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Transmembrane Protein 38B Proteine (TMEM38B)

TMEM38B encodes an intracellular monovalent cation channel that functions in maintenance of intracellular calcium release. Zusätzlich bieten wir Ihnen Transmembrane Protein 38B Antikörper (20) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TMEM38B 55151 Q9NVV0
TMEM38B 52076 Q9DAV9
Ratte TMEM38B TMEM38B 362521 Q68FV1
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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TMEM38B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Transmembrane Protein 38B (TMEM38B) Interaktionspartnern

Human Transmembrane Protein 38B (TMEM38B) Interaktionspartner

  1. TMEM38B mutations could lead to a rare form of OI, with an autosomal recessive pattern of inheritance. We identified two novel mutations (c.455-7T>G in intron 3 and c.507G>A in exon 4) in TMEM38B in three Chinese children with OI. The two mutations created a new acceptor splice site (p.R151_G152insVL) and a novel downstream termination codon (p.W169X), respectively

  2. Absence of TMEM38B causes osteogenesis imperfecta (zeige COL1A2 Proteine) by dysregulation of calcium flux kinetics in the endoplasmic reticulum, impacting multiple collagen-specific chaperones and modifying enzymes.

  3. A deletion mutation in TMEM38B associated with autosomal recessive osteogenesis imperfecta (zeige COL1A2 Proteine).

  4. TMEM38B is a novel candidate gene for autosomal recessive Osteogenesis imperfecta (zeige COL1A2 Proteine) (OI). Future studies are needed to explore fully the contribution of this gene to autosomal recessive Osteogenesis imperfecta (zeige COL1A2 Proteine) (OI) in other populations.

Mouse (Murine) Transmembrane Protein 38B (TMEM38B) Interaktionspartner

  1. This mini-review focuses on the essential role of TRIC-B channels in bone ossification.

  2. Study found that a simplified, linear, six-state gating model best encompasses the complexity of the subconductance gating behavior of TRIC-B channels

  3. Rapid transitions between TRIC-B sub-conductance states prevented development of reliable gating models.

  4. TRIC-A (zeige TMEM38A Proteine) and TRIC-B seem to have differential functions in Ca(2 (zeige CA2 Proteine)+) signaling in excitable and nonexcitable cells.

  5. TRIC (zeige MARVELD2 Proteine) channels are likely to act as counter-ion channels that function in synchronization with Ca2 (zeige CA2 Proteine)+ release from intracellular stores

  6. TRIC-B-knockout neonates were cyanotic owing to respiratory failure and died shortly after birth. In mutant neonates, the deflated lungs exhibited severe histological defects, and alveolar type II epithelial cells displayed ultrastructural abnormalities.

Transmembrane Protein 38B (TMEM38B) Protein Überblick

Protein Überblick

This gene encodes an intracellular monovalent cation channel that functions in maintenance of intracellular calcium release. Mutations in this gene may be associated with autosomal recessive osteogenesis.

Genbezeichner und Symbole assoziert mit TMEM38B

  • transmembrane protein 38B (tmem38b)
  • transmembrane protein 38B (TMEM38B)
  • transmembrane protein 38B (tmem38b-b)
  • transmembrane protein 38B (Tmem38b)
  • 1600017F22Rik Protein
  • AA437809 Protein
  • AV051057 Protein
  • bA219P18.1 Protein
  • C9orf87 Protein
  • D4Ertd89e Protein
  • DKFZp469C0220 Protein
  • mg33b Protein
  • MGC83592 Protein
  • OI14 Protein
  • RGD1305703 Protein
  • TRIC-B Protein
  • TRICB Protein
  • zgc:55815 Protein

Bezeichner auf Proteinebene für TMEM38B

TRIC-B , TRICB , trimeric intracellular cation channel type B , transmembrane protein 38B , trimeric intracellular cation channel type B-B , TRICB-B , TRIC-B-B , transmembrane protein 38B-B , trimeric intracellular cation channel type B-like , Mitsugumin33B , mitsugumin-33B

GENE ID SPEZIES
393145 Danio rerio
427305 Gallus gallus
444435 Xenopus laevis
464635 Pan troglodytes
548881 Xenopus (Silurana) tropicalis
715679 Macaca mulatta
100153669 Sus scrofa
100173766 Pongo abelii
55151 Homo sapiens
52076 Mus musculus
362521 Rattus norvegicus
615646 Bos taurus
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