anti-Transformation/transcription Domain-Associated Protein (TRRAP) Antikörper

TRRAP encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. Zusätzlich bieten wir Ihnen Transformation/transcription Domain-Associated Protein Kits (2) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRRAP 8295 Q9Y4A5
TRRAP 100683  
TRRAP 288471  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Transformation/transcription Domain-Associated Protein Antikörper auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ChIP, IP   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details
Human Kaninchen Unkonjugiert IP, PLA, WB Western Blot and Immunoprecipitation: TRRAP Antibody [ABIN188802] - Detection of Human and Mouse TRRAP by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-TRRAP antibody ABIN188802 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. TRRAP was also immunoprecipitated by rabbit anti-TRRAP antibody ABIN188801, which recognizes an upstream epitope.  Detection: Chemiluminescence with exposure times of 30 seconds (A and B). Proximity Ligation Assay: TRRAP Antibody [ABIN1888021] - Secondary-Conjugate Duolink II PLA in Hela Cells. Goat anti-human DMAP1 (ABIN188802) and rabbit anti-human TRRAP (ABIN1888021). Image merged from DAPI (2ms) and Texas Red (100ms) exposures, 40X magnification. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: TRRAP Antibody [ABIN188801] - Detection of Human TRRAP by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-TRRAP antibody ABIN188801 used for IP at 3 mcg/mg lysate. TRRAP was also immunoprecipitated by rabbit anti- TRRAP antibody ABIN188802, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert WB   50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: TRRAP Antibody  - Staining of human cell line A-431 shows localization to nucleoplasm & the Golgi apparatus. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$295.90
Details
Huhn Kaninchen Unkonjugiert IP   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
Details
Huhn Kaninchen Unkonjugiert IP, PLA, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$925.83
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$925.83
Details

TRRAP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , , , ,
Mouse (Murine) , ,
, ,
,
Rat (Rattus) ,


Am meisten referenzierte anti-Transformation/transcription Domain-Associated Protein Antikörper

  1. Human Monoclonal TRRAP Primary Antibody für ChIP, IP - ABIN2668655 : Szutorisz, Canzonetta, Georgiou, Chow, Tora, Dillon: Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. in Molecular and cellular biology 2005 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Transformation/transcription Domain-Associated Protein Interaktionspartner

Human Transformation/transcription Domain-Associated Protein (TRRAP) Interaktionspartner

  1. Data suggest that ubiquitin thioesterase 7 (HAUSP (zeige USP7 Antikörper)) may act as an oncogenic protein that can modulate c-MYC (zeige MYC Antikörper) protein expression via transformation-transcription domain-associated protein (TRRAP).

  2. study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP (zeige CREBBP Antikörper), CBFA2T3 (zeige CBFA2T3 Antikörper), AMOTL1 (zeige AMOTL1 Antikörper), FAT4 (zeige FAT4 Antikörper), FBXO11 (zeige FBXO11 Antikörper), PLA2G4D, TRRAP and USH2A (zeige USH2A Antikörper).

  3. MYC associates with STAGA through extended interactions of the TAD with both TRRAP and GCN5.

  4. Findings establish Trrap as a critical part of the mechanism that restricts differentiation and promotes the maintenance of key features of ESCs (zeige NR2E3 Antikörper).

  5. TRRAP is targeted for destruction in a cell cycle-dependent fashion.

  6. The over-expression of TRA1 (zeige HSP90B1 Antikörper) in hepatocirrhosis and hepatocellular carcinoma is correlated with the formation and development of HCC (zeige FAM126A Antikörper).

  7. TRRAP harbors a recurrent mutation that clustered in one position (p. Ser722Phe) in 6 out of 167 melanoma samples (approx. 4%). The nature, pattern and functional evaluation of the TRRAP recurrent mutation suggest that TRRAP functions as an oncogene (zeige RAB1A Antikörper).

  8. knockdown of the adaptor protein TRRAP significantly increased differentiation of cultured brain tumor-initiating cells, sensitized the cells to apoptotic stimuli, and negatively affected cell cycle progression.

