anti-Tribbles Homolog 2 (Drosophila) (TRIB2) Antikörper

TRIB2 encodes one of three members of the Tribbles family. Zusätzlich bieten wir Ihnen Tribbles Homolog 2 (Drosophila) Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRIB2 28951 Q92519
TRIB2 217410 Q8K4K3
TRIB2 313974  
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Top anti-Tribbles Homolog 2 (Drosophila) Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-TRIB2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Liver 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB TRIB2 was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method TRIB2 was detected in paraffin-embedded sections of rat spleen tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Fledermaus Ziege Unkonjugiert IHC (p) Colon, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunofluorescence: TRIB2 Antibody  - Staining of human cell line A-431 shows positivity in cytoplasm and nucleus but excluded from the nucleoli. Western Blot: TRIB2 Antibody  - Analysis in human cell line K562. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to TRIB2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] TRIB2 monoclonal antibody (M04), clone 1B1 Western Blot analysis of TRIB2 expression in Jurkat (ABIN1339540). 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in Microplate Reader by 450 nm Formalin-fixed and paraffin embedded human lung cancer labeled with Anti-TRIB2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of TRIB2 (arrow) using rabbit polyclonal TRIB2 N-term (ABIN652876). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRIB2 gene (Lane 2) . TRIB2 Antibody (N-term) (ABIN652876) IHC analysis in formalin fixed and paraffin embedded mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-TRIB2 mouse monoclonal antibody. (ABIN2452556, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-TRIB2mouse monoclonal antibody. (ABIN2452556, Dilution 1:50) 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
418,10 €
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
Details

TRIB2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Tribbles Homolog 2 (Drosophila) Antikörper

  1. Human Monoclonal TRIB2 Primary Antibody für IHC (p), RNAi - ABIN565396 : Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ... in The Journal of biological chemistry 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TRIB2 Primary Antibody für ICC, IF - ABIN4362344 : Sung, Francis, Arnold, Holland, Ernst, Angyal, Kiss-Toth: Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis. in Biology 2014 (PubMed)

Weitere Antikörper gegen Tribbles Homolog 2 (Drosophila) Interaktionspartner

Xenopus laevis Tribbles Homolog 2 (Drosophila) (TRIB2) Interaktionspartner

  1. tissues expressing the highest levels of Xtrb2 were most markedly affected by morpholino knockdown, with perturbation of neural crest and eye development

Human Tribbles Homolog 2 (Drosophila) (TRIB2) Interaktionspartner

  1. Tumors from resistant patients expressed the lowest levels of TRIB2. Downregulation of TRIB2 contributes to platin-resistance.

  2. our data show that excess p30 (zeige CENPV Antikörper) cooperated with TRIB2 only in the presence of p42 (zeige EPB42 Antikörper) to accelerate acute myeloid leukaemia (AML (zeige RUNX1 Antikörper)), and the direct interaction and degradation of C/EBPa (zeige CEBPA Antikörper) p42 (zeige EPB42 Antikörper) is required for TRIB2-mediated AML (zeige RUNX1 Antikörper).

  3. miR (zeige MLXIP Antikörper)-206 and miR (zeige MLXIP Antikörper)-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 promoter activity through p-Smad3 (zeige SMAD3 Antikörper).

  4. Studied effect of TRIB2 SNP on the expression of genes involved in adaptive thermogenesis using messenger RNAs prepared from adipose tissues of Japanese adults. Of the five thermogenic genes, DIO2 (zeige DIO2 Antikörper), CIDEA (zeige CIDEA Antikörper), PPARGC1A (zeige PPARGC1A Antikörper), and PRDM16 (zeige PRDM16 Antikörper) showed significantly higher transcript levels in SAT of individuals with the AA genotype relative to those with the AT + TT genotype.

  5. Data show that TRIB2-mediated degradation of CDC25C (zeige CDC25C Antikörper) is associated with lysine-48-linked CDC25C (zeige CDC25C Antikörper) polyubiquitination driven by the TRIB2 kinase-like domain.

  6. High TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 (zeige TAL1 Antikörper) complex in T-cell acute lymphoblastic leukemia.

