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anti-Troponin T2, Cardiac (TNNT2) Antikörper

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Zusätzlich bieten wir Ihnen Cardiac Troponin T2 Kits (70) und Cardiac Troponin T2 Proteine (39) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top anti-Cardiac Troponin T2 Antikörper auf antikoerper-online.de

Showing 10 out of 372 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Maus Unkonjugiert IF, IHC (p) 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
495,00 €
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Huhn Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
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Cat Maus Unkonjugiert EIA, IHC (p), IP, WB 50 μg Anmelden zum Anzeigen 8 bis 10 Tage
517,00 €
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Cat Maus Unkonjugiert EIA, IHC (p), IP, WB 50 μg Anmelden zum Anzeigen 8 bis 10 Tage
517,00 €
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Rind (Kuh) Maus Unkonjugiert EIA, WB   0.2 mg Anmelden zum Anzeigen 8 bis 10 Tage
363,00 €
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Human Maus Unkonjugiert EIA, IHC (p) 0.25 mg Anmelden zum Anzeigen 8 bis 10 Tage
517,00 €
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Human Maus Unkonjugiert IA, WB   0.2 mg Anmelden zum Anzeigen 2 bis 4 Tage
212,00 €
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Human Maus Unkonjugiert EIA, WB 0.2 mg Anmelden zum Anzeigen 8 bis 10 Tage
396,00 €
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Human Maus Unkonjugiert EIA, FACS, WB 0.1 mL Anmelden zum Anzeigen 8 bis 10 Tage
473,00 €
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TNNT2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Cardiac Troponin T2 Antikörper

  1. Human Polyclonal Cardiac Troponin T2 Primary Antibody für EIA, WB - ABIN951043 : Millat, Chanavat, Créhalet, Rousson: Development of a high resolution melting method for the detection of genetic variations in hypertrophic cardiomyopathy. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für ABIN951043

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody für IF, IHC (p) - ABIN180606 : Malouf, McMahon, Oakeley, Anderson: A cardiac troponin T epitope conserved across phyla. in The Journal of biological chemistry 1992 (PubMed)

  3. Chicken Polyclonal Cardiac Troponin T2 Primary Antibody für WB - ABIN2776953 : Klaassen, Probst, Oechslin, Gerull, Krings, Schuler, Greutmann, Hürlimann, Yegitbasi, Pons, Gramlich, Drenckhahn, Heuser, Berger, Jenni, Thierfelder: Mutations in sarcomere protein genes in left ventricular noncompaction. in Circulation 2008 (PubMed)

  4. Human Monoclonal Cardiac Troponin T2 Primary Antibody für EIA, FACS - ABIN1105666 : Hershberger, Pinto, Parks, Kushner, Li, Ludwigsen, Cowan, Morales, Parvatiyar, Potter: Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. in Circulation. Cardiovascular genetics 2009 (PubMed)

  5. Human Monoclonal Cardiac Troponin T2 Primary Antibody für IA, WB - ABIN265695 : Qiao, Tang, Munske, Dutta, Ivory, Dong: Enhanced fluorescence anisotropy assay for human cardiac troponin I and T detection. in Journal of fluorescence 2011 (PubMed)

Weitere Antikörper gegen Cardiac Troponin T2 Interaktionspartner

Human Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. TNNT2 gene mutation is associated with Early-Onset Hypertrophic Cardiomyopathy.

  2. The results showed that MYBPC3 25-bp deletion polymorphism was significantly associated with elevated risk of left ventricular dysfunction (LVD), while TTN 18 bp I/D, TNNT2 5 bp I/D and myospryn K2906N polymorphisms did not show any significant association with LVD.

  3. A novel heterozygous mutation (MYH7 (zeige MYH7 Antikörper), p.Asn885Thr), and a variant of uncertain significance (TNNT2, p.Arg296His) were identified in 2 patients with familial hypertrophic cardiomyopathy.

  4. Discordant elevation of cTnT in the presence of normal CK plasma levels on admission is associated with increased mortality in STEMI patients undergoing primary PCI (zeige SERPINA5 Antikörper).

  5. High cardiac troponin T expression is associated with heart diseases.

  6. The results presented here have detected important prognostic differences between patients with 1 of the TNNT2 mutations (Arg92Gln) and those with the 5 other TNNT2 mutations. Carriers of the Arg92Gln mutation developed hypertrophic or dilated cardiomyopathy and had a significantly worse prognosis than those with other mutations in TNNT2.

  7. No adverse clinical events or functional changes of the device were noted, even in those with increases in cTnT.

  8. TNNT2 TNNT2

  9. This review summarizes the recent proteomic data on aminoacid sequences of cTnT and cTnI in various species, as well as selected analytical characteristics of human cardiac troponin high-sensitivity assays

  10. High-sensitivity cardiac troponin T could be used as an early biomarker for the risk stratification of patients with type-A acute aortic dissection.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Significant changes in thin filament Ca2 (zeige CA2 Antikörper)+-sensitivity, structure and kinetics are brought about through PKC (zeige PKC Antikörper) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  2. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  3. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  4. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  5. TnT (zeige TNNI1 Antikörper) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (zeige MYH6 Antikörper) and hypertrophic cardiomyopathy in the presence of MYH7 (zeige MYH7 Antikörper).

  6. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

  7. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  8. Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T.

  9. Study is the first to show that the interplay between the N terminus of cTnT and the overlapping ends of contiguous Tm effectuates different states of Tm on the actin filament.

  10. We conclude that the observed clinical severity of the cTnT Delta160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca(2 (zeige CA2 Antikörper)+) homeostasis

Zebrafish Troponin T2, Cardiac (TNNT2) Interaktionspartner

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (zeige TNNI1 Antikörper), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (zeige TPM2 Antikörper)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (zeige TNNI1 Antikörper) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Antigen-Profil

Protein Überblick

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Genbezeichner und Symbole assoziert mit TNNT2

  • troponin T type 2 (cardiac) (TNNT2) Antikörper
  • troponin T2, cardiac (Tnnt2) Antikörper
  • troponin T type 2 (cardiac) (Tnnt2) Antikörper
  • troponin T type 2 (cardiac) (tnnt2) Antikörper
  • troponin T2a, cardiac (tnnt2a) Antikörper
  • CMH2 Antikörper
  • CMPD2 Antikörper
  • CT3 Antikörper
  • cTnT Antikörper
  • Ctt Antikörper
  • CTTG Antikörper
  • LVNC6 Antikörper
  • RATCTTG Antikörper
  • RCM3 Antikörper
  • tnnt2 Antikörper
  • Tnnt3 Antikörper
  • Tnt Antikörper
  • TnTC Antikörper

Bezeichner auf Proteinebene für TNNT2

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPEZIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
Ausgewählte Anbieter für anti-Cardiac Troponin T2 (TNNT2) Antikörper
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