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TAC3 encodes a member of the tachykinin family of secreted neuropeptides. Zusätzlich bieten wir Ihnen Tachykinin 3 Kits (41) und Tachykinin 3 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal Tachykinin 3 Primary Antibody für ICC, IHC (fro) - ABIN152542
Halasz, Zelena, Toth, Tulogdi, Mikics, Haller: Substance P neurotransmission and violent aggression: the role of tachykinin NK(1) receptors in the hypothalamic attack area. in European journal of pharmacology 2009
Show all 14 Pubmed References
Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin (zeige PDYN Antikörper) gene expression in the arcuate-median eminence.
steroidal environment and energy state negatively regulate kisspeptin (Kiss1 (zeige KISS1 Antikörper)), neurokinin B (Tac2), and dynorphin (Pdyn (zeige PDYN Antikörper)) gene expression.
This study showed a new evidence that furthers our understanding for the mechanisms underlying Tac2 (zeige TAC1 Antikörper)-dependent cellular pathways in fear learning.
Data show that estrogen receptor alpha (ERalpha (zeige ESR1 Antikörper)) in tachykinin 2 (zeige TAC1 Antikörper) protein (Tac2 (zeige TAC1 Antikörper)) neurons typically restrains pubertal onset and hypothalamic reproductive drive.
Tac2 (zeige TAC1 Antikörper)-/- females had delays in sexual maturation, with time to vaginal opening and first estrus occurring later than controls. However, cycling recovered in adulthood and Tac2 (zeige TAC1 Antikörper)-/- females were fertile, although they produced fewer pups per litter.
Increased Tac2 (zeige TAC1 Antikörper) expression, through a stress-induced PTSD-like model, or following lentiviral CeA (zeige CEA Antikörper) overexpression, are sufficient to enhance fear consolidation.
Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R (zeige TACR3 Antikörper) and KOR (zeige OPRK1 Antikörper)) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).
NKB could directly regulate secretion from NK3R-expressing GnRH neurons.
Tac2 (zeige TAC1 Antikörper) homozygous null mice responded normally to a series of algogenic (pain-inducing) and pruritic (itch-inducing) stimuli.
Preprotachykinin (zeige TAC1 Antikörper) (PPT)-B genes are expressed in uterine cells, oocytes, ovaries and embryos from mice, and may play a role in female reproductive function.
mutations in TAC (zeige IL2RA Antikörper) and TACR3 (zeige TACR3 Antikörper) are not a common cause for ICPP.
Colocalization experiments provided evidence for the presence of cocaine- and amphetamine-regulated transcript (zeige CARTPT Antikörper) (CART) in KP-immunoreactive (IR) and perikarya and in KP-IR and NKB-IR axon varicosities.
Amino acid substitution A63P in TAC3 gene was statistically associated with the puberty onset time in Chinese girls.
SP may influence the KP and NKB secretory output via additional autocrine/paracrine mechanisms or regulate GnRH neurosecretion directly.
Copper can enter cultured astrocytoma cells and subsequently open plasma membrane calcium channels, but when bound to NKB, copper ion uptake is inhibited.
Expression of the gene encoding NKB (TAC3) is up-regulated 20-fold in leiomyomas, compared with matched myometrium.
Rare variants in the TAC3 and TACR3 (zeige TACR3 Antikörper) genes were identified in patients with central pubertal disorders and loss-of-function variants of TACR3 (zeige TACR3 Antikörper) were associated with the normosmic IHH (zeige IHH Antikörper) phenotype.
these immunohistochemical data suggest an aging-related moderate enhancement in central NKB signaling.
NKB neurons in the arcuate nucleus do not synthesize detectable amounts of kisspeptin and dynorphin in young male humans. These data call for a critical use of the KNDy neuron terminology when referring to the pulse generator of the hypothalamus
NKB/NK(3)R and kisspeptin/KISS1R (zeige KISS1R Antikörper) are present in female peripheral reproductive tissues with colocalization of both systems in some non-neuronal cell populations of the human female genital tract.
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.
, neurokinin B
, preprotachykinin B
, tachykinin 3 (neuromedin K, neurokinin beta)
, neurokinin 2
, neurokinin A
, neurokinin B-like protein Zneurok1
, neurokinin alpha
, neuromedin L
, neuropeptide K
, substance K
, gamma tachykinin 3
, neuromedin K
, tachykinin 2
, neurokinin B, neuromedin K
, tachykinin 3, neurokinin beta