TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) Proteine (TIPRL)

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA\; MIM 176915), PP4 (see PPP4C\; MIM 602035), and PP6 (see PPP6C\; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010].. Zusätzlich bieten wir Ihnen TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) Antikörper (51) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TIPRL 100362326  
TIPRL 261726 O75663
TIPRL 226591 Q8BH58
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HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.577,14 €
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.584,12 €
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TIPRL Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus)

Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) (TIPRL) Interaktionspartnern

Human TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) (TIPRL) Interaktionspartner

  1. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

  2. Unlike yeast TIP41, TIPRL has a positive effect on mTORC1 signaling through the association with PP2Ac (zeige PPP2CA Proteine).

  3. Data indicate that PP2A (zeige PPP2R4 Proteine) holoenzyme biogenesis and activity are controlled by five PP2A (zeige PPP2R4 Proteine) modulators, consisting of alpha4, PTPA (zeige PPP2R4 Proteine), LCMT1 (zeige LCMT1 Proteine), PME-1 (zeige PPME1 Proteine) and TIPRL1, which serve to prevent promiscuous phosphatase activity until the holoenzyme is completely assembled.

  4. TIPRL is highly up-regulated in human HCC (zeige FAM126A Proteine) samples and cell lines, compared with noncancerous liver tissues.

Mouse (Murine) TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) (TIPRL) Interaktionspartner

  1. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) (TIPRL) Protein Überblick

Protein Überblick

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA\; MIM 176915), PP4 (see PPP4C\; MIM 602035), and PP6 (see PPP6C\; MIM 612725) (McConnell et al., 2007

Genbezeichner und Symbole assoziert mit TIPRL

  • TIP41-like protein (PTMB.278)
  • TIP41-like protein (tiprl)
  • TIP41, TOR signalling pathway regulator-like (LOC100339654)
  • TIP41, TOR signalling pathway regulator-like (LOC100362326)
  • TIP41, TOR signalling pathway regulator-like (LOC100376749)
  • TIP41, TOR signaling pathway regulator-like (S. cerevisiae) (TIPRL)
  • TIP41, TOR signaling pathway regulator-like (S. cerevisiae) (Tiprl)
  • TIP41, TOR signalling pathway regulator-like (S. cerevisiae) (Tiprl)
  • 1810011K17Rik Protein
  • dJ69E11.3 Protein
  • RGD1310442 Protein
  • TIP Protein
  • TIP41 Protein
  • tiprl Protein

Bezeichner auf Proteinebene für TIPRL

TIP41-like protein , TIP41, TOR signalling pathway regulator-like , putative MAPK activating protein , putative MAPK-activating protein PM10 , type 2A-interacting protein

GENE ID SPEZIES
2898449 Paramecium tetraurelia strain d4-2
100196538 Salmo salar
100339654 Oryctolagus cuniculus
100362326 Rattus norvegicus
100376749 Saccoglossus kowalevskii
261726 Homo sapiens
480084 Canis lupus familiaris
540486 Bos taurus
360869 Rattus norvegicus
226591 Mus musculus
Ausgewählte Anbieter für TIP41, TOR Signaling Pathway Regulator-Like (S. Cerevisiae) Proteine (TIPRL)
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