Tissue Factor Pathway Inhibitor 2 Proteine (TFPI2)

TFPI2 encodes a member of the Kunitz-type serine proteinase inhibitor family. Zusätzlich bieten wir Ihnen TFPI2 Antikörper (133) und TFPI2 Kits (40) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TFPI2 7980 P48307
TFPI2 21789 O35536
TFPI2 286926  
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Showing 10 out of 26 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
HEK-293 Cells Human His tag Human TFPI-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$341.00
Details
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$437.80
Details
HEK-293 Cells Human His tag 10 μg Anmelden zum Anzeigen 2 bis 3 Tage
$230.00
Details
HEK-293 Human Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$206.55
Details
Nicotiana benthamiana Human His tag Panel A show SDS-PAGE 15 % Coomassie Blue of AGV 212 trypsin inhibitor purified by Gel filtration. Lane 1: Precision Plus Protein Standards cat 161-0363 BIORAD, lane 2: AGV 212 1mg/mL. Panel B show lane 1: Kaleidoscope Prestained Standards cat 161-0324 BIORAD, lane 2: the same samples analyzed by Western Blot with specific antiserum. All bands observed shown the same peptide mass finger printing pattern, corresponding to AGV212. Post-translational modifications do exist among the different bands nevertheless they do not alter their activity The activity of the inhibitor is expressed as the amount of trypsin inhibited per milligram of inhibitor. The ability to prevent the hydrolysis of benzoyl-L-arginine ethyl ester hydrochloride by trypsin is measured by spectrophotometer. One mg protein will inhibit 1-1.5 mg trypsin with activity of approximately 10, 000 BAEE units per mg protein. 1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$346.50
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
Details
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details

TFPI2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , , , ,
,
Mouse (Murine) , ,
,
Rat (Rattus)

Weitere Proteine zu Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartnern

Zebrafish Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

Human Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

  1. estrogen induced TFPI-2 expression in MCF7 cells is mediated by ERalpha (zeige ESR1 Proteine) and also by the action of LSD1 (zeige KDM1A Proteine).

  2. TFPI2 hypermethylation is associated with colorectal cancer.

  3. our research indicated that miR (zeige MLXIP Proteine)-130a functions as an oncogene (zeige RAB1A Proteine) by targeting TFPI2, miR (zeige MLXIP Proteine)-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK (zeige PTK2 Proteine)/PI3K (zeige PIK3CA Proteine)/Rac1/mdm2 (zeige MDM2 Proteine) pathway

  4. TFPI-2 expression was decreased in bladder cancer. TFPI-2 expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.

  5. TFPI2 is a useful serum biomarker for preoperative clinical diagnosis of CCC.

  6. This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.

  7. Over-expression of TFPI-2 and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.

  8. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (zeige PRSS3 Proteine) accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.

  9. Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.

  10. DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.

Mouse (Murine) Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

  1. A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.

  2. Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.

  3. Bovine TFPI2 was compared to mouse TFPI2.

  4. human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species

  5. Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.

  6. Deficiency for the histone methyltransferase EHMT2 (zeige EHMT2 Proteine) or for the Polycomb group protein EED (zeige EED Proteine), leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.

  7. Dynamic changes of Tfpi2 associated with Il-1beta (zeige IL1B Proteine) and Tnf-alpha (zeige TNF Proteine) in the development of acute lung injury are reported.

Cow (Bovine) Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

  1. Bovine TFPI2 was cloned and its expression and characterization determined.

TFPI2 Protein Überblick

Protein Überblick

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit TFPI2

  • tissue factor pathway inhibitor 2 L homeolog (tfpi2.L)
  • tissue factor pathway inhibitor 2 (TFPI2)
  • tissue factor pathway inhibitor 2 (tfpi2)
  • tissue factor pathway inhibitor 2 (Tfpi2)
  • AV000670 Protein
  • MGC68843 Protein
  • MGC108301 Protein
  • PP5 Protein
  • PP5/TFPI-2 Protein
  • REF1 Protein
  • si:ch211-262k23.2 Protein
  • TFPI-2 Protein
  • tfpi2 Protein

Bezeichner auf Proteinebene für TFPI2

tissue factor pathway inhibitor 2 , tissue factor pathway inhibitor-2 , Tissue factor pathway inhibitor 2 , placental protein 5 , retinal pigment epithelium cell factor 1 , TFPI-2

GENE ID SPEZIES
379525 Xenopus laevis
463540 Pan troglodytes
548483 Xenopus (Silurana) tropicalis
560339 Danio rerio
700850 Macaca mulatta
100218198 Taeniopygia guttata
100305210 Oncorhynchus mykiss
100718882 Cavia porcellus
7980 Homo sapiens
21789 Mus musculus
286926 Rattus norvegicus
360007 Bos taurus
475230 Canis lupus familiaris
420561 Gallus gallus
101113838 Ovis aries
100520144 Sus scrofa
Ausgewählte Anbieter für TFPI2 Proteine (TFPI2)
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