelden zum Anzeigen 5 bis 8 Tage
$446.25
Details
HEK-293 Human Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$135.88
Details
HEK-293 Cells Maus Fc Tag Immobilized Mouse GITR, His Tag  with a linear range of 0.007-0.256 μg/mL. Mouse GITR Ligand / TNFSF18, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 5 Days
$385.00
Details
Escherichia coli (E. coli) Human Unkonjugiert 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
HEK-293 Cells Maus DYKDDDDK Tag   50 μg Anmelden zum Anzeigen 5 bis 8 Tage
$425.25
Details
HEK-293 Cells Human Fc Tag Human GITR Ligand, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human GITR, His Tag (Cat# GIR-H5228) at 2 μg/mL (100 μl/well) can bind Human GITR Ligand, Fc Tag (Cat# GIL-H526a ) with a linear range of 0.8-25 ng/mL. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$385.00
Details

TNFSF18 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) , ,
, , ,
Human , , , , , , ,
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Weitere Proteine zu Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) Interaktionspartnern

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) Interaktionspartner

  1. the upregulation of IFN-beta (zeige IFNB1 Proteine) in DCs induces the up-regulation of coinhibitory molecules B7H1 (zeige CD274 Proteine) and GITRL, which cause an impaired activation of naive Ag-specific T cells

  2. GITRL expressed on macrophages drives cytokine release and T cell activation, resulting in neuropathic pain via GITR (zeige TNFRSF18 Proteine)-dependent actions. The GITRL-GITR (zeige TNFRSF18 Proteine) pathway might represent a novel target for the treatment of neuropathic pain.

  3. Down-regulation of GITRL enhances CD8 (zeige CD8A Proteine) T cell responses to chronic lymphocytic choriomeningitis virus.

  4. Sjogren's syndrome-like autoimmune sialadenitis in MRL-Faslpr mice is associated with expression of glucocorticoid-induced TNF receptor-related protein (GITR) ligand and 4-1BB ligand (zeige TNFSF9 Proteine).

  5. GITRL triggering in endothelial cells increases leukocyte adhesion and transmigration.

  6. The B7H1 (zeige CD274 Proteine) and GITRL molecules may play an important role in TGF-beta (zeige TGFB1 Proteine)-induced Treg expansion of lung cancer microenvironment.

  7. results demonstrate that enhanced GITR (zeige TNFRSF18 Proteine)/GITRL interactions have a pleiotropic role on the regulation of T-cell responses

  8. B cell expression of GITRL induced Treg proliferation, maintaining their numbers above a threshold required for the prevention of autoimmunity.

  9. Findings suggest GITRL could enhance the immune stimulation of DC and might facilitate the potential development of DCs-based anti-tumor therapies.

  10. GITRL-dependent expansion of Treg within the cornea is one mechanism underlying immune privilege in corneal allografts.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) Interaktionspartner

  1. GITRL levels are significantly elevated in rheumatoid arthritis serum and synovial fluid and are positively correlated with autoantibody production in rheumatoid arthritis, suggesting a role of GITRL in the development of rheumatoid arthritis.

  2. GITRL modulates the activities of p38 MAPK (zeige MAPK14 Proteine) and STAT3 (zeige STAT3 Proteine) to promote Th17 cell differentiation in autoimmune arthritis.

  3. An increase in GITRL may impair the balance of Th17/Treg, and contribute to the pathopoiesis of Hashimoto's thyroiditis.

  4. Our findings indicate the possible involvement of GITR (zeige TNFRSF18 Proteine)-GITRL pathway in the pathogenesis of pSS (zeige CDSN Proteine).

  5. Serum GITRL levels were higher in SLE patients.

  6. Glucocorticoid-induced TNF-related ligand (GITRL) confers pseudoexpression to tumor cells by platelets, which results in GITRL expression by megakaryocytes and their platelet progeny.

  7. observation suggests a link between cytokine-regulated keratinocyte GITRL expression and its role in inflammatory responses in AD

  8. GITRL upregulation induced by IFN-beta (zeige IFNB1 Proteine) on dendritic cells downregulates CTLA-4 (zeige CTLA4 Proteine) on regulatory T (Treg) cells, facilitating proliferation of anergic Treg cells in multiple sclerosis treatment of multiple sclerosis patients.

  9. Although GITR (zeige TNFRSF18 Proteine) transgene costimulation can therapeutically enhance T helper (Th) type 2 cell responses, GITR-GITR (zeige TNFRSF18 Proteine) ligand interactions are not required for development of Th2-mediated resistance or pathology.

  10. GITRL expression on Kupffer cells may mediate acute rejection in liver transplantation

Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Genbezeichner und Symbole assoziert mit TNFSF18

  • tumor necrosis factor (ligand) superfamily, member 18 (Tnfsf18)
  • TNF superfamily member 18 (TNFSF18)
  • TNF superfamily member 18 (Tnfsf18)
  • AITRL Protein
  • GITRL Protein
  • hGITRL Protein
  • TL6 Protein
  • TNLG2A Protein

Bezeichner auf Proteinebene für TNFSF18

GITR ligand , glucocorticoid-induced TNF-related ligand , glucocorticoid-induced-tumor necrosis factor receptor ligand , tumor necrosis factor ligand superfamily member 18 , AITR ligand , activation-inducible TNF-related ligand , glucocorticoid-induced TNFR-related protein ligand , tumor necrosis factor (ligand) superfamily, member 18 , tumor necrosis factor ligand 2A , tumor necrosis factor superfamily member 18

GENE ID SPEZIES
240873 Mus musculus
8995 Homo sapiens
364031 Rattus norvegicus
100855912 Canis lupus familiaris
100060504 Equus caballus
768081 Bos taurus
Ausgewählte Anbieter für Tumor Necrosis Factor (Ligand) Superfamily, Member 18 Proteine (TNFSF18)
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