anti-Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Antikörper

The structure of the protein encoded by TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. Zusätzlich bieten wir Ihnen TRPA1 Kits (8) und TRPA1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRPA1 8989 O75762
TRPA1 277328 Q8BLA8
TRPA1 312896 Q6RI86
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Top anti-TRPA1 Antikörper auf antikoerper-online.de

Showing 10 out of 95 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, IHC, WB <b>WB Suggested Anti-TRPA1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Stomach 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, WB Detection of TRPA1 in human brain membrane fraction using 2ug/ml of ABIN258315. Staining TRPA1 in mouse intestine using ABIN258315. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Maus Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: TRPA1 Antibody [ABIN4075369] - mouse brain lysate (reduced, denatured) using Rabbit antibody to 4th cytoplasmic loop of TRPA1 (ANKTM1): whole serum at 1:1000 dilution. Western Blot: TRPA1 Antibody [ABIN4075369] - Mouse brain lysate using Rabbit antibody to TRPA1 at 1 : 500 dilution incubated overnight at 4C. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Meerschweinchen Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: TRPA1 Antibody [ABIN4093041] - IF on vagal nodose ganglia. Image from verified customer review. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Ratte Kaninchen Unkonjugiert IHC, WB WB on mouse brain lysate (reduced, denatured) using Rabbit antibody to 4th cytoplasmic loop of TRPA1 (ANKTM1): whole serum (ABIN351100) at 1 : 1000 dilution. WB on mouse brain lysate using Rabbit antibody to TRPA1  at 1 : 500 dilution incubated overnight at 4C. 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Human Kaninchen Unkonjugiert IHC (p) 50 μg Anmelden zum Anzeigen 3 bis 4 Tage
$560.35
Details
Human Kaninchen Unkonjugiert IHC (p), WB TRPA1 antibody  ABIN1104836 (5 ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human skeletal muscle, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-TRPA1 antibody  ABIN1049431 IHC staining of human ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Gibbon Kaninchen Unkonjugiert IHC 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$550.00
Details

TRPA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TRPA1 Antikörper

  1. Guinea Pig Polyclonal TRPA1 Primary Antibody für ICC, IHC (fro) - ABIN258315 : Yu, Gao, Peterson, Ouyang: TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus. in American journal of physiology. Gastrointestinal and liver physiology 2009 (PubMed)
    Show all 15 Pubmed References

  2. Cow (Bovine) Polyclonal TRPA1 Primary Antibody für IF, IHC - ABIN2776190 : Chen, Zhang, Kort, Huth, Sun, Miesbauer, Cassar, Neelands, Scott, Moreland, Reilly, Hajduk, Kym, Hutchins, Faltynek: Molecular determinants of species-specific activation or blockade of TRPA1 channels. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)
    Show all 5 Pubmed References

  3. Guinea Pig Polyclonal TRPA1 Primary Antibody für ICC, IF - ABIN409304 : Coavoy-Sánchez, Rodrigues, Teixeira, Soares, Torregrossa, Wood, Whiteman, Costa, Muscará: Hydrogen sulfide donors alleviate itch secondary to the activation of type-2 protease activated receptors (PAR-2) in mice. in Pharmacological research 2016 (PubMed)
    Show all 2 Pubmed References

  4. Mouse (Murine) Polyclonal TRPA1 Primary Antibody für IHC, IHC (p) - ABIN407536 : Zhang, Wickley, Sinha, Bratz, Damron: Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons. in Anesthesiology 2011 (PubMed)

  5. Guinea Pig Polyclonal TRPA1 Primary Antibody für IHC (fro), IHC (p) - ABIN409428 : Okubo, Matsumura, Kawaishi, Aoki, Matsunami, Okawa, Sekiguchi, Kawabata: Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice. in British journal of pharmacology 2012 (PubMed)

  6. Guinea Pig Polyclonal TRPA1 Primary Antibody für ICC, IF - ABIN4362896 : Hidaka, Ogawa, Kobayashi, Suzuki, Funayama, Nagashima, Fujimura, Aiba, Nakayama, Okuyama, Yamamoto: The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. in Nature immunology 2016 (PubMed)

  7. Human Polyclonal TRPA1 Primary Antibody für IHC (p) - ABIN2476975 : Story, Gereau: Numbing the senses: role of TRPA1 in mechanical and cold sensation. in Neuron 2006 (PubMed)

Weitere Antikörper gegen TRPA1 Interaktionspartner

Zebrafish Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. Zebrafish TRPA1a is specialized for chemical sensing, whereas zTRPA1b responds to thermal stimuli.

  2. Inhibition of TRPA1 protein expression in zebrafish and mouse inner ears inhibits receptor cell function

  3. Larvae heterozygous for mutations in trpa1a respond to mustard oil to an extent similar to that of their wild-type siblings.

