anti-Thimet Oligopeptidase 1 (THOP1) Antikörper

Involved in the metabolism of neuropeptides under 20 amino acid residues long. Zusätzlich bieten wir Ihnen Thimet Oligopeptidase 1 Kits (16) und Thimet Oligopeptidase 1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
THOP1 7064 P52888
THOP1 50492 Q8C1A5
THOP1 64517 P24155
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Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunohistochemistry: Thimet Oligopeptidase Antibody (4D6) [ABIN152914] - Analysis of Thimet Oligopeptidase in mouse brain using DAB with hematoxylin counterstain. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
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Human Kaninchen Unkonjugiert WB Host: Rabbit Target Name: THOP1 Sample Type: Hela Whole Cell lysates Antibody Dilution: 1.0ug/ml  THOP1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
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Human Maus Unkonjugiert IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY THOP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-THOP1. Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-THOP1 mouse monoclonal antibody. (ABIN2453723) 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
418,10 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: Thimet Oligopeptidase Antibody [NBP1-31547] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
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Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
626,83 €
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Human Kaninchen Unkonjugiert WB   0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Maus Kaninchen Unkonjugiert IP, ELISA, WB 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using THOP1 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
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Human Maus Biotin ICC, IF, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
381,00 €
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THOP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Thimet Oligopeptidase 1 Antikörper

  1. Monoclonal Thimet Oligopeptidase 1 Primary Antibody für IF, WB - ABIN534015 : Conn, Pietropaolo, Ju, Abraham: Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain. in Journal of neurochemistry 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Thimet Oligopeptidase 1 Primary Antibody für ICC, IF - ABIN152914 : Azizi, Kang, Freilinger, Gruber-Olipitz, Chen, Yang, Hengstschläger, Slavc, Lubec: Mitosis-dependent protein expression in neuroblastoma cell line N1E-115. in Journal of proteome research 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Thimet Oligopeptidase 1 Interaktionspartner

Human Thimet Oligopeptidase 1 (THOP1) Interaktionspartner

  1. THOP1 may have clinical potentials to be employed as a promising biomarker to identify individuals with better prognosis and a novel antitumor agent for therapy of patients with NSCLC

  2. Low THOP1 expression levels are associated with recurrence of hepatocellular carcinoma.

  3. TCEP. Data indicate that THIMET-oligopeptidase (TOP) oxidation by H2O2 and high valence states of hemeproteins does not lead to enzyme oligomerization.

  4. The semi-quantitative intracellular peptidome analyses of siRNA-transfected HEK293 cells shows that the levels of specific intracellular peptides are either increased or decreased upon EP24.15 inhibition.

  5. human thimet oligopeptidase crystal structure shows substrate recognition, regulation, and localization

  6. EP24.15 associates with AT1 (zeige AGTR1 Antikörper) and B2 receptors both at the plasma membrane and after receptor internalization

  7. Mutations at only two residues (Glu-469 and Arg-498) are required to swap specificity with neurolysin, a result that is confirmed by testing the two-mutant constructs.

  8. increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta (zeige APP Antikörper) load.

  9. Over 100 peptides were identified in human embryonic kidney 293 (HEK293) cells that are derived from intracellular proteins; many but not all of these peptides are substrates or products of EP24.15.

  10. interaction between EP24.15 and calmodulin (zeige CALM1 Antikörper) is regulated within cells and is important for the stimulated secretion of EP24.15 from HEK293 cells.

Mouse (Murine) Thimet Oligopeptidase 1 (THOP1) Interaktionspartner

  1. the cellular peptidases dipeptidyl peptidase 3 (DPP-3 (zeige DPP3 Antikörper)) and thimet oligopeptidase 1 (TOP-1 (zeige TOP1 Antikörper)), both of which are present in nonimmunogenic necrotic cells, eliminated proteasomal degradation products and blocked Ag cross-presentation

  2. Data show that Thimet oligopeptidase (TOP) is coexpressed with estrogen receptor alpha (zeige ESR1 Antikörper), and estradiol regulates TOP expression in a brain region-specific manner in female mice.

  3. EP24.15 association with lipid rafts on the extracellular surface precedes constitutive release of the peptidase into the extracellular milieu for its action on neuropeptides

  4. Melanoma cells secrete thimet oligopeptidase which have an important role in tumor proliferation/angiogenesis in vitro and in vivo.

  5. increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta (zeige APP Antikörper) load.

Cow (Bovine) Thimet Oligopeptidase 1 (THOP1) Interaktionspartner

  1. Cyclic strain putatively regulates both the mRNA expression and enzymatic function of EP24.15 and EP24.16 (zeige NLN Antikörper).

Thimet Oligopeptidase 1 (THOP1) Antigen-Profil

Protein Überblick

Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

Genbezeichner und Symbole assoziert mit THOP1

  • thimet oligopeptidase 1 (thop1) Antikörper
  • thimet oligopeptidase 1 (THOP1) Antikörper
  • thimet oligopeptidase (LOC397806) Antikörper
  • thimet oligopeptidase (Tc00.1047053506411.10) Antikörper
  • thimet oligopeptidase (Tc00.1047053511237.10) Antikörper
  • thimet oligopeptidase (Noca_4613) Antikörper
  • thimet oligopeptidase (ANI_1_1400064) Antikörper
  • thimet oligopeptidase (Mboo_2053) Antikörper
  • thimet oligopeptidase (AOR_1_880174) Antikörper
  • Thimet oligopeptidase (AnaeK_0425) Antikörper
  • Thimet oligopeptidase (Mpal_0768) Antikörper
  • Thimet oligopeptidase (Hoch_5061) Antikörper
  • Thimet oligopeptidase (mepd) Antikörper
  • thimet oligopeptidase 1 (Thop1) Antikörper
  • AI131655 Antikörper
  • AI327041 Antikörper
  • EP24.15 Antikörper
  • LOC397806 Antikörper
  • mepd Antikörper
  • MEPD_HUMAN Antikörper
  • MGC147297 Antikörper
  • MP78 Antikörper
  • thop1 Antikörper
  • TOP Antikörper
  • zgc:92589 Antikörper

Bezeichner auf Proteinebene für THOP1

thimet oligopeptidase 1 , thimet oligopeptidase-like , thimet oligopeptidase , Thimet oligopeptidase , endopeptidase 24.15 , PZ-peptidase , endo-oligopeptidase A , metalloendopeptidase , soluble metallo-endopeptidase , endopeptidase EC3.4.24.15

GENE ID SPEZIES
449659 Danio rerio
721578 Macaca mulatta
779863 Xenopus (Silurana) tropicalis
100020499 Monodelphis domestica
100385317 Callithrix jacchus
100455971 Pongo abelii
397806 Xenopus laevis
3535960 Trypanosoma cruzi strain CL Brener
3541015 Trypanosoma cruzi strain CL Brener
4596069 Nocardioides sp. JS614
4981318 Aspergillus niger CBS 513.88
5410686 Methanoregula boonei 6A8
5990506 Aspergillus oryzae RIB40
6785830 Anaeromyxobacter sp. K
7270509 Methanosphaerula palustris E1-9c
8547472 Haliangium ochraceum DSM 14365
100194867 Salmo salar
7064 Homo sapiens
50492 Mus musculus
64517 Rattus norvegicus
510889 Bos taurus
397442 Sus scrofa
476748 Canis lupus familiaris
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