anti-Transcription Factor E3 (TFE3) Antikörper

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. Zusätzlich bieten wir Ihnen TFE3 Kits (8) und TFE3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TFE3 7030 P19532
TFE3 317376  
TFE3 209446 Q64092
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Top anti-TFE3 Antikörper auf antikoerper-online.de

Showing 10 out of 101 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-TFE3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-TFE3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from K562/A549 cells, using TFE3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TFE3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of TFE3 staining in PC12 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of TFE3 expression in HeLa (A), mouse lung (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert IP, WB Western blot analysis of TFE3. Lysate from WI-38 cells was probed with anti- TFE3 (clone G138-312) at concentrations of 1.0 (lane 1), 0.5 (lane 2), and 0.25 myg/ml (lane 3). TFE3 is identified as a band of 50 kDa. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$226.04
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$306.90
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details

TFE3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)
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Am meisten referenzierte anti-TFE3 Antikörper

  1. Human Polyclonal TFE3 Primary Antibody für ICC, IF - ABIN4361935 : Hong, Oh, Valera, Baba, Schmidt, Linehan: Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization. in PLoS ONE 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal TFE3 Primary Antibody für IP, WB - ABIN967449 : Beckmann, Su, Kadesch: TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. in Genes & development 1990 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen TFE3 Interaktionspartner

Human Transcription Factor E3 (TFE3) Interaktionspartner

  1. TFEB (zeige TFEB Antikörper) and TFE3 collaborate with each other in activated macrophages and microglia to promote efficient autophagy induction, increased lysosomal biogenesis, and transcriptional upregulation of numerous proinflammatory cytokines

  2. Findings indicated that TFE3 was an important hypoxia-induced transcriptional factor in HNSCC.

  3. Solid pseudopapillary neoplasms (SPNs) showed positive staining for SRY (zeige SRY Antikörper)-related high-mobility group box (zeige SSRP1 Antikörper) 11 (SOX-11 (zeige SOX11 Antikörper)), transcription factor E3 (TFE3) and beta-catenin (zeige CTNNB1 Antikörper) on cell blocks.

  4. results reveal that PRCC (zeige PRCC Antikörper)-TFE3 dual-fusion FISH probe is an efficient and concise technique for diagnosing PRCC (zeige PRCC Antikörper)-TFE3 RCC (zeige XRCC1 Antikörper) in paraffin-embedded tissue

  5. Case Report: Melanotic Xp11 renal cell carcinoma (zeige MOK Antikörper) with ARID1B (zeige ARID1B Antikörper)-TFE3 gene fusion.

  6. Studies identified TFEB (zeige TFEB Antikörper) and TFE3 as master modulators of stress response notably in the lysosomal biogenesis and autophagy with capability to upregulate hundreds of genes involved in intracellular clearance, catabolism, metabolic processes, and cellular homeostasis.

  7. Ovarian sclerosing stromal tumor strongly overexpress TFE3.

  8. Describe the unusual morphology and expanded the morphologic spectrum of SFPQ/PSF (zeige SFPQ Antikörper)-TFE3 renal cell carcinomas.

  9. Despite TFE3 over expression, TFE3 genetic alterations are less likely to be a major molecular event driving tumorigenesis in hepatic angiolipomas.

  10. we analyze 60 Xp11 translocation cancers by fluorescence in situ hybridization using custom bacterial artificial chromosome probes to establish their TFE3 fusion gene partner

Mouse (Murine) Transcription Factor E3 (TFE3) Interaktionspartner

  1. TFEB (zeige TFEB Antikörper) and TFE3 collaborate with each other in activated macrophages and microglia to promote efficient autophagy induction, increased lysosomal biogenesis, and transcriptional upregulation of numerous proinflammatory cytokines

  2. These data indicate that TFE3 and TFEB (zeige TFEB Antikörper) play a cooperative, rather than redundant, role in the control of the adaptive response of whole-body metabolism to environmental cues such as diet and physical exercise.

  3. Findings indicated that TFE3 was an important hypoxia-induced transcriptional factor in HNSCC.

  4. Tfe3 and Tfeb (zeige TFEB Antikörper) are required for the induced expression of Ppargamma2 (zeige PPARG Antikörper) and subsequently for adipogenic genes.

  5. Tfe3 overexpression in HSPCs impaired long-term hematopoietic reconstitution in vivo, recapitulating the Flcn (zeige FLCN Antikörper) KO phenotype, and supporting the notion that abnormal activation of Tfe3 contributes to the Flcn (zeige FLCN Antikörper) KO phenotype. Flcn (zeige FLCN Antikörper) KO mice develop an acute histiocytic hyperplasia in multiple organs, suggesting a novel function for Flcn (zeige FLCN Antikörper) in macrophage development

  6. TFEB (zeige TFEB Antikörper) and TFE3 are novel components of the integrated stress response

  7. Tfe3 is a critical transcription factor that regulates Pgc-1alpha (zeige PPARGC1A Antikörper) gene expression in myotubes

  8. A conditional expression in mice of the fusion gene ASPSCR1 (zeige ASPSCR1 Antikörper)-TFE3 from human alveolar soft part sarcoma (ASPS (zeige DARS Antikörper)) generated a model that recapitulates the human tumor histologically and by expression profile.

  9. Data from transgenic mice suggest Tfe3 controls lipid metabolism in adipose tissue (white, WAT; brown, BAT (zeige BAAT Antikörper)); TFE3 appears to be regulated by diet; up-regulation of TFE3 may inhibit expression of lipolysis genes in WAT and thermogenesis genes in BAT (zeige BAAT Antikörper).

  10. These findings indicated that TFE3 has a regulatory role in myoblast differentiation, and that transcriptional suppression of myogenin (zeige MYOG Antikörper) expression may be part of the mechanism of action.

TFE3 Antigen-Profil

Protein Überblick

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1)\; it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.

Genbezeichner und Symbole assoziert mit TFE3

  • transcription factor binding to IGHM enhancer 3 (TFE3) Antikörper
  • transcription factor binding to IGHM enhancer 3 (Tfe3) Antikörper
  • transcription factor binding to IGHM enhancer 3 S homeolog (tfe3.S) Antikörper
  • transcription factor E3 (Tfe3) Antikörper
  • bHLHe33 Antikörper
  • F830016E06Rik Antikörper
  • RCCP2 Antikörper
  • RCCX1 Antikörper
  • RGD1559642 Antikörper
  • Tcfe3 Antikörper
  • Tfe-3 Antikörper
  • TFEA Antikörper

Bezeichner auf Proteinebene für TFE3

class E basic helix-loop-helix protein 33 , transcription factor E family, member A , transcription factor E3 , transcription factor for IgH enhancer , transcription factor for immunoglobulin heavy-chain enhancer 3

GENE ID SPEZIES
7030 Homo sapiens
491872 Canis lupus familiaris
520800 Bos taurus
317376 Rattus norvegicus
495043 Xenopus laevis
209446 Mus musculus
Ausgewählte Anbieter für anti-TFE3 (TFE3) Antikörper
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