anti-Transcription Elongation Factor SPT5 (SUPT5H) Antikörper

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. Zusätzlich bieten wir Ihnen Transcription Elongation Factor SPT5 Proteine (7) und Transcription Elongation Factor SPT5 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SUPT5H 6829 O00267
SUPT5H 20924 O55201
SUPT5H 308472  
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Top anti-Transcription Elongation Factor SPT5 Antikörper auf antikoerper-online.de

Showing 10 out of 52 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human kidney Human Pancreas 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SUPT5H Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB SUPT5H Antibody (Center) (ABIN658454) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the SUPT5H antibody detected the SUPT5H protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: SUPT5H Antibody [ABIN2582273] - FFPE section of human breast adenocarcinoma. Affinity purified rabbit anti-SUPT5H used at a dilution of 1:250. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SUPT5H Antibody  - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm. Immunohistochemistry-Paraffin: SUPT5H Antibody  - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Huhn Kaninchen Unkonjugiert IHC (p), WB   50 μg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details

SUPT5H Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Transcription Elongation Factor SPT5 Antikörper

  1. Cow (Bovine) Polyclonal SUPT5H Primary Antibody für WB - ABIN2778245 : Ueki, Lin, Senoo, Ebihara, Agata, Onji, Saheki, Kawai, Mukherjee, Reichenberger, Olsen: Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. in Cell 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal SUPT5H Primary Antibody für IHC (p), IHC - ABIN258227 : Lu, Xue, Xue, Yu, Arias, Lin, Fong, Faure, Weisburd, Ji, Mercier, Sutton, Luo, Gao, Zhou: Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism. in eLife 2015 (PubMed)

  3. Human Polyclonal SUPT5H Primary Antibody für ICC, IF - ABIN4356987 : Arabi, Ullah, Branca, Johansson, Bandarra, Haneklaus, Fu, Ariës, Nilsson, Den Boer, Pokrovskaja, Grandér, Xiao, Rocha, Lehtiö, Sangfelt: Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway. in Nature communications 2012 (PubMed)

Weitere Antikörper gegen Transcription Elongation Factor SPT5 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Transcription Elongation Factor SPT5 (SUPT5H) Interaktionspartner

  1. Spt5 interacts both physically and genetically with the Polycomb (zeige CBX2 Antikörper) Group (PcG) protein Pleiohomeotic (Pho)

  2. We show that SPT5 interacts directly with MSL1 in vitro and is required downstream of MSL complex recruitment, providing the first mechanistic data corroborating the elongation model of dosage compensation.

  3. Spt5 acts both positively and negatively on transcription in vivo during heat shock induction.

Arabidopsis thaliana Transcription Elongation Factor SPT5 (SUPT5H) Interaktionspartner

  1. SPT5-like protein emerged in plants as a facultative RNA polymerase elongation factor (zeige TSFM Antikörper).[SPT5]

Mouse (Murine) Transcription Elongation Factor SPT5 (SUPT5H) Interaktionspartner

  1. Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells.

  2. our findings indicate that Spt4 (zeige SUPT4H1 Antikörper) and Spt5 have essential functions in the DNA repair phase of immunoglobulin class switch recombination.

  3. Study reports that Spt5, a factor normally associated with stalled or paused Pol II, is required for class switch recombination.

Zebrafish Transcription Elongation Factor SPT5 (SUPT5H) Interaktionspartner

  1. the positive function of Foggy/Spt5 is required for gata1 (zeige GATA1 Antikörper) expression during zebrafish embryonic hematopoiesis.

  2. RNA polymerase II elongation repression is critically dependent on the C-terminus of Spt5

  3. The elongation factors Pandora/Spt6 (zeige SUPT6H Antikörper) and Foggy/Spt5 promote transcription in the zebrafish embryo.

  4. spt 5-dependent transcript elongation is required cell-autonomously for a complex cell migration

  5. Spt5 as a dual regulator of transcription elongation in vivo; a small but diverse set of target genes critically dependent on Spt5 during development.

Human Transcription Elongation Factor SPT5 (SUPT5H) Interaktionspartner

  1. The mobile C-terminal region of DSIF is located near exiting RNA, where it can recruit factors for RNA processing.

  2. OGA (zeige MGEA5 Antikörper) is physically associated with the known RNA polymerase II (pol II) pausing/elongation factors SPT5 and TRIM28-KAP1-TIF1beta (zeige TRIM28 Antikörper), and a purified OGA (zeige MGEA5 Antikörper)-SPT5-TIF1beta (zeige TRIM28 Antikörper) complex has elongation properties.

