TRAF Interacting Protein Proteine (TRAIP)

TRAIP encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. Zusätzlich bieten wir Ihnen TRAIP Antikörper (52) und TRAIP Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TRAIP 10293 Q9BWF2
TRAIP 22036 Q8VIG6
Ratte TRAIP TRAIP 367167  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details

TRAIP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu TRAF Interacting Protein (TRAIP) Interaktionspartnern

Human TRAF Interacting Protein (TRAIP) Interaktionspartner

  1. TRIP interacts with transforming growth factor beta-activated kinase 1 (TAK1 (zeige MAP3K7 Proteine)) and promotes K48-linked polyubiquitination of TAK1 (zeige MAP3K7 Proteine) in rheumatoid arthritis fibroblast-Like synoviocytes

  2. Taken together, these findings improve the understanding clinical implication of TRAIP in various diseases including primordial dwarfism and cancers.

  3. cell cycle-dependent transcription of the TRAIP gene by E2F1 (zeige E2F1 Proteine), E2F2 (zeige E2F2 Proteine), and E2F4 (zeige E2F4 Proteine) and rapid protein degradation leads to cell cycle-dependent expression with a maximum in G2/M

  4. TRAIP/RNF206 is required for recruitment of RAP80 (zeige UIMC1 Proteine) to sites of DNA damage.(

  5. These findings establish TRAIP as a PCNA-binding ubiquitin ligase with an important role in protecting genome integrity after obstacles to DNA replication.

  6. TRAIP is a component of the DNA damage response to replication-blocking DNA lesions.TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.

  7. The TRAIP ubiquitin ligase activity is functionally required for the spindle assembly checkpoint control.

  8. a number of TRAIP mutants were used to define the TRAIP molecular domains responsible for its homo-dimerization. A co-immunoprecipitation assay indicated that the TRAIP forms homo-dimerization through the CC domain

  9. Data indicate that TRAF interacting protein (zeige TANK Proteine) TRIP negatively regulates the TNFR (zeige TNFRSF1A Proteine)-associated factor 2 (TRAF2 (zeige TRAF2 Proteine)) ubiquitin-dependent pathway by modulating the TRAF2 (zeige TRAF2 Proteine)-sphingosine 1-phosphate (S1P (zeige MBTPS1 Proteine)) interaction.

  10. The TRAF-interacting protein (zeige TANK Proteine) (TRIP) is a regulator of keratinocyte proliferation.

Mouse (Murine) TRAF Interacting Protein (TRAIP) Interaktionspartner

  1. TRIP as a negative regulator in TLR3 (zeige TLR3 Proteine)/4- and RIG-I (zeige DDX58 Proteine)-triggered antiviral responses and suggested TRIP as a potential target for the intervention of diseases with uncontrolled IFN-beta (zeige IFNB1 Proteine) production.

TRAIP Protein Überblick

Protein Überblick

This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.

Genbezeichner und Symbole assoziert mit TRAIP

  • TRAF interacting protein (TRAIP)
  • TRAF interacting protein L homeolog (traip.L)
  • TRAF-interacting protein (Traip)
  • MGC81341 Protein
  • RNF206 Protein
  • Trip Protein

Bezeichner auf Proteinebene für TRAIP

TRAF-interacting protein , TRAF interacting protein , ring finger protein 206

GENE ID SPEZIES
415927 Gallus gallus
431884 Xenopus laevis
10293 Homo sapiens
22036 Mus musculus
367167 Rattus norvegicus
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