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TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. Zusätzlich bieten wir Ihnen TRPM5 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Rat (Rattus) Polyclonal TRPM5 Primary Antibody für IHC, WB - ABIN446170
Delgiorno, Hall, Takeuchi, Pan, Halbrook, Washington, Olive, Spence, Sipos, Wright, Wells, Crawford: Identification and manipulation of biliary metaplasia in pancreatic tumors. in Gastroenterology 2013
Our results suggest roles of TRPM3 (zeige TRPM3 Antikörper) and TRPM5 gene variants in the susceptibility to or clinical expression of Systemic sclerosis
The PKC (zeige PRRT2 Antikörper)-dependent effect of GLP-1 (zeige GCG Antikörper) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (zeige TRPM4 Antikörper) and TRPM5 channels by mobilization of intracellular Ca(2 (zeige CA2 Antikörper)+) from thapsigargin-sensitive Ca(2 (zeige CA2 Antikörper)+) stores
In a Turkish population, genetic polymorphism in TRPM5 genes modify individual susceptibility to metabolic syndrome.
TRPM5-mediated Na(+) entry to promote Ca(2+) uptake via an NCX to trigger MUC5AC secretion
TrpM5 expression was similar throughout the olfactory glomeruli.
The TRPM5 gene rs34551253 (Ala456Thr) polymorphism may be associated with increased risk of developing primary open angle glaucoma in the Turkish population.
AZIN1 (zeige AZIN1 Antikörper) rs2679757 and TRPM5 rs886277 are associated with the risk of HBV-related liver cirrhosis in Chinese.
extracellular Zn(2+) inhibits TRPM5 channels, and the residues in the outer pore loop of TRPM5 are critically involved in the inhibition.
common TRPM5 variants are likely to be associated with prediabetic phenotypes; and this may in turn contribute to the development of type 2 diabetes mellitus
results suggest TRPM5 may play a role in upregulating endogenous expression of TRPA1 (zeige TRPA1 Antikörper), that TRPA1 (zeige TRPA1 Antikörper) activation may be an additional trigger for co-expressed calcium-dependent ion channels such as TRPM5, and that TRPM5 may amplify responses to TRPA1 (zeige TRPA1 Antikörper) ligands
This study demonstrate that Trpm5 is transiently expressed in a subpopulation of mature OSNs in the embryonic olfactory epithelium, indicating that Trpm5 channels could play a specific role in utero during a narrow developmental time window.
The PKC (zeige PKC Antikörper)-dependent effect of GLP-1 (zeige GCG Antikörper) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (zeige TRPM4 Antikörper) and TRPM5 channels by mobilization of intracellular Ca(2 (zeige CA2 Antikörper)+) from thapsigargin-sensitive Ca(2 (zeige CA2 Antikörper)+) stores
The present findings confirm and extend our recent findings that Trpm5 KO mice express significant preferences for 8% glucose and galactose.
Skn-1a (zeige POU2F3 Antikörper) is expressed in a minority of Mash1 (zeige ASCL1 Antikörper)-positive olfactory progenitor cells and a majority of Trpm5-expressing microvillous cells in the main olfactory epithelium.
The Trpm5 (but not T1r3 (zeige TAS1R3 Antikörper)) signaling is essential for starch preference, Trpm5 KO mice can learn to prefer starch based on its postoral effects.
This study show that olfactory sensory neurons expressing TRPM5 respond to pheromones, but not to regular odors through the opening of CNG (zeige CNGA1 Antikörper) channels leading to Ca2 (zeige CA2 Antikörper)+ gating of TRPM5
Evidence suggests that TRPM5 plays a role in mediating transduction for putative pheromones under conditions of reduced chemosensory input.
The results suggest that pharmacological or genetic alteration of TRPM5 activity modulates the benzamil-insensitive NaCl chorda tympani response and its modulation by TRPV1 (zeige TRPV1 Antikörper) agonists.
The findings of this study indicated that T1r3 (zeige TAS1R3 Antikörper) and Trpm5 play critical roles in carbohydrate-induced dietary obesity.
There may be a TRPM5-independent transduction pathway for detecting the taste of sweetening substances.
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
transient receptor potential cation channel, subfamily M, member 5
, transient receptor potential cation channel subfamily M member 5-like
, MLSN1 and TRP-related
, MLSN1- and TRP-related gene 1 protein
, long transient receptor potential channel 5
, transient receptor potential cation channel subfamily M member 5
, long transient receptor potential-related channel 5