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Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Zusätzlich bieten wir Ihnen Tachykinin 4 Antikörper (19) und viele weitere Produktgruppen zu diesem Protein an.
Hemokinin-1, but not substance P (zeige TAC1 ELISA Kits) increases inflammation and hyperalgesia in the late phase of adjuvant-induced arthritis.
These findings suggest that tachykinins and NK1 (zeige HGF ELISA Kits) receptors play a key role in joint inflammation, rather than in nociceptive sensitization, in collagen antibody-induced arthritis A.
Our findings suggest a role for TAC4 in cell differentiation, and represent a regulatory bridge between the nervous system and the immune system.
cultures from TAC4(-/-) bone marrow, sorted "fraction B" pro-B cells or purified long-term reconstituting stem cells, contain higher numbers of pro-B cells compared with controls, suggesting an inhibitory role for HK-1 (zeige HK1 ELISA Kits) on developing B cells
Preprotachykinin (zeige TAC1 ELISA Kits) (PPT)-C genes are expressed in uterine cells, oocytes, ovaries and embryos from mice, and may play a role in female reproductive function.
HK-1 (zeige HK1 ELISA Kits) influences T-cell development, enhancing the proliferation of T-cell precursors and increased the number of thymocytes in fetal thymus organ cultures
Here we demonstrate the expression of mouse PPT-C (hemokinin 1 precursor) mRNA by CD11b (zeige ITGAM ELISA Kits)+ macrophages, CD11c (zeige ITGAX ELISA Kits)+ dendritic cells and in the microglial cell line EOC 13.31.
mouse hemokinin 1 and mouse hemokinin 1(2-11) are tachykinin NK(1) receptor-preferring uterotonic agonists in non-pregnant mice but lack action at the myometrial tachykinin NK(2) receptors present in late pregnant mice
Results suggest that Hemokinin-1 is regulated by a unique transcription regulation system that likely governs its differential expression pattern and suggests a role for Hemokinin-1 distinct from Substance P (zeige TAC1 ELISA Kits).
Kinase activation led to increased MMP-2 (zeige MMP2 ELISA Kits) and MT1-MMP (zeige MMP14 ELISA Kits) expression and melanoma cell migration induced by hHK-1 (zeige HOOK1 ELISA Kits). Thus, hHK-1 (zeige HOOK1 ELISA Kits) and the NK1 receptor (zeige TACR1 ELISA Kits) are critical to melanoma cell migration and each may be a promising chemotherapeutic target
Expression substance P/neurokinin A (zeige TAC1 ELISA Kits)/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 (zeige TAC1 ELISA Kits) receptors are dysregulated in uterine leiomyomata.
Data provide evidence for the first time that hemokinin-1, like substance P (zeige TAC1 ELISA Kits), may be involved in the pathophysiology of inflammatory bowel disease.
HK-1 (zeige KCNA4 ELISA Kits) and substance P (zeige TAC1 ELISA Kits) are novel T helper (Th)17 cell-inducing factors that may act locally on memory T cells to amplify inflammatory responses.
hHK-1 (zeige HOOK1 ELISA Kits) and its C-terminal fragments are human NK1 receptor (zeige TACR1 ELISA Kits) agonists with different functional selectivity properties and that such functional selectivity leads to differential activation of downstream signaling and receptor trafficking.
A possible association is found between a tachykinin-4 single nucleotide polymorphism and susceptibility to asthma.
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Hemokinin induces plasma extravasation, mast cell degranulation, muscle contraction, salivary secretion and scratching behavior. Increases sperm motility. Induces potent analgesic effects and may play a role in pain modulation. Promotes survival of bone marrow B lineage cells and of cultured LPS- stimulated pre-B cells and may act as an autocrine factor required for B-cell survival and proliferation. Lowers systemic arterial pressure following intravenous injection. Induces interferon-gamma production and may play a role in the inflammatory response. Shows potent affinity and specificity for the NK-1 receptor.
hemokinin I (HK-1)
, alpha tachykinin 4