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TRPC4 encodes a member of the canonical subfamily of transient receptor potential cation channels. Zusätzlich bieten wir Ihnen TRPC4 Antikörper (127) und TRPC4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
STIM1L (zeige STIM1 ELISA Kits) and TRPC1 (zeige TRPC1 ELISA Kits)/4 are working together in myotubes to ensure efficient store refilling and a proper differentiation program.
These findings suggest identification of an important experimental tool compound, which has much higher potency for inhibiting TRPC1 (zeige TRPC1 ELISA Kits)/4/5 channels than previously reported agents, impressive specificity, and graded subtype selectivity within the TRPC1 (zeige TRPC1 ELISA Kits)/4/5 channel family.
silencing of TRPC4 alleviates angiogenesis induced by oxidized low-density lipoprotein in human coronary artery endothelial cells through inactivation of VEGF (zeige VEGFA ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits).
slow phase of Gi/o-mediated TRPC4 activation was diminished by inhibiting RhoA (zeige RHOA ELISA Kits) or enhancing PLCdelta function
Studies indicate potential roles for Rasd1 (zeige RASD1 ELISA Kits) small G protein (zeige RAC2 ELISA Kits) and leptin (zeige LEP ELISA Kits) in TRPC4 cation channel (zeige TRPV1 ELISA Kits) activation.
Galpha (zeige SUCLG1 ELISA Kits)(i2) activates the TRPC4 channel by direct binding.
This study identifies a novel role for TRPC4 in the regulation of autophagy in vascular endothelial cells.
The higher amplitude of store-operated Ca2 (zeige CA2 ELISA Kits)+ entry was associated to the over-expression for Stim2 (zeige Stim2 ELISA Kits), Orai2 (zeige ORAI2 ELISA Kits)-3, and TRPC1 (zeige TRPC1 ELISA Kits) while Stim2 (zeige Stim2 ELISA Kits) levels remained constant and Stim1 (zeige STIM1 ELISA Kits), Orai1 (zeige ORAI1 ELISA Kits), Orai3 (zeige ORAI3 ELISA Kits), TRPC1 (zeige TRPC1 ELISA Kits) and TRPC4 proteins were over-expressed in primary myelofibrosis.
a membrane-targeting domain of the transient receptor potential canonical (TRPC)4 channel unrelated to its formation of a tetrameric structure
Tarbp2 (zeige TARBP2 ELISA Kits) binding to TRPC4 promotes changes of cytosolic Ca(2 (zeige CA2 ELISA Kits)+) and, thereby, leads to a dynamic regulation of Dicer (zeige DICER1 ELISA Kits) activity, essentially at low endogenous Dicer (zeige DICER1 ELISA Kits) concentrations.
These results indicate the contribution of heteromultimeric channels from TRPC1 (zeige TRPC1 ELISA Kits), TRPC4, and TRPC5 (zeige TRPC5 ELISA Kits) subunits to the regulation of mechanisms underlying spatial working memory and flexible relearning by facilitating proper synaptic transmission in hippocampal neurons.
the antidepressant and anxiolytic-like effects of a newly identified TRPC4/C5 inhibitor, M084.
TRPC4 knockdownsuppressed the activation of ERK (zeige EPHB2 ELISA Kits), p38 MAPK (zeige MAPK14 ELISA Kits) and AKT (zeige AKT1 ELISA Kits) signalingpathway.
Changes in ion selectivity and pore dilation of the TRPC4 channel elicited by the Galphai2 (zeige GNAI2 ELISA Kits) subunit, were studied.
Constitutive ablation of TRPC4 in the amygdala is associated with diminished anxiety levels.
Data suggest that TRPC1 (zeige TRPC1 ELISA Kits) and TRPC4 are involved in the sprouting of sensory neurons following bladder cystitis, which leads to overactive bladder disease.
Data indicate that kisspeptin activates TRPC4 channels through PIP(2) depletion and cSrc tyrosine kinase activation in GnRH neurons.
the S4-S5 linker is a critical constituent of TRPC4/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.
The results of this study suggested that TRPC4, TRPM4 (zeige TRPM4 ELISA Kits), TRPM8 (zeige TRPM8 ELISA Kits) and TRPV1 (zeige TRPV1 ELISA Kits), showed statistically significant variation in mRNA levels between DRGs from different segments, suggesting ganglion-specific regulation of TRP (zeige TYRP1 ELISA Kits) channel gene expression.
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
transient receptor potential 4
, transient receptor potential cation channel, subfamily C, member 5
, transient receptor potential cation channel, subfamily C, member 4
, short transient receptor potential channel 4-like
, short transient receptor potential channel 4
, trp-related protein 4
, capacitative calcium entry channel Trp4
, putative capacitative calcium entry channel
, receptor-activated cation channel TRP4
, transient receptor protein 4
, capacitative calcium entry channel 1
, transient receptor potential channel 4
, transient receptor potential protein 4
, transient receptor potential cation channel TRPC4 middle region 2