Tumor Necrosis Factor (Ligand) Superfamily, Member 14 Proteine (TNFSF14)

The protein encoded by TNFSF14 is a member of the tumor necrosis factor (TNF) ligand family. Zusätzlich bieten wir Ihnen TNFSF14 Antikörper (159) und TNFSF14 Kits (32) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TNFSF14 8740 O43557
TNFSF14 301133  
TNFSF14 50930 Q9QYH9
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Showing 10 out of 26 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human GST tag Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag) 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
230,48 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
670,48 €
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Anmelden zum Anzeigen 7 bis 8 Tage
841,60 €
Details
HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details

TNFSF14 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , ,
, , , , , ,
Rat (Rattus)

Mouse (Murine) , ,
,

Am meisten referenzierte TNFSF14 Proteine

  1. Human TNFSF14 Protein expressed in Escherichia coli (E. coli) - ABIN1047820 : Harrop, McDonnell, Brigham-Burke, Lyn, Minton, Tan, Dede, Spampanato, Silverman, Hensley, DiPrinzio, Emery, Deen, Eichman, Chabot-Fletcher, Truneh, Young: Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 2 Referenzen für 1047820

Weitere Proteine zu Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) Interaktionspartnern

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) Interaktionspartner

  1. LIGHT is highly expressed and companied with severe inflammations in patients with coronary disease. LIGHT significantly enhanced inflammation response in oxLDL-induced THP-1 macrophages.

  2. LIGHT and LTBR (zeige LTBR Proteine) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  3. LIGHT, via LTbetaR signaling, may contribute to exacerbation of airway neutrophilic inflammation through cytokine and chemokine (zeige CCL1 Proteine) production by bronchial epithelial cells.

  4. LIGHT controls TSLP (zeige TSLP Proteine) to drive pulmonary fibrosis.

  5. The tumor necrosis factor (zeige TNF Proteine) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  6. proliferation and migration would be enhanced in Tca8113 cells with over-expressed TNFSF14

  7. LIGHT, a TNF (zeige TNF Proteine) superfamily member, is involved in T-cell homeostasis and erosive bone disease associated with rheumatoid arthritis.

  8. Crystal structures of LIGHT and the LIGHT:DcR3 complex reveal the structural basis for the DcR3 (zeige TNFRSF6B Proteine)-mediated neutralization of LIGHT.

  9. regulation by NK cell licensing helps to safeguard against TNFSF14 production in response to healthy tissues.

  10. TNFSF14 has an effect on the activation of basophils and eosinophils interacting with bronchial epithelial cells

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) Interaktionspartner

  1. LIGHT signalling pathway combined with IFN-gamma (zeige IFNG Proteine) induces beta cells apoptosis via an NF-kappaB (zeige NFKB1 Proteine)/Bcl2 (zeige BCL2 Proteine)-dependent mitochondrial pathway.

  2. Together, these results demonstrate that the LIGHT signaling pathway is not only required for inflammatory cytokine production as part of the host response to chlamydial infection, but also influences the differentiation of CD4 (zeige CD4 Proteine)(+) CD25 (zeige IL2RA Proteine)(+) FoxP3 (zeige FOXP3 Proteine)(+) Treg cells, both of which may be essential for control of C. psittaci respiratory tract infection.

  3. These results expose the relevance of LIGHT/LTbetaR/HVEM (zeige TNFRSF14 Proteine) interaction for the potential therapeutic control of the allogeneic immune responses mediated by alloreactive CD8 (zeige CD8A Proteine) T cells that can contribute to prolong allograft survival.

  4. Mechanistically, intratumoral LIGHT induces pericyte differentiation and normalization via Rho kinase (zeige ROCK2 Proteine) signaling. Minute amounts of LIGHT act in a paracrine fashion to trigger an amplifying cascade involving transforming growth factor beta (TGF-beta) from peri (zeige POSTN Proteine)-vascular macrophages.

  5. localized overexpression of Tnfsf14 potently enhances muscle regeneration, and that this regenerative capacity of Tnfsf14 is dependent on Akt (zeige AKT1 Proteine) signaling.

  6. LIGHT-HVEM (zeige TNFRSF14 Proteine) interactions stimulate IL-12 (zeige IL12A Proteine) production by DCs during Leishmania donovani infection. Blockade of LIGHT-LTbetaR interactions dramatically enhanced early anti-parasitic immunity.

  7. LIGHT controls TSLP (zeige TSLP Proteine) to drive pulmonary fibrosis.

  8. The tumor necrosis factor (zeige TNF Proteine) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  9. Although LIGHT is critical for maintenance of primary Th1 (zeige HAND1 Proteine) response, it is dispensable during secondary anti-Leishmania immunity in the presence of functional CD40 (zeige CD40 Proteine) signaling.

  10. LIGHT protein is rapidly and transiently expressed after T-cell activation, and this expression is stronger on CD8 (zeige CD8A Proteine) T cells than on CD4 (zeige CD4 Proteine) T cells

TNFSF14 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Genbezeichner und Symbole assoziert mit TNFSF14

  • tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14)
  • tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14)
  • tumor necrosis factor ligand superfamily, member 14 (LOC100347876)
  • CD258 Protein
  • HVEM-L Protein
  • HVEML Protein
  • LIGHT Protein
  • LTg Protein
  • Ly113 Protein
  • TNFSF14 Protein
  • TR2 Protein

Bezeichner auf Proteinebene für TNFSF14

tumor necrosis factor ligand superfamily, member 14 , tumor necrosis factor (ligand) superfamily, member 14 , delta transmembrane LIGHT , herpes virus entry mediator ligand , herpesvirus entry mediator A , herpesvirus entry mediator ligand , herpesvirus entry mediator-ligand , ligand for herpesvirus entry mediator , tumor necrosis factor ligand superfamily member 14 , tumor necrosis factor receptor-like 2 , tumor necrosis factor superfamily member LIGHT , tumor necrosis factor superfamily member 14 , tumor necrosis factor superfamily, member 14

GENE ID SPEZIES
468687 Pan troglodytes
701451 Macaca mulatta
8740 Homo sapiens
301133 Rattus norvegicus
611306 Canis lupus familiaris
100519468 Sus scrofa
505521 Bos taurus
50930 Mus musculus
100347876 Oryctolagus cuniculus
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