anti-TIMELESS Interacting Protein (TIPIN) Antikörper

Required for normal progression of S-phase. Zusätzlich bieten wir Ihnen TIPIN Proteine (10) und TIPIN Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIPIN 100359731  
TIPIN 54962 Q9BVW5
TIPIN 66131 Q91WA1
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Top anti-TIPIN Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TIPIN Antibody Titration: 0.2-1 ug/mlPositive Control: Human heart 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TIPIN Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert WB TIPIN Antibody (N-term) (ABIN1881887) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the TIPIN antibody detected the TIPIN protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
462,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
374,52 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p)   0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of TIPIN expression in transfected 293T cell line by TIPIN monoclonal antibody (M01), clone 1G11. Lane 1: TIPIN transfected lysate(34.496 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details

TIPIN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)



Human , ,
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Mouse (Murine)


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Am meisten referenzierte anti-TIPIN Antikörper

  1. Human Polyclonal TIPIN Primary Antibody für WB - ABIN1881887 : Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 1881887

  2. Human Polyclonal TIPIN Primary Antibody für ICC, IF - ABIN4359856 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Zeige alle 2 Referenzen für 4359856

  3. Human Polyclonal TIPIN Primary Antibody für EIA, WB - ABIN493490 : Chou, Elledge: Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Zeige alle 2 Referenzen für 493490

  4. Cow (Bovine) Polyclonal TIPIN Primary Antibody für WB - ABIN2784256 : Unsal-Kaçmaz, Chastain, Qu, Minoo, Cordeiro-Stone, Sancar, Kaufmann: The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. in Molecular and cellular biology 2007 (PubMed)

Weitere Antikörper gegen TIPIN Interaktionspartner

Xenopus laevis TIMELESS Interacting Protein (TIPIN) Interaktionspartner

  1. Mta2 (zeige MTA2 Antikörper) and Tipin cooperate to maintain replication fork integrity, especially on regions that are intrinsically difficult to duplicate.

  2. data indicate that Tipin/Tim1 (zeige TIMELESS Antikörper)/And1 (zeige WDHD1 Antikörper) form a complex that links stabilization of replication fork and establishment of sister chromatid cohesion

Human TIMELESS Interacting Protein (TIPIN) Interaktionspartner

  1. the 1.85 A crystal structure of a large N-terminal segment of human Timeless (zeige TIMELESS Antikörper), spanning amino acids 1-463, is presented and this region of human Timeless (zeige TIMELESS Antikörper) harbours a partial binding site for Tipin.

  2. TIPIN is important for the maintenance of DNA replication and represents a potential treatment target for the worst prognosis associated breast cancers, such as Triple-negative breast cancer.

  3. Tim-Tipin complex (or Tim alone) is able to associate with DNA polymerase epsilon bound to a 40-/80-mer (zeige MERTK Antikörper) DNA ligand.

  4. Tim-Tipin complex might play a role in coupling DNA unwinding and DNA synthesis by directly affecting the catalytic activities of replication fork proteins.

  5. We now show that cellular DNA replication fork pausing and protection factors Timeless (zeige TIMELESS Antikörper) (Tim) and Tipin (Timeless-interacting protein) accumulate at OriP during S phase of the cell cycle.

  6. RPA (zeige RPA1 Antikörper)-covered ssDNA not only supports recruitment and activation of ATR (zeige ANTXR1 Antikörper) but also, through Tipin and Claspin (zeige CLSPN Antikörper), it plays an important role in the action of ATR (zeige ANTXR1 Antikörper) on its critical downstream target Chk1 (zeige CHEK1 Antikörper)

  7. The results suggest that Timeless (zeige TIMELESS Antikörper)-Tipin functions as a replication fork stabilizer that couples DNA replication with sister chromatid cohesion established at replication forks.

  8. Tipin is a checkpoint mediator that cooperates with Tim and may regulate the nuclear relocation of Claspin (zeige CLSPN Antikörper) in response to replication checkpoint

  9. observation explains the similar checkpoint phenotypes observed in both Tipin- and Timeless (zeige TIMELESS Antikörper)-depleted cells

  10. TIM and Tipin are functional orthologs of their replisome-associated yeast counterparts capable of coordinating replication with genotoxic stress responses, and distinguishes mammalian TIM from the circadian-specific paralogs.

Mouse (Murine) TIMELESS Interacting Protein (TIPIN) Interaktionspartner

  1. mTIM (zeige TIMELESS Antikörper) promotes the nuclear localization of TIPIN, and TIPIN is capable of regulating mTIM (zeige TIMELESS Antikörper) activity by disrupting the ability of mTIM (zeige TIMELESS Antikörper) to form homo-multimeric complexes

  2. TIM and Tipin are functional orthologs of their replisome-associated yeast counterparts capable of coordinating replication with genotoxic stress responses, and distinguishes mammalian TIM from the circadian-specific paralogs.

  3. The tim-Tipin dysfunction creates an indispensible reliance on the ATR (zeige ATR Antikörper)-Chk1 (zeige CHEK1 Antikörper) pathway for continued DNA synthesis.

TIPIN Antigen-Profil

Protein Überblick

Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be required in the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity).

Genbezeichner und Symbole assoziert mit TIPIN

  • timeless interacting protein (tipin) Antikörper
  • TIMELESS interacting protein (TIPIN) Antikörper
  • timeless interacting protein (LOC100359731) Antikörper
  • timeless interacting protein (Tipin) Antikörper
  • XTimeless interacting protein (xtipin) Antikörper
  • 1110005A05Rik Antikörper
  • 1110018P21Rik Antikörper
  • MGC82649 Antikörper
  • RGD1564084 Antikörper
  • tipin Antikörper
  • zgc:91928 Antikörper

Bezeichner auf Proteinebene für TIPIN

timeless interacting protein , TIMELESS interacting protein , timeless-interacting protein , TIMELESS-interacting protein , CSM3 homolog , mitotic phosphoprotein 67

GENE ID SPEZIES
444047 Xenopus laevis
453525 Pan troglodytes
100126681 Xenopus (Silurana) tropicalis
100359731 Rattus norvegicus
445058 Danio rerio
415548 Gallus gallus
54962 Homo sapiens
100683743 Canis lupus familiaris
506176 Bos taurus
66131 Mus musculus
363076 Rattus norvegicus
394376 Xenopus laevis
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