anti-Troponin T2, Cardiac (TNNT2) Antikörper

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Zusätzlich bieten wir Ihnen Cardiac Troponin T2 Kits (81) und Cardiac Troponin T2 Proteine (29) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top anti-Cardiac Troponin T2 Antikörper auf antikoerper-online.de

Showing 10 out of 384 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of cTnT expression in H9 (A), 4T1 (B), human heart (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Cat Maus Unkonjugiert EIA, IHC (p), IP, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details
Huhn Maus Unkonjugiert IF, IHC (p) Human Rabbit Heart (formalin-fixed, paraffin-embedded) stained with TNNT2 antibody ABIN462337 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB   0.2 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Huhn Maus Unkonjugiert IF, IHC (p) 250 μL Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Cat Maus Unkonjugiert IHC (p), ELISA Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Cat Maus Unkonjugiert IHC (p), ELISA Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Maus Unkonjugiert EIA, WB 0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$401.50
Details

TNNT2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Cardiac Troponin T2 Antikörper

  1. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody für ICS - ABIN2688864 : Jáchymová, Muravská, Paleček, Kuchynka, Řeháková, Magage, Kr��l, Zima, Horký, Linhart: Genetic variation screening of TNNT2 gene in a cohort of patients with hypertrophic and dilated cardiomyopathy. in Physiological research / Academia Scientiarum Bohemoslovaca 2012 (PubMed)
    Show all 7 Pubmed References

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody für IHC (f), ICS - ABIN2688865 : Lian, Hsiao, Wilson, Zhu, Hazeltine, Azarin, Raval, Zhang, Kamp, Palecek: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 7 Pubmed References

  3. Mammalian Monoclonal Cardiac Troponin T2 Primary Antibody für ELISA (Capture), ELISA - ABIN191341 : Feng, Taggart, Hall, Bryant, Sansone, Kemmerer, Herlich, Lord: Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury. in Clinical chemistry 2005 (PubMed)
    Show all 6 Pubmed References

  4. Human Polyclonal Cardiac Troponin T2 Primary Antibody für IP, IHC - ABIN191343 : Goette, Arndt, Röcken, Staack, Bechtloff, Reinhold, Huth, Ansorge, Klein, Lendeckel: Calpains and cytokines in fibrillating human atria. in American journal of physiology. Heart and circulatory physiology 2002 (PubMed)
    Show all 6 Pubmed References

  5. Fish Monoclonal Cardiac Troponin T2 Primary Antibody für ELISA, WB - ABIN191342 : Hammerer-Lercher, Erlacher, Bittner, Korinthenberg, Skladal, Sorichter, Sperl, Puschendorf, Mair: Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy. in Clinical chemistry 2001 (PubMed)
    Show all 6 Pubmed References

  6. Cow (Bovine) Monoclonal Cardiac Troponin T2 Primary Antibody für ELISA (Detection), ELISA - ABIN191346 : Nakaura, Morimoto, Yanaga, Nakata, Nishi, Imaizumi, Ohtsuki: Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy. in The American journal of physiology 1999 (PubMed)
    Show all 6 Pubmed References

  7. Cow (Bovine) Monoclonal Cardiac Troponin T2 Primary Antibody für ELISA (Capture), ELISA - ABIN191348 : Urasawa, Wada, Machida, Yuasa, Shimatsu, Wakao, Yuasa, Sano, Nonaka, Nakamura, Takeda: Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. in Circulation 2008 (PubMed)
    Show all 6 Pubmed References

  8. Human Monoclonal Cardiac Troponin T2 Primary Antibody für ELISA (Detection), ELISA - ABIN191347 : van den Berg, Abu-Issa, de Boer, Hutson, de Boer, Soufan, Ruijter, Kirby, van den Hoff, Moorman: A caudal proliferating growth center contributes to both poles of the forming heart tube. in Circulation research 2009 (PubMed)
    Show all 6 Pubmed References

Weitere Antikörper gegen Cardiac Troponin T2 Interaktionspartner

Human Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Among patients with chest pain and stable troponin levels, any detectable level of high-sensitivity cardiac troponin is associated with an increased risk of death and cardiovascular disease.

  2. High-sensitivity cTnT measurement increases the detection of perioperative myocardial infarction.

  3. In a heart failure cohort, high sensitivity troponin T serum levels had very significant prognostic value.

  4. Asymptomatic cTnT elevation might be strongly associated with all-cause and cardiovascular mortality in dialysis patients without diabetic nephropathy.

