Troponin T2, Cardiac (TNNT2) ELISA Kits

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Zusätzlich bieten wir Ihnen Cardiac Troponin T2 Antikörper (381) und Cardiac Troponin T2 Proteine (36) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top Cardiac Troponin T2 ELISA Kits auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
772,39 €
Details
Ratte 5.5 pg/mL 15.6-1000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
643,39 €
Details
Maus 5.7 pg/mL 15.6-1.000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
609,52 €
Details
Schwein 6.0 pg/mL 15.6-1000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
711,11 €
Details
Huhn 5.86 pg/mL 23.44-1500 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
874,71 €
Details
Kaninchen 6.2 pg/mL 15.62-1000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
643,39 €
Details
Hund 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
874,71 €
Details
Meerschweinchen 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Human 11 pg/mL 15.6-1000 pg/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
653,71 €
Details
Affe 9.375 pg/mL 15.625-1000 pg/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details

Am meisten referenzierte Cardiac Troponin T2 ELISA Kits

  1. Rat (Rattus) Cardiac Troponin T2 ELISA Kit für Sandwich ELISA - ABIN433508 : Zhang, Tang, Tian, Li, Zhang, Jiang, Zhang: Cardioprotective effect of sulphonated formononetin on acute myocardial infarction in rats. in Basic & clinical pharmacology & toxicology 2011 (PubMed)
    Zeige alle 5 Referenzen für 433508

  2. Mouse (Murine) Cardiac Troponin T2 ELISA Kit für Sandwich ELISA - ABIN426397 : Desai, Eblimit, Thevananther, Kosters, Moore, Penny, Karpen: Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis. in Liver international : official journal of the International Association for the Study of the Liver 2015 (PubMed)
    Zeige alle 4 Referenzen für 426397

  3. Human Cardiac Troponin T2 ELISA Kit für Sandwich ELISA - ABIN365988 : Karatas, Baysal, Alp, Toker: Serum tenascin-C: a novel biomarker for diagnosis and predicting prognosis of rheumatic carditis? in Journal of tropical pediatrics 2013 (PubMed)

  4. Pig (Porcine) Cardiac Troponin T2 ELISA Kit für Sandwich ELISA - ABIN1169668 : Kim, Chung, Antonisamy, Lee, Bae: Cardioprotective effect of rhizomes of Acorus gramineus against isoproterenol-induced cardiac damage in pigs. in Cardiovascular toxicology 2014 (PubMed)

Weitere ELISA Kits für Cardiac Troponin T2 Interaktionspartner

Human Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. variants in TNNT2 and BAG3 (zeige BAG3 ELISA Kits) are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  2. Binding of the MBNL zinc fingers to cardiac troponin T pre-mRNA is specific and relatively simple, unlike the complex multiple dimer-trimer stoichiometries postulated in some previous studies.

  3. The measurement of high-sensitivity cardiac troponin T plasma concentration within large nationally-representative surveys such as the Health Survey for England is feasible.

  4. Data suggest that modulation of structural dynamics far from the regulatory Ca2 (zeige CA2 ELISA Kits)+-binding site is the underlying molecular mechanism for many TNNC1 (zeige TNNC1 ELISA Kits) mutations in patients with hypertrophic cardiomyopathies or familial hypertrophic cardiomyopathies; many mutations affect balance between open and closed conformations; troponin I switch peptide [TnI (zeige TNNI2 ELISA Kits)(SW)] switch peptide binds to TNNC1 (zeige TNNC1 ELISA Kits) and stabilizes the open TNNC1 (zeige TNNC1 ELISA Kits) conformation.

  5. Data suggest that the tropomyosin (zeige TPM2 ELISA Kits) overlap region structure and function are affected differentially by a point mutation in cardiac tropomyosin (TPM1, D230N) that is associated with dilated cardiomyopathy as compared to a point mutation in cardiac troponin T (TNNT2, R92L) that is associated with hypertrophic cardiomyopathy.

