Transmembrane Protein 66 (TMEM66) ELISA Kits

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. Zusätzlich bieten wir Ihnen TMEM66 Antikörper (27) und TMEM66 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human TMEM66 TMEM66 51669 Q96BY9
Anti-Maus TMEM66 TMEM66 67887 Q8R3Q0
Anti-Ratte TMEM66 TMEM66 290796 Q6AYN2
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Weitere ELISA Kits für TMEM66 Interaktionspartner

Human Transmembrane Protein 66 (TMEM66) Interaktionspartner

  1. These findings suggest that the surface location of SARAF is dependent on the expression of STIM1 (zeige STIM1 ELISA Kits) in the plasma membrane.

  2. SARAF modulates TRPC1 (zeige TRPC1 ELISA Kits), but not TRPC6 (zeige TRPC6 ELISA Kits), channel function in a STIM1 (zeige STIM1 ELISA Kits)-independent manner

  3. SARAF overexpression attenuated store operated Ca2 (zeige CA2 ELISA Kits)+ entry and the STIM1 (zeige STIM1 ELISA Kits)-Orai1 (zeige ORAI1 ELISA Kits) interaction in cells endogenously expressing STIM1 (zeige STIM1 ELISA Kits) and Orai1 (zeige ORAI1 ELISA Kits) while RNAi-mediated SARAF silencing induced opposite effects.

  4. SARAF is constitutively expressed in the plasma membrane and interacts with Orai1 (zeige ORAI1 ELISA Kits).

  5. Deletion of STIM1 (zeige STIM1 ELISA Kits)(448-490) and, in particular, STIM1 (zeige STIM1 ELISA Kits)(447-460) and STIM1 (zeige STIM1 ELISA Kits)(475-490) markedly enhances interaction of SARAF with STIM1 (zeige STIM1 ELISA Kits).

  6. Store-operated Ca2 (zeige CA2 ELISA Kits)+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.

  7. Study shows that SARAF is an endoplasmic reticulum resident protein, which responds to cytosolic Ca2 (zeige CA2 ELISA Kits)+ elevation after ER Ca2 (zeige CA2 ELISA Kits)+ refilling by promoting a slow inactivation process of STIM2 (zeige Stim2 ELISA Kits)-dependent basal SOCE activity, as well as STIM1 (zeige STIM1 ELISA Kits)-mediated SOCE activity.

TMEM66 Antigen-Profil

Beschreibung des Gens

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)- dependent SOCE activity (By similarity).

Genbezeichner und Symbole assoziert mit TMEM66

  • transmembrane protein 66 (TMEM66) Antikörper
  • zgc:153286 (zgc:153286) Antikörper
  • transmembrane protein 66 (tmem66) Antikörper
  • transmembrane protein 66 (MCYG_05410) Antikörper
  • transmembrane protein 66 (MGYG_06464) Antikörper
  • transmembrane protein 66 (Tsp_10089) Antikörper
  • Transmembrane protein 66 (tmm66) Antikörper
  • transmembrane protein 66 (Tmem66) Antikörper
  • 1810045K07Rik Antikörper
  • FOAP-7 Antikörper
  • SARAF Antikörper
  • tmem66 Antikörper
  • XTP3 Antikörper

Bezeichner auf Proteinebene für TMEM66

transmembrane protein 66 , SOCE-associated regulatory factor , store-operated calcium entry-associated regulatory factor , Transmembrane protein 66 , HBV X-transactivated gene 3 protein , HBV XAg-transactivated protein 3 , SARAF long isoform , SARAF short isoform , protein FOAP-7 , arrestin-E

GENE ID SPEZIES
422624 Gallus gallus
464092 Pan troglodytes
482878 Canis lupus familiaris
693452 Macaca mulatta
767649 Danio rerio
779232 Xenopus laevis
9228751 Arthroderma otae CBS 113480
10027179 Arthroderma gypseum CBS 118893
10905752 Trichinella spiralis
100154322 Sus scrofa
100174030 Pongo abelii
100195167 Salmo salar
51669 Homo sapiens
67887 Mus musculus
290796 Rattus norvegicus
515461 Bos taurus
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