Transmembrane Protein 66 Proteine (TMEM66)

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. Zusätzlich bieten wir Ihnen TMEM66 Antikörper (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TMEM66 51669 Q96BY9
TMEM66 67887 Q8R3Q0
TMEM66 290796 Q6AYN2
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top TMEM66 Proteine auf antikoerper-online.de

Showing 4 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,649.05
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,315.50
Details

TMEM66 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,
Rat (Rattus)

Weitere Proteine zu Transmembrane Protein 66 (TMEM66) Interaktionspartnern

Human Transmembrane Protein 66 (TMEM66) Interaktionspartner

  1. These findings suggest that the surface location of SARAF is dependent on the expression of STIM1 (zeige STIM1 Proteine) in the plasma membrane.

  2. SARAF modulates TRPC1 (zeige TRPC1 Proteine), but not TRPC6 (zeige TRPC6 Proteine), channel function in a STIM1 (zeige STIM1 Proteine)-independent manner

  3. SARAF overexpression attenuated store operated Ca2 (zeige CA2 Proteine)+ entry and the STIM1 (zeige STIM1 Proteine)-Orai1 interaction in cells endogenously expressing STIM1 (zeige STIM1 Proteine) and Orai1 while RNAi-mediated SARAF silencing induced opposite effects.

  4. SARAF is constitutively expressed in the plasma membrane and interacts with Orai1.

  5. Deletion of STIM1 (zeige STIM1 Proteine)(448-490) and, in particular, STIM1 (zeige STIM1 Proteine)(447-460) and STIM1 (zeige STIM1 Proteine)(475-490) markedly enhances interaction of SARAF with STIM1 (zeige STIM1 Proteine).

  6. Store-operated Ca2 (zeige CA2 Proteine)+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.

  7. Study shows that SARAF is an endoplasmic reticulum resident protein, which responds to cytosolic Ca2 (zeige CA2 Proteine)+ elevation after ER Ca2 (zeige CA2 Proteine)+ refilling by promoting a slow inactivation process of STIM2 (zeige Stim2 Proteine)-dependent basal SOCE activity, as well as STIM1 (zeige STIM1 Proteine)-mediated SOCE activity.

TMEM66 Protein Überblick

Protein Überblick

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)- dependent SOCE activity (By similarity).

Genbezeichner und Symbole assoziert mit TMEM66

  • store-operated calcium entry associated regulatory factor (SARAF)
  • store-operated calcium entry-associated regulatory factor (Saraf)
  • store-operated calcium entry-associated regulatory factor (saraf)
  • store-operated calcium entry-associated regulatory factor S homeolog (saraf.S)
  • transmembrane protein 66 (MCYG_05410)
  • transmembrane protein 66 (MGYG_06464)
  • transmembrane protein 66 (Tsp_10089)
  • store-operated calcium entry associated regulatory factor (saraf)
  • store-operated calcium entry associated regulatory factor (Saraf)
  • 1810045K07Rik Protein
  • FOAP-7 Protein
  • SARAF Protein
  • TMEM66 Protein
  • XTP3 Protein

Bezeichner auf Proteinebene für TMEM66

HBV X-transactivated gene 3 protein , HBV XAg-transactivated protein 3 , SARAF long isoform , SARAF short isoform , SOCE-associated regulatory factor , protein FOAP-7 , store-operated calcium entry-associated regulatory factor , arrestin-E , transmembrane protein 66 , Transmembrane protein 66

GENE ID SPEZIES
51669 Homo sapiens
67887 Mus musculus
290796 Rattus norvegicus
422624 Gallus gallus
464092 Pan troglodytes
482878 Canis lupus familiaris
515461 Bos taurus
693452 Macaca mulatta
767649 Danio rerio
779232 Xenopus laevis
9228751 Arthroderma otae CBS 113480
10027179 Arthroderma gypseum CBS 118893
10905752 Trichinella spiralis
100154322 Sus scrofa
100174030 Pongo abelii
100195167 Salmo salar
100730514 Cavia porcellus
100338803 Oryctolagus cuniculus
101925363 Macaca fascicularis
Ausgewählte Anbieter für TMEM66 Proteine (TMEM66)
Haben Sie etwas anderes gesucht?