  3. A transcription-independent effect of tumor necrosis factor alpha (zeige TNF Antikörper) on RNA splicing, mediated by Spt5.

  4. SPT5 contributes to the up-regulation of hTERT expression and colonic tumor development.

  5. Data indicate that the Plus3 domain of the Rtf1 (zeige RTF1 Antikörper) subunit mediates Paf1C recruitment to genes by binding a repeating domain within the phosphorylated elongation factor (zeige TSFM Antikörper) Spt5.

  6. DSIF Is Selectively Required for mRNA Splicing and Export of NF-kappaB (zeige NFKB1 Antikörper) Target Genes.

  7. RNA polymerase II elongation repression is critically dependent on the C-terminus of Spt5

  8. crystal structure of hSpt4 (zeige SUPT4H1 Antikörper) in complex with the dimerization region of hSpt5

  9. phosphorylated by P-TEFb (zeige CCNT1 Antikörper) kinase during HIV-1 transcription in Tat (zeige TAT Antikörper)/TAR (zeige RBM8A Antikörper) dependent manner

  10. hSpt5 function in transcription regulation and mRNA capping is essential for a subset of cellular and viral genes and may not be required for global gene expression.

Transcription Elongation Factor SPT5 (SUPT5H) Antigen-Profil

Protein Überblick

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.

Genbezeichner und Symbole assoziert mit SUPT5H

  • SPT5 homolog, DSIF elongation factor subunit (SUPT5H) Antikörper
  • suppressor of Ty 5 (Supt5) Antikörper
  • transcription elongation factor SPT5 (LOC413814) Antikörper
  • Transcription elongation factor Spt5 (AT2G34210) Antikörper
  • transcription elongation factor Spt5 (spt5) Antikörper
  • transcription elongation factor spt5 (MGYG_08422) Antikörper
  • transcription elongation factor spt5 (TERG_05483) Antikörper
  • hypothetical protein (PGTG_18458) Antikörper
  • SPT5 homolog, DSIF elongation factor subunit (supt5h) Antikörper
  • SPT5 homolog, DSIF elongation factor subunit (Supt5h) Antikörper
  • SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S) Antikörper
  • CG7626 gene product from transcript CG7626-RA (Spt5) Antikörper
  • Transcription elongation factor SPT5 (spt-5) Antikörper
  • transcription elongation factor (SPT5) Antikörper
  • AL033283 Antikörper
  • AL033321 Antikörper
  • AU019549 Antikörper
  • CaO19.1453 Antikörper
  • CG7626 Antikörper
  • dDSIF Antikörper
  • Dmel\\CG7626 Antikörper
  • DSIF Antikörper
  • dSpt5 Antikörper
  • etID10129.15 Antikörper
  • etID37101.15 Antikörper
  • F13P17.5 Antikörper
  • F13P17_5 Antikörper
  • fb37g01 Antikörper
  • fb95e05 Antikörper
  • fog Antikörper
  • foggy Antikörper
  • spt5 Antikörper
  • spt5h Antikörper
  • Supt5h Antikörper
  • tat-ct1 Antikörper
  • wu:fb37g01 Antikörper
  • wu:fb95e05 Antikörper
  • wu:fc10f02 Antikörper

Bezeichner auf Proteinebene für SUPT5H

DRB sensitivity-inducing factor 160 kDa subunit , DRB sensitivity-inducing factor large subunit , DSIF large subunit , DSIF p160 , Tat-cotransactivator 1 protein , hSPT5 , transcription elongation factor SPT5 , suppressor of Ty 5 homolog , transcription elongation factor Spt5 , transcription elongation factor spt5 , protein foggy , transcription elongation regulator foggy , CG7626-PA , Spt5-PA , Chromatin elongation factor SPT5

GENE ID SPEZIES
6829 Homo sapiens
20924 Mus musculus
413814 Apis mellifera
817982 Arabidopsis thaliana
2541916 Schizosaccharomyces pombe 972h-
10024747 Arthroderma gypseum CBS 118893
10372474 Trichophyton rubrum CBS 118892
10537737 Puccinia graminis f. sp. tritici CRL 75-36-700-3
64275 Danio rerio
308472 Rattus norvegicus
426493 Gallus gallus
476462 Canis lupus familiaris
733281 Xenopus laevis
519808 Bos taurus
53442 Drosophila melanogaster
178143 Caenorhabditis elegans
100713914 Cavia porcellus
3635847 Candida albicans SC5314
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