anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) Antikörper

TIMP3 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP3 Kits (106) und TIMP3 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIMP3 7078 P35625
TIMP3 25358  
TIMP3 21859 P39876
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Showing 10 out of 190 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB TIMP3 Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TIMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody (ABIN668361), Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody , Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HuvEc cells, using TIMP3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB The TIMP-3 Antibody is used in Western blot to detect TIMP-3 in rat liver lysates. TIMP-3 staining in human stomach cancer. Paraffin-embedded human stomach cancer is stained with TIMP-3 Antibody used at 1:200 dilution. 0.1 mg Anmelden zum Anzeigen 6 bis 11 Tage
368,76 €
Details
Human Maus PE FACS Detection of TIMP-3 in MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human TIMP-3 PE-conjugated Monoclonal Antibody. Detection of TIMP-3 in MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human TIMP-3 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 3 bis 4 Tage
305,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TIMP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-TIMP3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-TIMP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-TIMP3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Anti-TIMP3 antibody, Western blotting Lane 1: Recombinant Human TIMP3 Protein 10ng Lane 2: Recombinant Human TIMP3 Protein 5ng Lane 3: Recombinant Human TIMP3 Protein 2.5ng 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert IHC (p) 7 mL Anmelden zum Anzeigen 25 bis 36 Tage
198,00 €
Details

TIMP3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TIMP3 Antikörper

  1. Human Polyclonal TIMP3 Primary Antibody für IF (p), IHC (p) - ABIN668361 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Zeige alle 5 Referenzen für 668361

  2. Human Polyclonal TIMP3 Primary Antibody für EIA, FACS - ABIN955222 : Wick, Härönen, Mumberg, Bürger, Olsen, Budarf, Apte, Müller: Structure of the human TIMP-3 gene and its cell cycle-regulated promoter. in The Biochemical journal 1995 (PubMed)
    Zeige alle 2 Referenzen für 955222

  3. Human Polyclonal TIMP3 Primary Antibody für IHC, ELISA - ABIN1585860 : Nakasone, Terasako-Saito, Yamazaki, Sato, Tanaka, Sakamoto, Kurita, Yamasaki, Wada, Ishihara, Kawamura, Machishima, Ashizawa, Kimura, Kikuchi, Tanihara, Kanda, Kako, Nishida, Yamada, Kanda: Impact of high-/middle-molecular-weight adiponectin on the synthesis and regulation of extracellular matrix in dermal fibroblasts. in Experimental hematology 2014 (PubMed)

  4. Human Monoclonal TIMP3 Primary Antibody für FACS - ABIN4896675 : Mahller, Vaikunth, Ripberger, Baird, Saeki, Cancelas, Crombleholme, Cripe: Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. in Cancer research 2008 (PubMed)

  5. Human Polyclonal TIMP3 Primary Antibody für ELISA, WB - ABIN1533421 : Silbiger, Jacobsen, Cupples, Koski: Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family. in Gene 1994 (PubMed)

Weitere Antikörper gegen TIMP3 Interaktionspartner

Human TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. Electrostatic potential calculations suggested a competition between negatively charged GAGs and highly negatively charged complement-like domains of LRP-1 (zeige LRP1 Antikörper) for the binding to a positively charged area of TIMP-3 as an underlying mechanism.

  2. TIMP3 overexpression after myocardial infarction improves myocardial structural remodeling and function by promoting angiogenesis and inhibiting early proteolysis.

  3. Single Nucleotide Variants of Candidate Genes in Aggrecan (zeige ACAN Antikörper) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  4. Our data suggest that miR (zeige MLXIP Antikörper)-206 may function as an inflammatory regulator and drive the expression of MMP9 (zeige MMP9 Antikörper) in M.tb-infected THP-1 (zeige GLI2 Antikörper) cells by targeting TIMP3, indicating that miR (zeige MLXIP Antikörper)-206 is a potential therapeutic target for patients with TB.

  5. Plasma TIMP3 is a biomarker for predicting the tumor stage in patients with oral squamous cell carcinoma .

  6. TIMP-3 K26A/K45A retained higher affinity for sulfated (zeige SULF1 Antikörper) glycosaminoglycans than K42A/K110A and exhibited increased affinity for ADAMTS-5 (zeige ADAMTS5 Antikörper) in the presence of heparin.

  7. Of the 225 genetic tests performed, 150 were for recessive IRD (zeige SCRIB Antikörper), and 75 were for dominant IRD (zeige SCRIB Antikörper). A positive molecular diagnosis was made in 70 (59%) of probands with recessive IRD (zeige SCRIB Antikörper) and 19 (26%) probands with dominant IRD (zeige SCRIB Antikörper). Thirty-two novel variants were identified; among these, 17 sequence changes in four genes were predicted to be possibly or probably damaging including: ABCA4 (zeige ABCA4 Antikörper) (14), BEST1 (zeige BEST1 Antikörper) (2), PRPH2 (zeige PRPH2 Antikörper) (1), and TIMP3

  8. Study evaluated MMP-12 (zeige MMP12 Antikörper) and TIMP-1 (zeige TIMP1 Antikörper), TIMP-2 (zeige TIMP2 Antikörper), TIMP-3, and TIMP-4 (zeige TIMP4 Antikörper) levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (zeige CSE1L Antikörper)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 (zeige MMP12 Antikörper) is related to critical CAS (zeige CSE1L Antikörper) independently on symptoms, moreover, TIMP-3 and TIMP-4 (zeige TIMP4 Antikörper) seem to be specifically related to stroke

  9. A total of 1096 subjects from eight studies were included in the present meta-analysis. Overall, a significant association between TIMP-3 methylation and gastric cancer risk was observed (OR = 8.65; 95% CI4.31-17.37; p < 0.001). Our results show a positive correlation between TIMP-3 promoter methylation and gastric cancer risk and that TIMP-3 promoter methylation may be used as a molecular marker for gastric cancer

  10. TIMP-3 expression is suppressed by promoter methylation in HCC (zeige FAM126A Antikörper).

Rabbit TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 (zeige MMP1 Antikörper) and decreased TIMP-3 secretion.

