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Trefoil Factor 2 Proteine (TFF2)

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Zusätzlich bieten wir Ihnen Trefoil Factor 2 Antikörper (117) und Trefoil Factor 2 Kits (51) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TFF2 7032 Q03403
TFF2 116592 Q09030
TFF2 21785  
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Showing 10 out of 36 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
412,50 €
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
548,57 €
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HOST_Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
667,62 €
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HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
700,95 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
744,97 €
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HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
214,29 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.090,00 €
Details

TFF2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, ,
Rat (Rattus)

Mouse (Murine) ,

Weitere Proteine zu Trefoil Factor 2 (TFF2) Interaktionspartnern

Human Trefoil Factor 2 (TFF2) Interaktionspartner

  1. this work reveals that TFF2 has tumor-suppressor activity, which may, in part, be regulated by SMAD4 (zeige SMAD4 Proteine).

  2. Data indicate that the antitumor activity of trefoil factor 2 (TFF2) is mediated by an interaction with the transcription factor Sp3 (Sp3) in gastric cancer cells.

  3. Data show the important functions of TFF2 in the gastric mucus barrier, mucus epithelia, immune system, central nervous system, and during fertilization. It has been shown to interact with the gastric mucin MUC6 (zeige MUC6 Proteine). [Review]

  4. These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 (zeige TFF1 Proteine) have protective effects for GC and contribute to the development of GC in Korean individuals.

  5. We reproducibly associate higher expression of the ligand-receptor axis of TFF2 and CXCR4 (zeige CXCR4 Proteine) with BRAF (zeige BRAF Proteine) V600E-mutant colon cancer

  6. protease-activated receptor 4 (zeige F2RL3 Proteine) and Trefoil factor 2 are expressed in human colorectal cancer

  7. The structural features of the N-linked N,N'-di-N-acetyllactosediamine-inducing determinant on human TFF2 are discussed.

  8. Human TTF2 (zeige FOXE1 Proteine) is a lectin that binds alpha-GlcNAc-capped mucin 6 (zeige MUC6 Proteine) g with antibiotic activity against Helicobacter pylori.

  9. Significantly higher levels of TFF2 were in patients with Multiple Organ Dysfunction Syndrome.

  10. There is an association between TFF2 and TFF3 (zeige TFF3 Proteine) polymorphisms and risk of atrophic gastritis and gastric cancer in Chinese people.

Pig (Porcine) Trefoil Factor 2 (TFF2) Interaktionspartner

  1. Low intestinal TFF2 expression was measured at early maturation stages. Weaning, however, was associated with a distinct response of increased TFF2 expression, indicating an important role in enhancing mucosal integrity.

Mouse (Murine) Trefoil Factor 2 (TFF2) Interaktionspartner

  1. the Tg(Tff1 (zeige TFF1 Proteine)-CreERT2;Tff2-rtTA;Tff3 (zeige TFF3 Proteine)-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases

  2. Splenic TFF2 is released by vagally modulated memory T cells to suppress expansion of myeloid-derived suppressor cells (MDSC) through CXCR4 (zeige CXCR4 Proteine). TFF2 is important to the anti-inflammatory reflex arc (zeige NOL3 Proteine) and has an essential role in arresting MDSC proliferation.

  3. hnRNP A1 (zeige HNRNPA1 Proteine) improves intestinal injury in anti-CD3 (zeige CD3E Proteine) antibody-induced enteritis mice through the upregulation of TFF2, which regulates apoptosis and enhances epithelial restoration

  4. Overexpressing Tff2 in cultured cells reduced doubling time in vitro and rapidly increased xenograft tumor size in vivo

  5. Epithelial TFF2 is an important endogenous regulator of gut (zeige GUSB Proteine) mucosal homeostasis that can modulate immune and epithelial compartments.

  6. The Tff2 gene is expressed in the hypothalamus and is regulated by food intake. Knockout mice are leaner (zeige CACNA1A Proteine) and have reduced fat mass compared to wild-type.

  7. The increased expression of endogenous TFF2 in response to chronic allergic inflammation is insufficient to prevent the progression of airway inflammation and remodeling in a model of chronic allergic airways disease.

  8. TFF2 functions as a regulator of intestinal homeostasis that suppresses Toxoplasma gondii-driven type 1 inflammation.

  9. TFF2 (trefoil factor 2), an epithelial cell-derived repair molecule, is needed for the control of lung injury caused by the hookworm parasite Nippostrongylus brasiliensis and for type 2 immunity after infection.

  10. results suggest that during retinal cell death periods, requiring a tightly regulated balance between cell survival and cell death, TFF2 acts pro-proliferative and pro-apoptotic at least in developing mouse retinae cultured in vivo

Trefoil Factor 2 (TFF2) Protein Überblick

Protein Überblick

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Genbezeichner und Symbole assoziert mit Trefoil Factor 2 Proteine (TFF2)

  • trefoil factor 2 (TFF2)
  • trefoil factor 2 (Tff2)
  • trefoil factor 2 (tff2)
  • trefoil factor 2 (spasmolytic protein 1) (Tff2)
  • mSP Protein
  • p4 Protein
  • p4-a Protein
  • PSP Protein
  • sml1 Protein
  • SP Protein
  • TFF2 Protein
  • xP4 Protein
  • xp4.1 Protein

Bezeichner auf Proteinebene für Trefoil Factor 2 Proteine (TFF2)

trefoil factor 2 , trefoil factor 2 (spasmolytic protein 1) , trefoil factor family peptide 2 , spasmolysin , spasmolytic polypeptide , spasmolytic protein 1 , pancreatic spasmolytic polypeptide , SP , spasmolytic peptide , spasmolytic peptide 1 , spasmolytic polypeptide 1 , P-domain peptide , TFF p4.1 , putative gastrointestinal growth factor xP4

GENE ID SPEZIES
418534 Gallus gallus
470096 Pan troglodytes
100170653 Felis catus
7032 Homo sapiens
397420 Sus scrofa
116592 Rattus norvegicus
403489 Canis lupus familiaris
616105 Bos taurus
101787738 Cavia porcellus
378510 Xenopus laevis
21785 Mus musculus
Ausgewählte Anbieter für Trefoil Factor 2 Proteine (TFF2)
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