  7. Studies suggest that pseudo-kinase family of tribbles (zeige TRIB1 Antikörper) (TRIB) proteins TRIB1 (zeige TRIB1 Antikörper), TRIB2 and TRIB3 (zeige TRIB3 Antikörper) play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.

  8. Studies suggest that pseudo-kinase family of tribbles (zeige TRIB1 Antikörper) (TRIB) proteins TRIB1 (zeige TRIB1 Antikörper), TRIB2 and TRIB3 (zeige TRIB3 Antikörper) were involved in the pathogenesis of inflammation.

  9. Studies suggest that tribbles homolog 2 (Drosophila) protein (TRIB2) as a meaningful biomarker to both diagnose and stage melanoma.

  10. Studies indicate that the molecular interactions that take place between tribbles homolog 2 (Drosophila) protein (TRIB2) and factors involved in the ubiquitin proteasome system (UPS) are varied and have differential downstream effects.

Mouse (Murine) Tribbles Homolog 2 (Drosophila) (TRIB2) Interaktionspartner

  1. These data indicate that Trib2 has a complex role in the pathogenesis of Notch (zeige NOTCH1 Antikörper)-driven T-ALL, which may vary between different T-ALL subtypes.

  2. TRIB1 (zeige TRIB1 Antikörper) and TRIB3 (zeige TRIB3 Antikörper) are more strongly expressed than TRIB2 in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.

  3. we identify the contribution of dysregulated C/EBPalpha (zeige CEBPA Antikörper) and E2F1 (zeige E2F1 Antikörper) to elevated Trib2 expression and leukemic cell survival

  4. Trib2 transduced hematopoietic stem cells developed acute myeloid leukemia (zeige BCL11A Antikörper).

  5. Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.

  6. Data identify Tribbles homolog 2 as an oncogene (zeige RAB1A Antikörper) that induces acute myelogenous leukemia through a mechanism involving inactivation of C/EBPalpha (zeige CEBPA Antikörper).

  7. describe suppression of adipocyte differentiation by TRBs Trib1 (zeige TRIB1 Antikörper), Trib2, Trib3 (zeige TRIB3 Antikörper)

  8. Mice reconstituted with HSC (zeige FUT1 Antikörper) cotransduced with HoxA9 (zeige HOXA9 Antikörper) and Trib2 had accelerated onset of AML (zeige RUNX1 Antikörper) compared to either gene alone

  9. Linkage of Meis1 (zeige MEIS1 Antikörper) leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3 (zeige CCL3 Antikörper).

  10. These results suggest that Trb2 plays minimal roles during kidney and mouse development.

Tribbles Homolog 2 (Drosophila) (TRIB2) Antigen-Profil

Protein Überblick

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit TRIB2

  • tribbles homolog 2 (Drosophila) (TRIB2) Antikörper
  • tribbles homolog 2 (Drosophila) (trib2) Antikörper
  • tribbles homolog 2 (trib2) Antikörper
  • tribbles homolog 2 (LOC100357208) Antikörper
  • tribbles homolog 2 (Drosophila) (Trib2) Antikörper
  • AW319517 Antikörper
  • C5FW Antikörper
  • GS3955 Antikörper
  • RGD1564451 Antikörper
  • TRB-2 Antikörper
  • TRB2 Antikörper
  • TRIB2 Antikörper
  • xtrb2 Antikörper
  • Xtrbl Antikörper

Bezeichner auf Proteinebene für TRIB2

tribbles homolog 2 (Drosophila) , tribbles homolog 2-like , tribbles homolog 2 , serine/threonine protein kinase , tribbles-like protein 2 , TRB-2

GENE ID SPEZIES
459038 Pan troglodytes
100331041 Danio rerio
394677 Xenopus (Silurana) tropicalis
100357208 Oryctolagus cuniculus
100528799 Ictalurus punctatus
378920 Xenopus laevis
378919 Gallus gallus
28951 Homo sapiens
403884 Canis lupus familiaris
352960 Bos taurus
217410 Mus musculus
313974 Rattus norvegicus
100173599 Pongo abelii
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