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anti-Transcription Factor 12 (TCF12) Antikörper

The protein encoded by TCF12 is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. Zusätzlich bieten wir Ihnen TCF12 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TCF12 6938 Q99081
TCF12 21406 Q61286
TCF12 25720 P51514
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Top anti-TCF12 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TCF12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-TCF12  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  TCF12 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB TCF12 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TCF12 antibody detected the TCF12 protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of TCF12 in HeLa cell lysate with TCF12 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-TCF12 Antibody Titration: 0.06ug/mlELISA Titer: 1:1562500Positive Control: Human Lung Host: Rabbit  Target Name: TCF12  Sample Tissue: Human Fetal Brain  Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-TCF12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to TCF12 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of TCF12 expression in transfected 293T cell line by TCF12 monoclonal antibody (M01), clone 2E9. Lane 1: TCF12 transfected lysate(75.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details

TCF12 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TCF12 Antikörper

  1. Cow (Bovine) Polyclonal TCF12 Primary Antibody für WB - ABIN2780487 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Zeige alle 2 Referenzen für ABIN2780487

  2. Chicken Polyclonal TCF12 Primary Antibody für WB - ABIN2774659 : Wissmüller, Kosian, Wolf, Finzsch, Wegner: The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. in Nucleic acids research 2006 (PubMed)
    Zeige alle 2 Referenzen für ABIN2774659

  3. Human Polyclonal TCF12 Primary Antibody für EIA, WB - ABIN783743 : Murre, McCaw, Vaessin, Caudy, Jan, Jan, Cabrera, Buskin, Hauschka, Lassar: Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. in Cell 1989 (PubMed)
    Zeige alle 2 Referenzen für ABIN783743

  4. Human Polyclonal TCF12 Primary Antibody für EIA, WB - ABIN955126 : Schotte, Dontje, Nagasawa, Yasuda, Bakker, Spits, Blom: Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

Weitere Antikörper gegen TCF12 Interaktionspartner

Human Transcription Factor 12 (TCF12) Interaktionspartner

  1. HEB may be involved in GBM cell proliferation, as HEB silencing reduced proliferation in cells cultured as monolayers or neurospheres. Furthermore, the results suggested a potential role for HEB in the maintenance of GBM stem cells, as HEB silencing affected the differentiation capacity of cells.

  2. Two novel translocations leading to the inactivation of RUNX1 (zeige RUNX1 Antikörper) and its partners SIN3A (zeige SIN3A Antikörper) and TCF12 in myeloid leukemia (zeige BCL11A Antikörper).

  3. Studies suggest that transcription factor 12 (TCF12) should be included in level 2 genetic testing.

  4. show that these mutations compromise TCF12 transcriptional activity and are associated with a more aggressive tumour type

  5. several familial cases of coronal synostosis associated with mutations in TCF12

  6. In t(8;21) leukemia cells, the two E proteins, HEB and E2A (zeige TCF3 Antikörper), function as components of the stable AML1 (zeige RUNX1 Antikörper)-ETO (zeige RUNX1T1 Antikörper)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  7. haploinsufficiency of TCF12 causes coronal synostosis in humans and that severe bilateral coronal synostosis occ (zeige TWIST1 Antikörper)urs in mice with 50% of the wild-type dosage of both the T (zeige TWIST1 Antikörper)cf12 and Twist1 genes highlights the key role of TCF12 acting with TWIST1.

  8. the CD91 (zeige LRP1 Antikörper)/IKK (zeige CHUK Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling cascade is involved in secreted HSP90alpha (zeige HSP90AA2 Antikörper)-induced TCF12 expression, leading to E-cadherin (zeige CDH1 Antikörper) down-regulation and enhanced CRC (zeige CALR Antikörper) cell migration/invasion

  9. TCF12 functioned as a transcriptional repressor of E-cadherin (zeige CDH1 Antikörper) and its overexpression was significantly correlated with the occurrence of CRC (zeige CALR Antikörper) metastasis.

