TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Proteine (TIAL1)

The protein encoded by TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. Zusätzlich bieten wir Ihnen TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Antikörper (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TIAL1 7073 Q01085
TIAL1 21843 P70318
Ratte TIAL1 TIAL1 361655  
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Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,90 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
403,06 €
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TIAL1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaktionspartnern

Human TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaktionspartner

  1. Data suggest that TPD52 (tumor protein D52) and a TPD52 fragment (residues 78-280) along with TIA-1 (zeige TIA1 Proteine) (T-cell intracellular antigen-1) and TIAR (TIA-1-related protein) contribute to mRNA stability as cis (zeige CISH Proteine)-acting and trans-acting factors; 3prime-untranslated regions of TPD52, TPD53, and TPD54 regulate expression of their respective genes in a post-transcriptional manner by altering mRNA stability.

  2. results suggest that TIA-1 and TIAR are two new host factors that interact with 5-UTR of EV71 genome and positively regulate viral replication

  3. TIAL1 inhibition of the exon 8 exclusion led to a decrease in SIRT1 (zeige SIRT1 Proteine)-Exon8 mRNA levels.

  4. TIA proteins can function as long-term regulators of the ACTB (zeige ACTB Proteine) mRNA metabolism in mouse and human cells.

  5. A role for TIAR is identified in T-cells for control of translational specificity.

  6. findings demonstrate that TIAR recognition motif 2 (RRM2 (zeige RRM2 Proteine)), together with its C-terminal extension, is the major contributor for the high-affinity (nM) interactions of TIAR with target RNA sequences

  7. TIA1 (zeige TIA1 Proteine) and TIAR proteins are intron-associated positive regulators of SMN2 (zeige SMN1 Proteine) exon 7 splicing.

  8. Severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1alpha (zeige HIF1A Proteine) expression.

  9. Data show that TIA1 (zeige TIA1 Proteine) and TIAL1 bind at the same positions on human RNAs, and are consistent with a model where TIA proteins shorten the time available for definition of an alternative exon by enhancing recognition of the preceding 5' splice site.

  10. Data show that apoptotic (TIAR and TIA-1 (zeige TIA1 Proteine)) marker expression in thyroid tissues from adolescents with immune thyroid diseases is higher than in non-immune thyroid diseases.

Mouse (Murine) TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaktionspartner

  1. Silencing of TIAR in chronic myeloid leukemia cells strongly elevated BRCA1.

  2. TIA proteins can function as long-term regulators of the ACTB (zeige ACTB Proteine) mRNA metabolism in mouse and human cells.

  3. Either TIA1 (zeige TIA1 Proteine) or TIAR inactivation broadly alter normal development-associated signalling pathways in murine embryonic fibroblasts.

  4. study reports the importance of the tightly balanced expression of the RNA-binding protein TIAR for normal embryonic development, thereby emphasizing the role of post-transcriptional regulations in early embryonic programming

  5. prion (zeige PRNP Proteine)-like aggregation of TIA-1 (zeige TIA1 Proteine) regulates stress granules formation downstream of eIF2alpha (zeige EIF2A Proteine) phosphorylation in response to stress

  6. in addition to transcriptional regulation, another mechanism by which apigenin prevents COX-2 expression is through mediating TIAR suppression of translatino

  7. TIAR regulates the relative expression of TIA-1 (zeige TIA1 Proteine) isoforms.

  8. TIA1 (zeige TIA1 Proteine) and TIAL1 regulate the alternate splicing of lysyl hydroxylase 2 (zeige PLOD2 Proteine)

  9. The intronic splicing enhancer of minute virus of mice binds the cellular RNA-processing proteins TIA-1 (zeige TIA1 Proteine) and TIAR, which enhance usage of the nonconsensus donor.

  10. SOD1 (zeige SOD1 Proteine) sequesters Hu antigen R (HuR (zeige ELAVL1 Proteine)) and TIA-1-related protein (TIAR) and has a role in impaired post-transcriptional regulation of vascular endothelial growth factor

TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.

Genbezeichner und Symbole assoziert mit TIAL1

  • TIA1 cytotoxic granule-associated RNA binding protein (TIA1)
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1 (tial1)
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1)
  • Tia1 cytotoxic granule-associated RNA binding protein-like 1 (Tial1)
  • 5330433G13Rik Protein
  • AL033329 Protein
  • mTIAR Protein
  • TCBP Protein
  • TIAL1 Protein
  • tiar Protein
  • zgc:66130 Protein

Bezeichner auf Proteinebene für TIAL1

TIA1 cytotoxic granule-associated RNA binding protein-like 1 , nucleolysin TIAR , T-cluster binding protein , TIA-1-related nucleolysin , aging-associated gene 7 protein , TIA-1-related protein , Tial1 cytotoxic granule-associated RNA binding protein-like 1 , Tial1 cytotoxic granule-associated RNA-binding protein-like 1 , RNA binding protein TIAR (TIA-1 related) , Tial 1 cytotoxic granule-associated RNA- binding protein-like 1

GENE ID SPEZIES
771327 Gallus gallus
394107 Danio rerio
100381100 Xenopus laevis
7073 Homo sapiens
477841 Canis lupus familiaris
21843 Mus musculus
361655 Rattus norvegicus
614540 Bos taurus
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