  6. High T2-weighted signal intensity on cine MRI is associated with elevated troponin T in hypertrophic cardiomyopathy.

  7. The high negative predictive value of preoperative hs-cTnT and NT-proBNP suggest usefulness as a "rule-out" test to confirm low risk of postoperative Myocardial Infarction

  8. Generated is a gene-targeted knock-in murine model of the autosomal dominant Arg141Trp (R141W) mutation in human Tnnt2. Tnnt2 R141W mutation causes a Ca2 (zeige CA2 ELISA Kits)+ desensitization and mice adapt by increasing Ca2 (zeige CA2 ELISA Kits)+-transient amplitudes, which impairs Ca2 (zeige CA2 ELISA Kits)+ handling dynamics, metabolism and responses to beta-adrenergic activation.

  9. A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation.

  10. Our study supports that mutations in MYH7 (zeige MYH7 ELISA Kits) and MYBPC3 (zeige MYBPC3 ELISA Kits) should be the first focus of moleculargenetic analysis in HCM, and that mutations in TNNT2 have a low prevalence in Brazilian population. All mutations detected were missense mutations, whereas two mutations in MYH7 (zeige MYH7 ELISA Kits) had not been described before.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Significant changes in thin filament Ca2 (zeige CA2 ELISA Kits)+-sensitivity, structure and kinetics are brought about through PKC (zeige PKC ELISA Kits) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. TnTA30V mutation attenuated Ca(2 (zeige CA2 ELISA Kits)+)-activated maximal tension and length-mediated cross-bridge recruitment against alpha-myosin (zeige MYH6 ELISA Kits) heavy chain but augmented these parameters against beta-myosin heavy chain (zeige MYH7 ELISA Kits), suggesting divergent contractile phenotypes.

  2. The shift from cTnT exon 5 inclusion to exclusion during development was delayed in the heart of Ts65Dn mice due to Dyrk1A (zeige DYRK1A ELISA Kits) overexpression.

  3. for hypertrophic cardiomyopathy (HCM)-causing mutations in TnT (zeige TNNI1 ELISA Kits), Ca(2 (zeige CA2 ELISA Kits)+)-sensitisation together with uncoupling in vitro is the usual response and both factors may contribute to the HCM phenotype

  4. cardiomyopathy mutation (R97L) in mouse cardiac troponin T has an effect on the muscle length-mediated recruitment of crossbridges and is modified divergently by alpha- and beta-myosin heavy chain (zeige MYH7 ELISA Kits)

  5. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  6. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  7. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  8. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  9. TnT (zeige TNNI1 ELISA Kits) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (zeige MYH6 ELISA Kits) and hypertrophic cardiomyopathy in the presence of MYH7 (zeige MYH7 ELISA Kits).

  10. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

Zebrafish Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (zeige TNNI1 ELISA Kits), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (zeige TPM2 ELISA Kits)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (zeige TNNI1 ELISA Kits) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Genbezeichner und Symbole assoziert mit Troponin T2, Cardiac (TNNT2) ELISA Kits

  • troponin T type 2 (cardiac) (TNNT2) Antikörper
  • troponin T2, cardiac (Tnnt2) Antikörper
  • troponin T type 2 (cardiac) (Tnnt2) Antikörper
  • troponin T type 2 (cardiac) (tnnt2) Antikörper
  • troponin T2a, cardiac (tnnt2a) Antikörper
  • CMH2 Antikörper
  • CMPD2 Antikörper
  • CT3 Antikörper
  • cTnT Antikörper
  • Ctt Antikörper
  • CTTG Antikörper
  • LVNC6 Antikörper
  • RATCTTG Antikörper
  • RCM3 Antikörper
  • tnnt2 Antikörper
  • Tnnt3 Antikörper
  • Tnt Antikörper
  • TnTC Antikörper

Bezeichner auf Proteinebene für Troponin T2, Cardiac (TNNT2) ELISA Kits

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPEZIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
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