  2. TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased MMP-14 (zeige MMP14 Antikörper).

Cow (Bovine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. Reactive oxygen species mediate TGF-beta1 (zeige TGFB1 Antikörper)-induced TIMP-3 gene expression

  2. TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.

  3. TIMP3 mRNA expression level was upregulated by multidirectional articular motion.

Xenopus laevis TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. only the N-terminal, but not the C-terminal domain of TIMP-3, results in developmental defects.

  2. metamorphic tail and intestine RNA levels of TIMP-2 (zeige TIMP2 Antikörper), MT1-MMP (zeige MMP14 Antikörper) and Gel-A, but not MT3-MMP (zeige MMP24 Antikörper) or TIMP-3, are elevated during periods of cell death and proliferation

Mouse (Murine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. TIMP3 promotes normal microvascular endothelial cell barrier function, at least partially, through inhibition of metalloproteinase-dependent disruption of adherens junctions, and septic downregulation of TIMP3 may contribute to septic MVEC barrier dysfunction.

  2. data strongly suggest that TIMP3 has direct neuroprotective effects that can mitigate the deleterious effects associated with TBI, an area with few if any therapeutic options.

  3. Elevated levels of TIMP3 and vitronectin (zeige VTN Antikörper), acting downstream of Notch3 (zeige NOTCH3 Antikörper)(ECD (zeige ECD Antikörper)) deposition, play a role in CADASIL (zeige NOTCH3 Antikörper), producing divergent influences on early CBF (zeige CEBPZ Antikörper) deficits and later white matter lesions.

  4. 4-Hydroxyisoleucine improved insulin (zeige INS Antikörper) resistant-like state in 3T3-L1 adipocytes by targeting TACE (zeige ADAM17 Antikörper)/TIMP3 and the insulin (zeige INS Antikörper) signaling pathway.

  5. In a mouse model of prostate cancer, increased tumor growth, proliferation index, increased microvascular density, and invasion was observed in Pten (zeige PTEN Antikörper)(-/-), Timp3(-/-) prostate tumors compared to Pten (zeige PTEN Antikörper)(-/-), Timp3(+/+) tumors.

  6. Timp3 status determines p53 (zeige TP53 Antikörper), p38 (zeige CRK Antikörper) and Notch (zeige NOTCH1 Antikörper) coactivation to instruct hepatic cell fate and transformation.

  7. TIMP2 (zeige TIMP2 Antikörper) and TIMP3 play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function

  8. Expansion of stem cells counteracts age-related mammary regression in compound Timp1 (zeige TIMP1 Antikörper)/Timp3-deficient mice.

  9. lack of TIMP3 increases inflammation and polarizes macrophages towards a more inflammatory phenotype resulting in increased atherosclerosis.

  10. TIMP-3 KO mice exhibit enhanced metabolism, as reflected by a higher body temperature than WT mice, possibly due to increased mitochondrial activity.

Pig (Porcine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. These results suggest the crucial role of TIMP-3 in successful implantation and embryo survival and indicate the endometrial stromal decidualization-like in pigs.

TIMP3 Antigen-Profil

Protein Überblick

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Genbezeichner und Symbole assoziert mit TIMP3

  • metalloproteinase inhibitor 3 (CpipJ_CPIJ003282) Antikörper
  • TIMP metallopeptidase inhibitor 3 (TIMP3) Antikörper
  • Metalloproteinase inhibitor 3 (timp3) Antikörper
  • TIMP metallopeptidase inhibitor 3 (Timp3) Antikörper
  • TIMP metallopeptidase inhibitor 3 (timp3) Antikörper
  • tissue inhibitor of metalloproteinase 3 (Timp3) Antikörper
  • tissue inhibitor of metalloproteinase-3 (TIMP-3) Antikörper
  • HSMRK222 Antikörper
  • IMP-3 Antikörper
  • K222 Antikörper
  • K222TA2 Antikörper
  • SFD Antikörper
  • Timp-3 Antikörper
  • timp3 Antikörper
  • timp3-A Antikörper

Bezeichner auf Proteinebene für TIMP3

metalloproteinase inhibitor 3 , TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor metalloproteinase-3 , TIMP metallopeptidase inhibitor 3 , Metalloproteinase inhibitor 3 , MIG-5 protein , TIMP-3 , protein MIG-5 , tissue inhibitor of metalloproteinases 3 , tissue inhibitor of metalloproteinase-3 , tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor of metalloproteinase 3 , 21 kDa protein of extracellular matrix , tissue inhibitor of metalloproteinases-3

GENE ID SPEZIES
6034728 Culex quinquefasciatus
481289 Canis lupus familiaris
100135460 Papio anubis
100196821 Salmo salar
7078 Homo sapiens
100008690 Oryctolagus cuniculus
25358 Rattus norvegicus
282094 Bos taurus
100033947 Equus caballus
396483 Gallus gallus
373596 Xenopus laevis
574381 Macaca mulatta
100217407 Ovis aries
21859 Mus musculus
396775 Sus scrofa
Ausgewählte Anbieter für anti-TIMP3 (TIMP3) Antikörper
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