  10. HEB and E2A (zeige TCF3 Antikörper)-bind the SCA motif at regions overlapping SMAD2 (zeige SMAD2 Antikörper)/3 and FOXH1 (zeige FOXH1 Antikörper)

Mouse (Murine) Transcription Factor 12 (TCF12) Interaktionspartner

  1. HEB (zeige FREM1 Antikörper) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  2. severe bilateral coronal synostosis occurs in mice with 50% of the wild-type dosage of both the Tcf12 and Twist1 (zeige TWIST1 Antikörper) genes highlights the key role of TCF12 acting with TWIST1 (zeige TWIST1 Antikörper) in the normal development of the coronal sutures

  3. Deficiency in the E proteins, E2A (zeige TCF3 Antikörper) and HEB (zeige FREM1 Antikörper), led to increased frequency of terminally differentiated effector KLRG1 (zeige KLRG1 Antikörper)(hi) CD8 (zeige CD8A Antikörper)(+) T cells in mice during infection, and decreased generation of longer-lived memory-precursor cells during the immune response.

  4. Deletion of HEB (zeige FREM1 Antikörper) and E2A (zeige TCF3 Antikörper) in DP thymocytes specifically blocked the development of CD4 (zeige CD4 Antikörper)(+) lineage T cells. Furthermore, deletion of the E protein inhibitors Id2 and Id3 (zeige ID3 Antikörper) allowed CD4 (zeige CD4 Antikörper)(+) T cell development but blocked CD8 (zeige CD8A Antikörper)(+) lineage development.

  5. the earliest event in B-cell specification involves the induction of FOXO1 (zeige FOXO1 Antikörper) expression and requires the combined activities of E2A (zeige TCF3 Antikörper) and HEB (zeige FREM1 Antikörper)

  6. These results showed a new set of interactions between HEB (zeige FREM1 Antikörper), Notch1 (zeige NOTCH1 Antikörper), and GATA3 (zeige GATA3 Antikörper) that regulate the T-cell fate choice in developing thymocytes.

  7. Developmental progression of fetal HEB (zeige FREM1 Antikörper)(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.

  8. HEB (zeige FREM1 Antikörper) is a specific and essential factor in T-cell development and in the generation of the iNKT cell lineage.

  9. the dosage of HEB (zeige FREM1 Antikörper) determines pT alpha (zeige PTCRA Antikörper) gene expression in immature T cells

  10. the Tcf12 gene may be involved in the control of proliferating neural stem cells and progenitor cells

TCF12 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Genbezeichner und Symbole assoziert mit TCF12

  • transcription factor 12 (TCF12) Antikörper
  • transcription factor 12 (LOC100339415) Antikörper
  • transcription factor 12 (tcf12) Antikörper
  • transcription factor 12 (Tcf12) Antikörper
  • transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) (tcf12) Antikörper
  • A130037E08Rik Antikörper
  • ALF1 Antikörper
  • bHLHb20 Antikörper
  • CRS3 Antikörper
  • HEB Antikörper
  • HEBAlt Antikörper
  • HsT17266 Antikörper
  • HTF-4 Antikörper
  • HTF4 Antikörper
  • ME1 Antikörper
  • REB Antikörper
  • SCBPA Antikörper
  • TCF12 Antikörper
  • wu:fb74g05 Antikörper
  • wu:fc43e06 Antikörper
  • zgc:85956 Antikörper
  • zgc:110341 Antikörper

Bezeichner auf Proteinebene für TCF12

transcription factor 12 , transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) , DNA-binding protein HTF4 , E-box-binding protein , TCF-12 , class B basic helix-loop-helix protein 20 , helix-loop-helix transcription factor 4 , transcription factor HTF-4 , class A helix-loop-helix transcription factor ME1 , SCBP alpha , SCBP-alpha , salivary-specific cAMP response element-binding protein alpha , TF12 , basic helix-loop-helix protein , class A helix-loop-helix transcription factor GE1 , XE1.1

GENE ID SPEZIES
453466 Pan troglodytes
100339415 Oryctolagus cuniculus
100460448 Pongo abelii
100553875 Anolis carolinensis
100603993 Nomascus leucogenys
6938 Homo sapiens
509039 Bos taurus
21406 Mus musculus
25720 Rattus norvegicus
407985 Danio rerio
396334 Gallus gallus
100684199 Canis lupus familiaris
399451 Xenopus laevis
Ausgewählte Anbieter für anti-TCF12 (TCF12) Antikörper
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