Fruit Fly (Drosophila melanogaster) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. Rh5 (zeige RHO Antikörper) and Rh6 (zeige RHO Antikörper) were required in trpA1-expressing neurons in the brain, ventral nerve cord, and body wall. Because Rh1 (zeige RHO Antikörper) contributes to thermal selection in the comfortable range during the early to mid-third-instar stage, fine thermal discrimination depends on multiple rhodopsins.

  2. These findings demonstrate that Drosophila detects bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.

  3. Collectively, TRPA1 A isoform rapidly responds to natural sunlight intensities through its nucleophile sensitivity as a receptor of photochemically generated radicals, leading to an acute light-induced behavioral shift in Drosophila.

  4. H2O2-sensitive dTRPA1 isoforms promote avoidance of UV when adult Drosophila females are selecting sites for egg-laying.

  5. study concludes that the TRPA1 channel is not required for temperature synchronization but instead is required to repress activity during the warm part of the day

  6. Contribution of Drosophila TRPA1 to Metabolism.

  7. Citronellal can promote feeding deterrence of fruit flies through direct action on gustatory dTRPA1, revealing the first isoform-specific function for TRPA1(A).

  8. Recent work has uncovered the Transient Receptor Potential (TRP) channels TRPA1 mediating fly thermosensation.

  9. our results propose that the uracil/Duox (zeige DUOX1 Antikörper) pathway promotes bacteria expulsion from the gut (zeige GUSB Antikörper) through the HOCl-sensitive receptor, TRPA1(A)10b, thereby minimizing the chances that bacteria adapt to survive host defense systems.

  10. The mechanosensory channel, Piezo, has been identifieded in larval drosophila dorsal bipolar dendritic sensory neurons, with TRPA1 playing a subsidiary role.

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. TRPA1 activation suppresses gastric accommodation by increasing gastric tone through cholinergic neuronal pathways.

Caenorhabditis elegans (C. elegans) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. Study reveals that TRPA-1, a cold-sensitive TRP channel, detects temperature drop in the environment to extend lifespan. This effect requires cold-induced, TRPA-1-mediated calcium influx and a calcium-sensitive PKC that signals to the transcription factor DAF-16/FOXO.

  2. harsh touch specifically required the DEG/ENaC proteins MEC-10 and DEGT-1 (F25D1.4), which represent putative components of a harsh touch mechanotransduction complex; responses to cold required the TRPA-1 channel and were MEC-10 and DEGT-1 independent

  3. This study demonstrates that trpa-1 encodes an ion channel that can be activated in response to mechanical pressure and is required for mechanosensory neuron function.

Human Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. neuronal effects of vinca alkaloids require the transient receptor potential ankyrin-1 (TrpA1) channel, and the hypersensitization to painful stimuli in response to the acute exposure to vinca alkaloids is reduced in TrpA1 mutant flies and mice. These findings demonstrate the direct excitation of sensory neurons by CIPN-causing chemotherapy drugs, and identify TrpA1 as an important target during the pathogenesis of CIPN

  2. The TRPA1 cation channel (zeige TRPV1 Antikörper) was found to be functionally expressed in primary human osteoarthritis chondrocytes, which is an original finding

  3. The findings of this study support the notion that epigenetic regulation of TRPA1 seems to regulate thermal and mechanical pain sensitivities.

  4. We provided evidence for the extraneuronal presence and upregulation of the proinflammatory TRPA1 receptor in buccal samples of patients with OLP. This may implicate the ion channel in the pathomechanism of OLP.

  5. TRPA1 DNA methylation (zeige HELLS Antikörper) in whole blood cells are associated with pain symptoms in chronic pain patients.

  6. Here we highlight the role of TRPA1 as a multipurpose sensor of harmful signals and as a sensor of stress and tissue damage.

  7. Three negatively charged amino acids near the outer pore vestibule are involved in heat-evoked TRPA1 activation in the presence of extracellular calcium.

  8. These results suggest that IL-1alpha enhances the translocation of TRPA1 to the plasma membrane via the activation of Erk (zeige EPHB2 Antikörper) in A549.

  9. Respiratory syncytial virus and measles virus infection upregulates TRPA1 expression in bronchial epithelial cells.

  10. Protein kinase A is an important kinase acting downstream of inflammatory mediators to cause sensitization of TRPA1.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Interaktionspartner

  1. Reducing agents reverse thiazolidine-induced TRPA1 activation, and mutagenesis studies show that nucleophilic cysteine residues in TRPA1 are critical, suggesting an activation mechanism involving thioreactive chemical reactions. In vivo studies show that thiazolidine induces acute pain and inflammation in mouse and these responses are specifically dependent on TRPA1.