  9. TRRAP binding and the recruitment of histone H3 (zeige HIST3H3 Antikörper) and H4 acetyltransferase activities are required for the transactivation of a silent TERT (zeige TERT Antikörper) gene in exponentially growing human fibroblasts by c-Myc (zeige MYC Antikörper) or N-Myc protein (zeige MYCN Antikörper).

  10. Data suggest a model in which p53 (zeige TP53 Antikörper) directly recruits a TRRAP/acetyltransferase complex to the mdm2 (zeige MDM2 Antikörper) gene to activate transcription. In addition, this study defines a novel mechanism utilized by the p53 tumor suppressor (zeige TP53 Antikörper) to regulate gene expression.

Mouse (Murine) Transformation/transcription Domain-Associated Protein (TRRAP) Interaktionspartner

  1. TRRAP deficiency impairs B-cell development but does not directly affect class switch recombination (CSR (zeige SCARA3 Antikörper). Instead, cells induced to proliferate undergo apoptosis. Our findings demonstrate a central and general role of TRRAP in cell proliferation.

  2. expression profiles of Trrap-responsive genes, using cDNA microarray in mitotic cells

  3. Data show that the loss of Trrap leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap-mediated transcription of the mitotic checkpoint (zeige BUB3 Antikörper) proteins Mad1 (zeige MXD1 Antikörper) and Mad2 (zeige MXI1 Antikörper).

  4. HAT (zeige HAT Antikörper) cofactor Trrap and Tip60 (zeige KAT5 Antikörper) HAT (zeige HAT Antikörper) bind to the chromatin surrounding sites of DNA double-strand breaks (DSBs). Cells may use the same basic mechanism involving HAT (zeige HAT Antikörper) complexes to regulate distinct cellular processes, such as transcription and DNA repair.

  5. Fe65 (zeige APBB1 Antikörper) and its interaction with APP (zeige APP Antikörper) play an important role in the response to DNA damage by assisting the recruitment

  6. this study has identified a critical role for Trrap in the mechanism that maintains hematopoietic stem cells and hematopoietic system, and underscores the importance of Trrap and histone modifications in tissue homeostasis.

Transformation/transcription Domain-Associated Protein (TRRAP) Antigen-Profil

Protein Überblick

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit TRRAP

  • Phosphatidylinositol 3- and 4-kinase family protein with FAT domain-containing protein (AT2G17930) Antikörper
  • phosphotransferases/inositol or phosphatidylinositol kinase (AT4G36080) Antikörper
  • transcription-associated protein 1 (LOC5577036) Antikörper
  • transformation/transcription domain associated protein (TRRAP) Antikörper
  • transformation/transcription domain-associated protein (trrap) Antikörper
  • transformation/transcription domain associated protein (trrap) Antikörper
  • transformation/transcription domain-associated protein (TRRAP) Antikörper
  • transformation/transcription domain-associated protein (LOC100637779) Antikörper
  • transformation/transcription domain-associated protein (Trrap) Antikörper
  • AI481500 Antikörper
  • PAF350/400 Antikörper
  • PAF400 Antikörper
  • STAF40 Antikörper
  • T13L16.5 Antikörper
  • T13L16_5 Antikörper
  • TR-AP Antikörper
  • Tra1 Antikörper
  • trrap Antikörper

Bezeichner auf Proteinebene für TRRAP

transformation/transcription domain-associated protein , transformation/transcription domain-associated protein-like , 350/400 kDa PCAF-associated factor , tra1 homolog , transactivation/transformation-domain associated protein

GENE ID SPEZIES
816303 Arabidopsis thaliana
829764 Arabidopsis thaliana
5577036 Aedes aegypti
463564 Pan troglodytes
507169 Bos taurus
707047 Macaca mulatta
100158625 Xenopus (Silurana) tropicalis
100304461 Oryzias latipes
100374801 Saccoglossus kowalevskii
100411715 Callithrix jacchus
100455280 Pongo abelii
100637779 Amphimedon queenslandica
8295 Homo sapiens
100683 Mus musculus
288471 Rattus norvegicus
416440 Gallus gallus
479747 Canis lupus familiaris
100521781 Sus scrofa
Ausgewählte Anbieter für anti-Transformation/transcription Domain-Associated Protein (TRRAP) Antikörper
Haben Sie etwas anderes gesucht?