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The protein encoded by TNS1 localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. Zusätzlich bieten wir Ihnen Tensin 1 Antikörper (35) und und viele weitere Produktgruppen zu diesem Protein an.
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TNS1 plays an essential role in TGF-beta (zeige TGFB1 ELISA Kits)-induced myofibroblast differentiation.
TNS1, MET, and TRKC (zeige NTRK3 ELISA Kits) tyrosine-phosphorylated proteins are upregulated during epithelial-mesenchymal transition induced with TGF-beta (zeige TGFB1 ELISA Kits), and predict the outcome in lung adenocarcinoma patients.
TNS1 polymorphism associated with COPD (zeige ARCN1 ELISA Kits) risk and lung function decline
data demonstrate that tensin1 is extensively phosphorylated on Ser (zeige SIGLEC1 ELISA Kits)/Thr (zeige TRH ELISA Kits) residues in cells and phosphorylation by p38 MAPK (zeige MAPK14 ELISA Kits) regulates the specificity of the tensin1 Src (zeige SRC ELISA Kits) homology 2 domain for binding to different proteins
The expression of tensin is increased in mesangial cells with stimulating of high concentrations of glucose.
Data show expression of TNS1, GSTCD, AGER (zeige AGER ELISA Kits), HTR4 (zeige HTR4 ELISA Kits) and THSD4 (zeige THSD4 ELISA Kits) in lung tissue and indicate potential targets for interventions to alleviate respiratory disease.
Results suggest that PP1alpha (zeige PPP1CA ELISA Kits) bound to tensin1 has effects in reducing migration and invasion that are not mediated through DLC-1 (zeige DYNLL1 ELISA Kits), and show the importance of PP1alpha (zeige PPP1CA ELISA Kits) binding to tensin1 for the regulation of cell polarization, migration, and invasion.
Tensin may play important roles in mesangial ECM (zeige MMRN1 ELISA Kits) production through an adhesion complex with integrin alpha5, FAK (zeige PTK2 ELISA Kits), and vinculin (zeige VCL ELISA Kits).
Results suggest that the protein-tyrosine phosphatase (zeige ACP1 ELISA Kits) domain of tensin exhibits isoform-specific association with PP1alpha (zeige PPP1CA ELISA Kits) in a restricted spatial region of adhesions that are formed during cell migration.
studies demonstrate that TNS1 binds to DLC1 (zeige DLC1 ELISA Kits) and fine-tunes its RhoGAP (zeige ARHGAP1 ELISA Kits) activity toward RhoA (zeige RHOA ELISA Kits) and that the TNS1-DLC1 (zeige DLC1 ELISA Kits)-RhoA (zeige RHOA ELISA Kits) signaling axis is critical in regulating cellular functions that lead to angiogenesis
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined.
, tensin 1
, Matrix-remodelling-associated protein 6
, matrix-remodelling associated 6