  2. Data show that trigeminal transient receptor potential ankyrin 1 in the nasal cavity play an essential role in irritant-induced bradypnea.

  3. results provide evidence from two complementary and independent Advillin (zeige AVIL Antikörper)-Cre mouse lines indicating that TRPA1 specifically expressed within sensory neurons is essential for normal baseline sensitivity to multiple types of mechanical stimuli but not hot or cold temperature stimuli.

  4. This mechanistic pathway underlying TRPA1-mediated vasodilatation may be important in understanding the role of TRPA1 in pathophysiological situations.

  5. These findings demonstrate functional expression and the precise ultrastructural localization of TRPA1 and TRPV1 (zeige TRPV1 Antikörper) ion channels in freshly isolated mouse CMs (zeige Cd2ap Antikörper). Crosstalk between TRPA1 and TRPV1 (zeige TRPV1 Antikörper) may be important in mediating cellular signaling events in cardiac muscle

  6. TRPA1 and TRPV1 (zeige TRPV1 Antikörper) appear to contribute to the propofol-mediated antagonism of U46619-induced constriction in murine coronary microvessels that involves activation of NOS (zeige NOS Antikörper) and BKCa (zeige KCNMA1 Antikörper).

  7. The TRPA1 ion channel is expressed in CD4 (zeige CD4 Antikörper)+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1 (zeige TRPV1 Antikörper).

  8. TRPA1 channels trigger vesicle release in sensory neurons by releasing Calcium from lysosome-like organelles.

  9. Single exposure to acrolein causes cardiac dysfunction through TRPA1 activation.

  10. study revealed that TRPA1 positively modulates the mechanical hyperalgesia induced by B1 receptor activation in the spinal cord and that the classical GPCR downstream molecules

TRPA1 Antigen-Profil

Protein Überblick

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined\; however, studies indicate the function may involve a role in signal transduction and growth control.

Genbezeichner und Symbole assoziert mit TRPA1

  • transient receptor potential cation channel, subfamily A, member 1a (trpa1a) Antikörper
  • Transient receptor potential cation channel A1 (TrpA1) Antikörper
  • transient receptor potential cation channel subfamily A member 1 (TRPA1) Antikörper
  • transient receptor potential A1 (LOC658860) Antikörper
  • transient receptor potential cation channel subfamily A member 1 (LOC694623) Antikörper
  • tryptophan synthase subunit alpha 1 (trpA1) Antikörper
  • transient receptor potential cation channel, subfamily A, member 1 (trpa1) Antikörper
  • transient receptor potential cation channel subfamily A member 1 (Trpa1) Antikörper
  • TRPA cation channel homolog (trpa-1) Antikörper
  • transient receptor potential cation channel, subfamily A, member 1 (Trpa1) Antikörper
  • Anktm1 Antikörper
  • CG5751 Antikörper
  • CG5761 Antikörper
  • CT18073 Antikörper
  • dANKTM1 Antikörper
  • Dmel\\CG5751 Antikörper
  • DmTRPA1 Antikörper
  • dTrpA Antikörper
  • dtrpA1 Antikörper
  • FEPS Antikörper
  • GLEAN_02449 Antikörper
  • TrpA Antikörper
  • trpA1 Antikörper

Bezeichner auf Proteinebene für TRPA1

transient receptor potential cation channel subfamily A member 1 , CG5751-PG , CG5751-PH , CG5751-PI , CG5751-PJ , CG5751-PK , TrpA1-PG , TrpA1-PH , TrpA1-PI , TrpA1-PJ , TrpA1-PK , transient receptor potential A1 , transient receptor potential cation channel , transient-receptor-potential A1 , ankyrin-like protein 1 , transient receptor potential cation channel, subfamily A, member 1 , tryptophan synthase subunit alpha 1 , transient receptor potential cation channel subfamily A member 1-like , ankyrin-like with transmembrane domains 1 , ankyrin-like with transmembrane domains protein 1 , transformation-sensitive protein p120 , ANKTM1

GENE ID SPEZIES
474351 Danio rerio
39015 Drosophila melanogaster
420180 Gallus gallus
464230 Pan troglodytes
486994 Canis lupus familiaris
505317 Bos taurus
658860 Tribolium castaneum
694623 Macaca mulatta
9895859 Achromobacter xylosoxidans A8
100152934 Sus scrofa
100158526 Xenopus (Silurana) tropicalis
100414472 Callithrix jacchus
100460642 Pongo abelii
100526649 Cavia porcellus
178118 Caenorhabditis elegans
8989 Homo sapiens
277328 Mus musculus
312896 Rattus norvegicus
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