  5. Higher postoperative concentrations of high-sensitivity troponin T are independently associated with all-cause mortality in patients undergoing on-pump cardiac surgery.

  6. variants in TNNT2 and BAG3 (zeige BAG3 Antikörper) are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  7. Binding of the MBNL (zeige MBNL1 Antikörper) zinc fingers to cardiac troponin T pre-mRNA is specific and relatively simple, unlike the complex multiple dimer-trimer stoichiometries postulated in some previous studies.

  8. The measurement of high-sensitivity cardiac troponin T plasma concentration within large nationally-representative surveys such as the Health Survey for England is feasible.

  9. Data suggest that modulation of structural dynamics far from the regulatory Ca2 (zeige CA2 Antikörper)+-binding site is the underlying molecular mechanism for many TNNC1 (zeige TNNC1 Antikörper) mutations in patients with hypertrophic cardiomyopathies or familial hypertrophic cardiomyopathies; many mutations affect balance between open and closed conformations; troponin I switch peptide [TnI (zeige TNNI2 Antikörper)(SW)] switch peptide binds to TNNC1 (zeige TNNC1 Antikörper) and stabilizes the open TNNC1 (zeige TNNC1 Antikörper) conformation.

  10. Data suggest that the tropomyosin (zeige TPM2 Antikörper) overlap region structure and function are affected differentially by a point mutation in cardiac tropomyosin (TPM1, D230N) that is associated with dilated cardiomyopathy as compared to a point mutation in cardiac troponin T (TNNT2, R92L) that is associated with hypertrophic cardiomyopathy.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Significant changes in thin filament Ca2 (zeige CA2 Antikörper)+-sensitivity, structure and kinetics are brought about through PKC (zeige PKC Antikörper) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. TnTA30V mutation attenuated Ca(2 (zeige CA2 Antikörper)+)-activated maximal tension and length-mediated cross-bridge recruitment against alpha-myosin (zeige MYH6 Antikörper) heavy chain but augmented these parameters against beta-myosin heavy chain (zeige MYH7 Antikörper), suggesting divergent contractile phenotypes.

  2. The shift from cTnT exon 5 inclusion to exclusion during development was delayed in the heart of Ts65Dn mice due to Dyrk1A (zeige DYRK1A Antikörper) overexpression.

  3. for hypertrophic cardiomyopathy (HCM)-causing mutations in TnT (zeige TNNI1 Antikörper), Ca(2 (zeige CA2 Antikörper)+)-sensitisation together with uncoupling in vitro is the usual response and both factors may contribute to the HCM phenotype

  4. cardiomyopathy mutation (R97L) in mouse cardiac troponin T has an effect on the muscle length-mediated recruitment of crossbridges and is modified divergently by alpha- and beta-myosin heavy chain (zeige MYH7 Antikörper)

  5. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  6. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  7. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  8. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  9. TnT (zeige TNNI1 Antikörper) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (zeige MYH6 Antikörper) and hypertrophic cardiomyopathy in the presence of MYH7 (zeige MYH7 Antikörper).

  10. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

Zebrafish Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (zeige TNNI1 Antikörper), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (zeige TPM2 Antikörper)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (zeige TNNI1 Antikörper) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Antigen-Profil

Protein Überblick

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Genbezeichner und Symbole assoziert mit TNNT2

  • troponin T2, cardiac type (TNNT2) Antikörper
  • troponin T2, cardiac type (Tnnt2) Antikörper
  • troponin T2, cardiac type L homeolog (tnnt2.L) Antikörper
  • troponin T2, cardiac (Tnnt2) Antikörper
  • troponin T type 2a (cardiac) (tnnt2a) Antikörper
  • CMH2 Antikörper
  • CMPD2 Antikörper
  • CT3 Antikörper
  • cTnT Antikörper
  • Ctt Antikörper
  • CTTG Antikörper
  • LVNC6 Antikörper
  • RATCTTG Antikörper
  • RCM3 Antikörper
  • tnnt2 Antikörper
  • Tnnt3 Antikörper
  • Tnt Antikörper
  • TnTC Antikörper

Bezeichner auf Proteinebene für TNNT2

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPEZIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
Ausgewählte Anbieter für anti-Cardiac Troponin T2 (TNNT2) Antikörper
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