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TFPI2 encodes a member of the Kunitz-type serine proteinase inhibitor family. Zusätzlich bieten wir Ihnen TFPI2 Antikörper (117) und TFPI2 Kits (37) und viele weitere Produktgruppen zu diesem Protein an.
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Human TFPI2 Protein expressed in HEK-293 - ABIN2666517
Lwaleed, Bass: Tissue factor pathway inhibitor: structure, biology and involvement in disease. in The Journal of pathology 2006
Zeige alle 8 Referenzen für ABIN2666517
Human TFPI2 Protein expressed in Human Cells - ABIN2003028
Miyagi, Koshikawa, Yasumitsu, Miyagi, Hirahara, Aoki, Misugi, Umeda, Miyazaki: cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2. in Journal of biochemistry 1995
Human TFPI2 Protein expressed in HEK-293 Cells - ABIN2181806
Rao, Liu, Peavey, Woodley: Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts. in Archives of biochemistry and biophysics 1995
TFPI-2 expression was decreased in bladder cancer. TFPI-2 expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.
TFPI2 is a useful serum biomarker for preoperative clinical diagnosis of CCC.
This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.
Over-expression of TFPI-2 and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.
Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (zeige PRSS3 Proteine) accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.
Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.
DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.
our findings suggested that the differential expression of MMP-2 (zeige MMP2 Proteine) and TFPI-2 have a negative correlation in pancreatic carcinoma
Our finding suggests that the decreased expression of TFPI-2 may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma
TMPRSS4 (zeige TMPRSS4 Proteine) is upregulated by silencing of TFPI-2 through aberrant DNA methylation (zeige HELLS Proteine) and contributes to oncogenesis in non-small cell lung cancer.
A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.
Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.
Bovine TFPI2 was compared to mouse TFPI2.
human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species
Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.
Deficiency for the histone methyltransferase EHMT2 (zeige EHMT2 Proteine) or for the Polycomb group protein EED (zeige EED Proteine), leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.
Dynamic changes of Tfpi2 associated with Il-1beta (zeige IL1B Proteine) and Tnf-alpha (zeige TNF Proteine) in the development of acute lung injury are reported.
Bovine TFPI2 was cloned and its expression and characterization determined.
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
tissue factor pathway inhibitor 2
, tissue factor pathway inhibitor-2
, Tissue factor pathway inhibitor 2
, placental protein 5
, retinal pigment epithelium cell factor 1